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MEtrogyl Injection

Metronidazole (500mg)
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MEtrogyl Injection is an antibiotic medicine that helps your body fight infections caused by bacteria and parasites. It is used to treat infections of the liver, stomach, intestines, vagina, brain, heart, lungs, bones and skin.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS,
Last updated on 07 Aug 2026 | 01:05 AM (IST)
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100 ml Injection
Get by Monday, 10 August
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Gurgaon
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May, 2027

 
 
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MEtrogyl Injection image
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Product introduction

MEtrogyl Injection helps prevent an infection after surgery. It is also used in the treatment of dental infections, leg ulcers, and pressure sores. This injection is administered under the supervision of a healthcare professional. It should be taken at the same time each day to get the most benefit. Your symptoms may get better after a short time but do not stop taking it until you have finished a full course of treatment, even if you feel well. If you stop taking it early, some bacteria may survive, and the infection may come back. Do not drink any alcohol while taking this medicine, and for a few days after stopping it. Otherwise, you may get unpleasant side effects like nausea, vomiting, and stomach pain.

The most common side effects of this medicine are muscle pain (myalgia), dryness in the mouth, swelling and heaviness of tongue (glossitis), and painful swelling and sores in the mouth (stomatitis). These are usually mild but let your doctor know if they bother you or last more than a few days. You can try using sugarless candies or lozenges to overcome any dryness or metallic taste in the mouth.

Before using this medicine, inform your doctor if you are allergic to any medicine or have any kidney or liver problems or any disease of the nervous system. This medicine should not be taken if you are pregnant or breastfeeding unless it is absolutely necessary and prescribed by your doctor. It may cause unusual results with certain medical tests. Therefore, tell any doctor who treats you that you are using this medicine.

Uses of MEtrogyl Injection

Benefits of MEtrogyl Injection

Treatment of Bacterial infections
MEtrogyl Injection is a versatile antibiotic medicine that can be used to treat many different infections caused by bacteria. These include infections of the blood, brain, lungs, bones, joints, urinary tract, stomach, and intestines. It can also be used to treat gum ulcers and other dental infections (abscesses), leg ulcers, and pressure sores. It works by stopping the growth of the bacteria causing the infection.

This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all bacteria are killed and do not become resistant. This medicine is generally safe to use while pregnant or breastfeeding, but you should ask your doctor.
Treatment of Parasitic infections
MEtrogyl Injection is an antibiotic medicine that helps treat many parasitic infections such as amoebic dysentery. It works by stopping the growth of parasites causing the infection. This medicine usually makes you feel better quite quickly. However, you should continue taking it as long as it is prescribed even when you feel better, to make sure that all parasites are killed and do not become resistant. This medicine is generally safe to use while pregnant or breastfeeding, but you should ask your doctor.

Side effects of MEtrogyl Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of MEtrogyl
  • Drowsiness
  • Fatigue

How to use MEtrogyl Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How MEtrogyl Injection works

MEtrogyl Injection is an antibiotic. It kills the bacteria and other microorganisms that cause infections by damaging their DNA.

Quick tips

  • MEtrogyl Injection treats infections caused by bacteria and parasites.
  • It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth.
  • Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache.
  • Inform your doctor if you have  liver disease. Your dose may need to be adjusted in severe liver disease.
  • MEtrogyl Injection treats infections caused by bacteria and parasites.
  • It may also be used to prevent infections following surgery.
  • Always take the complete course of treatment, as advised by your doctor, even if you feel better.
  • It may cause side effects like nausea, stomach upset, and a metallic taste in the mouth.
  • MEtrogyl Injection used in a high dose or for a prolonged time increases the risk of side effects such as nerve damage. Take it only as prescribed by your doctor.
  • Do not drink alcohol during or for 2-3 days after treatment with this medicine. You may develop nausea, vomiting, flushing and headache.
  • Inform your doctor if you have  liver disease. Your dose may need to be adjusted in severe liver disease.

