



Midocent Tablet
Midodrine (2.5mg)
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Midocent Tablet is used to treat low blood pressure (hypotension). It is used in patients who experience dizziness due to low blood pressure while standing up suddenly from a sitting or lying position. This medicine causes tightening of blood vessels and results in an elevation of your blood pressure.
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Oct 2025 | 04:13 PM (IST)
Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 27 Oct 2025 | 04:13 PM (IST)
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General Information
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Product introduction
Midocent Tablet can be taken with or without food. This medicine is taken during daytime hours when people stand most often. However, it should not be taken if you are going to lie down for a long time after a dose. Headache, blurred vision, nausea, heartburn and difficulty in urination may be seen as side effects in some patients.
Uses of Midocent Tablet
- Treatment of Low blood pressure
Benefits of Midocent Tablet
Treatment of Low blood pressure
Midocent Tablet is used in adults to relieve low blood pressure, which may occur due to a sudden change in posture from lying to sitting or standing up (orthostatic hypotension), during an operation, or after an injury. This medicine helps bring the blood pressure within the normal range. It therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.
Midocent Tablet is used in adults to relieve low blood pressure, which may occur due to a sudden change in posture from lying to sitting or standing up (orthostatic hypotension), during an operation, or after an injury. This medicine helps bring the blood pressure within the normal range. It therefore prevents any sudden fall or even serious complications that might have otherwise followed due to low blood pressure.
Side effects of Midocent Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Midocent
- Flushing (sense of warmth in the face, ears, neck and trunk)
- Headache
- Nausea
- Rash
- Difficulty in urination
- Supine hypertension
- Urinary retention
- Goosebumps
How to use Midocent Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Midocent Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Midocent Tablet works
Midocent Tablet is an alpha-adrenergic agonist. It works by activating specific receptors on blood vessels. This causes the blood vessels to tighten, which increases blood pressure.
All substitutes for Midocent Tablet
For information purposes only. Consult a doctor before taking any medicine.
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Quick tips
- Take Midocent Tablet at least 4 hours before bedtime to avoid the risk of high blood pressure at night time.Â
- Monitor your blood pressure regularly while taking this medicine.Â
- Inform your doctor if you have a history of prostate disorder or blood circulation problems.
- Inform your doctor immediately if you notice symptoms of chest pain, palpitations, headache, shortness of breath, and blurred vision.
- Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Midocent Tablet. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
Midocent Tablet may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.

Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Midocent Tablet during breastfeeding is not available. Please consult your doctor.

Driving
CONSULT YOUR DOCTOR
It is not known whether Midocent Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.

Kidney
CONSULT YOUR DOCTOR
There is limited information available on the use of Midocent Tablet in patients with kidney disease. Please consult your doctor.

Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Midocent Tablet in patients with liver disease. Please consult your doctor.
Interaction with drugs
Taking Midocent with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate
Risperidone (Oral Route)
Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Midodrine may raise blood levels of the active form of Risperidone.
Moderate
Selegiline (Oral Route)
Do not consume Selegiline with Midodrine. If concurrent use is essential, your doctor may monitor your blood pressure frequently.
Moderate
Rasagiline (Oral Route)
If concurrent use is essential, your doctor may monitor your blood pressure frequently.
Moderate
Risperidone (Injection Route)
Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Midodrine may raise blood levels of the active form of Risperidone.
Moderate
Safinamide (Oral Route)
If concurrent use is essential, your doctor may monitor your blood pressure frequently.
Frequently asked questions
Yes, Midocent Tablet may cause high blood pressure when you are lying flat on your back (supine hypertension). This medicine should only be used by people whose low blood pressure affects their day-to-day lives and in people who cannot be treated successfully with other therapies.
Midocent Tablet may slow down the heart rate slightly. It should be used cautiously when used with other medicines (beta blockers, digitalis, etc.), which can further slow down the heart rate. Patients should be monitored if they experience symptoms that are suggestive of a slow heart rate.
You should not lie down immediately after taking Midocent Tablet because of the risk of supine hypertension (high blood pressure, which occurs when you are lying flat on your back). Therefore, it is recommended to take the last daily dose at least 4 hours before bedtime. To lower the chance of high blood pressure while lying down at night, try keeping your head raised.
Midocent Tablet takes about 1 hour to show its effects. However, the action lasts for a short time only, the effect persists for about 2-3 hours.
Midocent Tablet should be taken exactly as directed by your doctor. Midocent Tablet is taken orally with or without food. Swallow Midocent Tablet as a whole with a glass of water. Usually, it is advised to take the medicine three times a day [morning, midday, and late afternoon (before 6 pm)] with a gap of at least 3 hours. Take the last daily dose of Midocent Tablet before an evening meal and at least 4 hours before bedtime.
Midocent Tablet is not advised for patients having an allergy to any component of the product, severe heart disease, unusually slow heart rate, high blood pressure, or conditions causing tightening of the arteries. Along with that, treatment with Midocent Tablet should be avoided if the patient has an enlarged prostate gland, urinary retention (when the bladder can’t empty properly), pheochromocytoma (tumor of the adrenal medulla), acute or severe kidney disease, overactive thyroid, poor vision as a result of diabetes, and narrow-angle glaucoma (elevated pressure in the eye).
You may need to check your blood pressure and get your kidney and liver function tests done before you start taking Midocent Tablet. Once you begin the treatment, keep a constant track of your blood pressure and heart rate, especially after lying down.
Symptoms of supine hypertension include chest pain, palpitations, shortness of breath, headache, and blurred vision. If you develop these symptoms, tell your doctor immediately. The doctor may reduce the dose of Midocent Tablet or may discontinue treatment if the symptoms persist.
Using Midocent Tablet and metoprolol together can make your heart rate considerably slow. Hence, you need to be careful while using both together. If you experience slow pulse, dizziness, and fainting, inform your doctor as the dose of these medicines may need to be modified.
Fact Box
Chemical Class
Ethanolamine derivative
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Alpha-1 adrenoreceptor agonists
References
- Westfall TC, WestfallIn DP. Adrenergic Agonists and Antagonists. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 295.
- Biaggioni I, Robertson D. Adrenoreceptor Agonists & Sympathomimetic Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 139.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 915-16.
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
- Midodrine hydrochloride [Product Information]. Lower Parel, Mumbai: CiplaMed; 2023. [Accessed 05 Mar. 2025] (online) Available from:
- Midodrine Hydrochloride [Product Information]. Dublin, OH: Cardinal Health; 2024. [Accessed 05 Mar. 2025] (online) Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Healthix Lifesciences
Address: Shop No 1, Vijay Park , Gurugram
Address: Shop No 1, Vijay Park , Gurugram
Vendor Details
Country of origin: India
A licensed vendor partner from your nearest location will deliver Midocent Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
A licensed vendor partner from your nearest location will deliver Midocent Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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