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MMST, MBBS
Reviewed By
MD (Pharmacology), MBBS
Last updated
29 Nov 2023 | 06:56 PM (IST)

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Metaclopramide Injection

Prescription Required
Marketer
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Metaclopramide Injection is a prescription medicine used to treat nausea, vomiting, indigestion, and heartburn. It prevents the feeling of fullness during or shortly after a meal and help reduce symptoms caused by the flow of the stomach contents back into the food pipe.

Metaclopramide Injection is given by your doctor or nurse. The dose you are given will depend on your condition and how you respond to the medicine. You should take this medicine until your doctor tells you to stop. Let your doctor know about all other medications you are taking as some may affect, or be affected by this medicine.

The most common side effects are restlessness, fatigue, and weakness. Most of these are temporary and usually resolve with time. Contact your doctor straight away if you are at all concerned about any of these side effects. It also causes drowsiness, so do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid drinking alcohol while taking this medicine as it can worsen your sleepiness. This medicine may also cause diarrhea, so it is better to take plenty of fluids while taking this medicine as it may help to prevent dehydration.

Before taking this medicine, you should let your doctor know if you have liver or kidney problems. Pregnant or breastfeeding women should also consult their doctor.

Benefits of Metaclopramide Injection

In Treatment of Nausea

Metaclopramide Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting that may be caused due to some medicines or cancer treatment. This medicine helps you recover more comfortably from cancer treatments such as radiation therapy or chemotherapy. It is also effective at preventing nausea and vomiting after an operation (in adults only). The dose will depend on what you are being treated for but always take this medicine as it is prescribed.

In Treatment of Indigestion

Indigestion means discomfort of mainly the upper part of your stomach which may also have other symptoms such as stomach pain, bloating, feeling full etc. Metaclopramide Injection improves the movement of food in your stomach and gut (intestine). This relieves these symptoms and helps in proper digestion of food.

Take Metaclopramide Injection as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Do not eat within 3-4 hours of going to bed.

In Treatment of Heartburn

Heartburn is a burning feeling in your chest caused by stomach acids traveling back up towards your throat and mouth (acid reflux). Metaclopramide Injection improves the movement of food in the stomach and helps prevent heartburn.
Some simple lifestyle changes can help stop or reduce heartburn. Think about what foods trigger heartburn and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight and try to find ways to relax. Do not eat within 3 to 4 hours of going to bed.

Side effects of Metaclopramide Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Metaclopramide

  • Restlessness
  • Fatigue
  • Weakness

How to use Metaclopramide Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Metaclopramide Injection works

Metaclopramide Injection is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Safety advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Metaclopramide Injection.
Pregnancy
SAFE IF PRESCRIBED
Metaclopramide Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breast feeding
CONSULT YOUR DOCTOR
Metaclopramide Injection is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Metaclopramide Injection may cause side effects which could affect your ability to drive.
Metaclopramide Injection may cause drowsiness, dizziness, dyskinesia and dystonias which could affect the vision and may interfere with the ability to drive.
Kidney
CAUTION
Metaclopramide Injection should be used with caution in patients with kidney disease. Dose adjustment of Metaclopramide Injection may be needed. Please consult your doctor.
Liver
SAFE IF PRESCRIBED
Metaclopramide Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Metaclopramide Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Metaclopramide Injection?

If you miss a dose of Metaclopramide Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n \n

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Metaclopramide Injection helps relieve nausea, vomiting, indigestion and heartburn.
  • It is usually given as an injection into a vein or muscle by your doctor.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Metaclopramide Injection as it may cause excessive drowsiness.
  • Inform your doctor if you get watery diarrhea, fever, or stomach pain that does not go away.

Fact Box

Chemical Class
Para-Aminobenzoic Acid (PABA) Derivative
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Dopamine (D2) receptor antagonist-Prokinetic agent

Interaction with drugs

Taking Metaclopramide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Trivastal LA
Life-threatening
Brand(s): Pramipex, Pramipar, Prami
Life-threatening
Brand(s): Ropiro, Ropitor, Roparil
Life-threatening
Brand(s): Zyprima
Life-threatening

Patient concerns

arrow
Acidity,heartburn and indigestion
Dr. Aanchal Maheshwari
Ayurveda
Take avipattikar churan 1 spoon twice with water before meal, sankh vati 2 tablet twice with water
Hepatitis b + , present symptoms indigestion
Dr. Tapas Kumbhkar
Internal Medicine
Any complain of vomiting or loosmotion
arrow

User feedback


FAQs

Q. Does Metaclopramide Injection work for morning sickness?

Metaclopramide Injection can help in relieving morning sickness. However, this is not an approved indication for its use. There are other medicines also available to treat morning sickness. Consult a doctor if you need treatment for morning sickness as you should not take any medicine during pregnancy without consulting a doctor.

Q. Can I take Metaclopramide Injection with ranitidine?

Metaclopramide Injection can be taken with ranitidine. No drug-drug interactions have been reported between the two. However, interactions can occur. Talk to your doctor before taking the two medicines together.

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1325-26.
  2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Trevor AJ, editors. Basic & Clinical Pharmacology. 13th ed. New York, New York: McGraw-Hill Education; 2015. [Accessed 29 Jan. 2019] (online) Available from:External Link
  3. Drugs.com. Metoclopramide Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:External Link
  4. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 28 Mar. 2019] (online) Available from:External Link
  5. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:External Link

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013
Country of origin: India

3.6
Inclusive of all taxes
MRP3.75  4% OFF
2.0 ml in 1 vial
SOLD OUT
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