Marknif 10mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 05 Jan 2026 | 04:38 PM (IST)

Marknif 10mg Tablet is a medicine used for the treatment of hypertension (high blood pressure). It works by relaxing and widening the blood vessels, which improves blood flow and reduces the workload on the heart. It promotes better heart function and overall cardiovascular health.

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General Information

Contains

Nifedipine (10mg)

Marketer

Elixir Life Care Pvt Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Marknif 10mg Tablet may be prescribed alone or along with other medicines. Your doctor will decide the dose and duration of the treatment. Your doctor may adjust the dose depending on how you respond to this medicine and your blood pressure levels. You can take it at any time of the day, with or without food, but it is best to take it at the same time each day.

Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse. Maintaining an active lifestyle through regular exercise, managing your weight, and consuming a healthy diet will also help regulate your blood pressure. Follow your doctor’s advice while taking this medicine.

The most common side effects include fatigue, edema (swelling), dizziness, unusual heartbeat (palpitations), flushing, constipation, and headache. Consult your doctor if any of these bother you or do not go away.

Before taking it, let your doctor know if you have any heart, liver, or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. You also need to tell your doctor what other medicines you are taking, especially those used to treat high blood pressure or heart conditions. Avoid excessive alcohol intake while taking this medicine, as it can significantly decrease your blood pressure and make you feel dizzy or light-headed. You should have your blood pressure checked regularly to make sure that this medicine is working properly.

Uses of Marknif Tablet

Treatment of Hypertension (high blood pressure)

Benefits of Marknif Tablet

Treatment of Hypertension (high blood pressure)
Marknif 10mg Tablet helps manage high blood pressure (hypertension) by relaxing and widening the blood vessels, allowing blood to flow more easily. This lowers blood pressure, reduces strain on the heart, and helps prevent serious complications such as stroke, heart attack, and kidney problems. With regular use as prescribed, it helps maintain healthy blood pressure levels and supports long-term heart health.

Side effects of Marknif Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Marknif

Dizziness
Fatigue
Flushing (sense of warmth in the face, ears, neck and trunk)
Headache
Peripheral edema

How to use Marknif Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Marknif 10mg Tablet is to be taken on an empty stomach.

How Marknif Tablet works

Marknif 10mg Tablet is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow to the heart, thereby preventing any heart-related chest pain.

All substitutes for Marknif 10mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Ortinif 10mg Tablet

by Ortin Laboratories Ltd

₹0.93/tablet

same price

Quick tips

Take it at the same time every day to help you remember to take it.
A sudden drop in your blood pressure may occur, especially when you first start taking Marknif 10mg Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Marknif 10mg Tablet affects you.
Inform your doctor if you are pregnant, planning a pregnancy, or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Marknif 10mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Marknif 10mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

UNSAFE

Marknif 10mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Marknif 10mg Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Marknif 10mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Marknif 10mg Tablet in patients with liver disease.

Interaction with drugs

Taking Marknif with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Estradiol (Oral Route)

Do not use Estradiol with Nifedipine, especially if you have heart disease. If concurrent use is essential, talk to your doctor and monitor your blood pressure regularly.

Moderate

Progesterone (Oral Route)

Do not use Progesterone with Nifedipine, especially if you have heart disease. If concurrent use is essential, talk to your doctor and monitor your blood pressure regularly.

Moderate

Imatinib mesylate (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your liver function. Nifedipine may reduce efficacy of Imatinib mesylate.

Moderate

Aprepitant (Oral Route)

Watch out for symptoms such as decreased blood pressure, headache, flushing or swelling and consult your doctor if you experience them. They may adjust the dose of Nifedipine accordingly. Aprepitant may raise blood levels of Nifedipine.

Moderate

Aprepitant (Injection Route)

Frequently asked questions

Is Marknif 10mg Tablet a diuretic?

