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Methocip 50mg Injection

Prescription Required

Overview

Introduction

Methocip 50mg Injection is a medicine used for treatment of cancer in various parts of the body such as breasts, head, neck, lungs, blood, bone, lymph, and uterus. It may be used with other medicines as part of combination therapy.

Methocip 50mg Injection is given under the supervision of a healthcare professional and should not be self-administered. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include nausea, vomiting, loss of appetite, abdominal pain, tiredness, and mouth sores. Your doctor may advise you to take folic acid to reduce some of these. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is a very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if have stomach, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, X-rays and physical examinations both before and during treatment with this medicine.

Uses of Methocip Injection

Side effects of Methocip Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Methocip

  • Nausea
  • Vomiting
  • Loss of appetite
  • Indigestion
  • Abdominal pain
  • Increased liver enzymes
  • Stomatitis (Inflammation of the mouth)

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Loss of appetite
    It is important to eat, even if you do not feel like it. You might try switching to smaller meals and frequent snacks. Try eating healthy and nutritious snacks that are high in calories and protein, such as dried fruit and nuts. It is important to drink even if you cannot eat. But, do not fill your stomach with liquid before eating. Eat when you are most hungry. Exercise such as a short walk may also increase your appetite. Talk to your doctor about possible medication or supplements if your condition does not improve.
  • Coping with Indigestion
    Try taking your medicine with a meal or snack, or shortly after eating. It might help to eat smaller and more frequent meals, and to eat and drink slowly. Avoid foods which can irritate your stomach such as carbonated soft drinks, caffeine, fatty and spicy foods, mints and citrus fruits. Quit smoking and alcohol because they increase the symptoms. Do not eat for 3 or 4 hours before going to bed. Try raising the head of your bed at night or use extra pillows. Ask your doctor or pharmacist about medicines that may help, such as antacids, if your condition does not improve.
  • Coping with Abdominal pain
    In most cases, this is mild enough to be treated at home. Try to rest and relax. Putting a heat pad or covered hot water bottle on your stomach may also help. Having a warm bath or shower can help you relax and relieve the pain. Drink plenty of clear fluids such as water and reduce your intake of coffee, tea, lemon juice or soda. Avoid alcohol and smoking as these can aggravate the pain. Eating slowly and having smaller and more frequent meals can also help. If the pain is severe, speak to your doctor. They may be able to guide you better.
  • Coping with Increased liver enzymes
    There may be no symptoms, so your doctor should carry out a blood test and give you advice. Some lifestyle changes can bring down levels of liver enzymes. In general, you will need to stop drinking alcohol or limit the amount you drink, lose weight and keep active. Drink plenty of fluids to avoid dehydration. Eat a healthy diet. Some particular foods like nuts, fatty fish, coffee, tea, olive oil, sprouts and bananas may be beneficial. Try to control stress as this can make your symptoms worse.

How to use Methocip Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Methocip Injection works

Methocip 50mg Injection is an anti-cancer medication. It works by blocking an enzyme (dihydrofolate reductase) involved in DNA synthesis in cancer cells. This slows the growth of cancer cells and eventually kills them.

Safety Advice

Alcohol
CAUTION
Caution is advised when consuming alcohol with Methocip 50mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Methocip 50mg Injection is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
UNSAFE
Methocip 50mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Methocip 50mg Injection may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Methocip 50mg Injection should be used with caution in patients with kidney disease. Dose adjustment of Methocip 50mg Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function test is advised while you are taking this medicine.
Liver
CAUTION
Methocip 50mg Injection should be used with caution in patients with liver disease. Dose adjustment of Methocip 50mg Injection may be needed. Please consult your doctor.
Use of Methocip 50mg Injection is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Methocip 50mg Injection
₹24.38/ml of Injection
Hitrex 50mg Injection
Vhb Life Sciences Inc
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Neotrexate Injection
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₹25.38/ml of Injection
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Methofast 50mg Injection
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₹29.5/ml of Injection
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Remtrex 50mg Injection
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₹36.35/ml of Injection
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Folitrax 50 Injection
Ipca Laboratories Ltd
₹49.42/ml of Injection
103% costlier

Quick Tips

  • Methocip 50mg Injection helps treat various types of cancer such as blood cancer, bone cancer, non-Hodgkin lymphoma (NHL), breast cancer, lung cancer, head and neck cancer, cervical cancer, ovarian cancer and testicular cancer.
  • Take it once a week, on the same day every week.
  • Drink plenty of liquids to stay hydrated while taking this  medication.
  • Always take folic acid as advised by your doctor. This will help lessen the side effects of this medicine.
  • It may take 6 to 8 weeks for Methocip 50mg Injection to work. Keep taking the medication as prescribed.
  • Avoid drinking alcohol while taking this medicine as it may increase the risk of side effects.
  • It can be harmful to an unborn baby. Avoid pregnancy for at least 6 months after your last dose.
  • Your doctor may get regular blood test done to monitor your kidney function, liver function and level of blood cells in your blood.

Fact Box

Chemical Class
Glutamic Acid Derivative
Habit Forming
No

Interaction with Drugs

Taking Methocip with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Rotasiil, Rotarix, RotaTeq
LIFE-THREATENING
LIFE-THREATENING
Brand(s): Abhay M, Measles, M-Vac
LIFE-THREATENING
Brand(s): Rubella
LIFE-THREATENING

Patient Concerns

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My child having JIA, i use Folitrax 50mg injection every week . How to recover
Vipul Aggarwal
Pl consult a rheumatologist for same
He has prostate cancer patient under gone surgery and biopsy report confirm it. He was taking lupride injection quarterly. but this injection is not available now. his PSA is now 14.3. .please suggest us.
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Will forward you number, you will get it from himcall him for Injection
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Do you have any questions related to Methocip 50mg Injection ?

FAQs

Q. Can Methocip cause mouth ulcers?

Yes, Methocip can cause a sore mouth and mouth ulcers as side effects in some cases. Taking folic acid along with this medicine may help in reducing the ulcers. Ask your doctor if the dose can be reduced as dose reduction may further help in reducing the ulcers.

Q. Why do I have to take folic acid with Methocip?

Folic acid is required to make new cells in the body and Methocip decreases the folic acid levels in the body. Folic acid can help reduce some of the common side effects of Methocip such as mouth ulcers, hair loss, nausea, heartburn, abdominal pain, fatigue, anemia and liver problems.

Q. Why do I need to take regular blood tests while taking Methocip?

Regular blood tests will help your doctor to check your response to Methocip and monitor you for side effects. You will need to regularly check your liver function and your blood counts (white blood cells, red blood cells and platelets). Your doctor may also order additional tests depending on the results.

Q. Can Methocip use make me more prone to infections?

Methocip may decrease the activity of your immune system. As a result, you may develop serious infections. There have been rare reports which suggest occurrence of serious lung infections with Methocip use. If you have an active infection, Methocip should be used with extreme caution.

Q. Can Methocip affect fertility?

Yes, Methocip may affect fertility in both males and females. It may cause a decrease in sperm count in males and menstrual disturbances in females. No need to worry, these effects are reversible and disappear once the therapy is discontinued.

Q. What to do if I am planning to become pregnant and my husband is taking Methocip?

You should avoid pregnancy if your husband is taking Methocip. Also, it is advised that pregnancy should be further avoided for a minimum of 3 months after the therapy as it can lead to serious fetal abnormalities.

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1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 944-46.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 887-90.
  3. Drugs.com. Methotrexate Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
A licensed vendor partner from your nearest location will deliver Methocip 50mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP48.75  Get 15% OFF
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₹41.44
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2 ml in 1 vial
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