Safety advice

Alcohol

Alcohol

UNSAFE
Consumption of alcohol with MEtrogyl Injection may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
MEtrogyl Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
MEtrogyl Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
If a single dose of MEtrogyl Injection is used, it is recommended to hold breastfeeding for 12-24 hours to allow the removal of the drug.
Driving

Driving

UNSAFE
MEtrogyl Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
MEtrogyl Injection may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.
Kidney

Kidney

SAFE IF PRESCRIBED
MEtrogyl Injection is safe to use in patients with kidney disease. No dose adjustment is recommended.
Patients undergoing kidney dialysis should take this medicine after the dialysis treatment.
Liver

Liver

CAUTION
MEtrogyl Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.
All

Interaction with drugs

Taking MEtrogyl with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Amiodarone (Oral Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Amiodarone (Injection Route)

Talk to your doctor if you notice any unusual symptoms.
Moderate

Thalidomide (Oral Route)

If concurrent use is essential, watch out for symptoms such as tingling or numbness in hands and feet, burning pain, sharp or stabbing pain, sensitivity to touch, muscle weakness or lack of coordination and consult your doctor if you experience them. They may adjust the doses as per the observations.
Moderate

Acenocoumarol (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Acenocoumarol accordingly.
Moderate

Warfarin (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly.

Frequently asked questions

Usually, MEtrogyl Injection starts working within 1 hour of its administration. However, it may take around 2-3 days to make you feel better while taking MEtrogyl Injection. If you do not experience any significant reduction in your symptoms, consult your doctor.
MEtrogyl Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from MEtrogyl Injection.
No, avoid drinking alcohol while taking MEtrogyl Injection. Moreover, you should avoid alcohol even after 3 days of finishing the complete course. Drinking alcohol can cause an unpleasant reaction (Disulfiram like reaction) with symptoms such as stomach pain, nausea, vomiting, headache, flushing or redness of the face.
Yes, MEtrogyl Injection may cause a temporary metallic taste. This metallic taste can be reduced by staying hydrated, brushing teeth after the meals and chewing sugar-free gum or mints.
Inform your doctor if you did not feel better even after completing the full course of treatment. Also, inform him/her if your symptoms are getting worse while using this medicine.

Fact Box

Chemical Class

Nitroimidazole derivative

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Antiprotozoal & Antibacterial- Nitroimidazoles

References

  1. Phillips MA, Stanley SL Jr. Chemotherapy of Protozoal Infections: Amebiasis, Giardiasis, Trichomoniasis, Trypanosomiasis, Leishmaniasis, and Other Protozoal Infections. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1428-30.
  2. Chambers HF, Deck DH. Miscellaneous Antimicrobial Agents; Disingectants, Antiseptics, & Sterilants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 877.
  3. Rosenthal PJ. Antiprotozoal Drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 912-14.
  4. Phillips MA, Stanley SL, Jr. Chemotherapy of Protozoal Infections (Metronidazole). In: Brunton LL, Lazo JS, Parker KL, editors. Goodman & Gilman's The Pharmacological Basis of Therapeutics. 11th ed. McGraw Hill; 2006. pp. 1057-60.
  5. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 905-910.
  6. Metronidazole. Thetford, Norfolk: Baxter Healthcare Ltd.; 2006 [Nov. 2017]. [Accessed 29 Mar. 2019] (online) Available from:
  7. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
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User feedback

Thrice A Day
39%
Once A Day
20%
Twice A Day
17%
Once A Month
10%
Once A Week
7%
Twice A Month
4%
Thrice A week
2%
Four Times A Day
1%
Alternate Day
1%
Bacterial infections
90%
Others
10%
Average
47%
Excellent
28%
Poor
25%
No Side Effect
38%
Dryness in mouth
25%
Nausea
12%
Headache
12%
Raised itchy skin rash
12%
With food
50%
Empty stomach
30%
With or without food
20%
Expensive
42%
Not Expensive
29%
Average
29%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: J B Chemicals and Pharmaceuticals Ltd
Address: Cnergy IT Park, 3rd floor Appa Saheb Marathe Marg, Prabhadevi, Mumbai 400025

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver MEtrogyl Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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