No, Marknif 10mg Tablet is not a diuretic medication. However, some evidence indicates that Marknif 10mg Tablet has a partial diuretic property which may result in increased sodium loss through urine. It is a medication which relaxes the blood vessels by directly acting on them. This helps to decrease the blood pressure of the individual. As a result, blood flows more easily and lowers blood pressure, which helps to reduce the strain or pressure on your heart.

Is Marknif 10mg Tablet bad for kidneys?

No, Marknif 10mg Tablet is not bad for kidneys. In few research studies, taking Marknif 10mg Tablet in recommended doses has in fact been shown to be beneficial for the kidneys. It is not advised to use this medicine without consulting the doctor. It should be used exactly as prescribed.

Can Marknif 10mg Tablet cause liver damage?

Yes,Marknif 10mg Tablet can cause liver damage in some cases, but this is very rare. However, some people may develop a rise in liver enzymes after taking Marknif 10mg Tablet. Let your doctor know if you notice any such changes in your recent lab tests. Do not start this medication without consulting your doctor and do inform him if you have any history of liver disease or liver damage. This is because, in case of liver damage, dose adjustment may be required.

Does Marknif 10mg Tablet affect blood sugar?

No, Marknif 10mg Tablet does not cause any change in blood sugar levels. It has been observed that Marknif 10mg Tablet has no effect on the release of insulin or change in blood sugar levels. However, before starting the medicine, inform the doctor if you are diabetic. This is done because the medicine for blood pressure is suggested accordingly when a patient is diabetic.

Can Marknif 10mg Tablet be used in pregnancy and nursing mothers?

It is advised that you should consult your doctor before taking this medicine if you are pregnant, planning to become pregnant or breastfeeding. It should be used only if prescribed by the doctor in case of pregnancy. Studies have shown significant risks to the developing baby and it is given only if the benefits are clearly more than the risks involved.

Does Marknif 10mg Tablet cause palpitations?

Yes. Marknif 10mg Tablet can cause palpitations as a side effect. However, this is usually not bothersome and resolves as you continue with the treatment. If the symptom persists for long, consult the doctor who will suggest the ways to prevent it.

Do I need to change my diet while taking Marknif 10mg Tablet?

Yes, making small changes to your diet can help your medicine work better. You must take a low sodium and low-fat diet, and adhere to the lifestyle changes as advised by your doctor. You should also avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Marknif 10mg Tablet.

My blood pressure is now controlled. Can I stop taking Marknif 10mg Tablet now?

No, do not stop taking it on your own as it may worsen your condition. You should take Marknif 10mg Tablet in the dose and duration advised by your doctor. Consult your doctor for any query or dose modification.

Fact Box

Chemical Class

Dihydropyridine carboxylic acid derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Calcium Channel Blockers- Dihydropyridines (DHP)

Related lab tests

Kidney Function Test

References

Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 757-58.
Opie LH. Calcium Channel Blockers. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. pp. 84-86.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 978-79.
Nifedipine. New York, New York: Pfizer Labs; 2013. [Accessed 19 Mar. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 19 Mar. 2019] (online) Available from:
National Health Sciences. Nifedipine. [Last Reviewed: 18 Feb. 2022]. [Accessed 25 Jul. 2023] (online) Available from:
Khan KM, Patel JB, Schaefer TJ. Nifedipine. [Updated 2023 May 23]. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2023. [Accessed 25 Jul. 2023] (online) Available from:
Central Drugs Standard Control Organisation. Nifedipine. [Accessed 25 Jul. 2023] (online) Available from:
Nifedipine. Ahmedabad, Gujarat: Zydus Lifesciences Ltd.; 2024 [Accessed 5 Jan. 2026] (online). Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Elixir Life Care Pvt Ltd
Address: No: 260, Sydenhams Road, Choolai, Chennai - 600112, India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Marknif 10mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Marknif Tablet

Benefits of Marknif Tablet

Side effects of Marknif Tablet

How to use Marknif Tablet

How Marknif Tablet works

All substitutes for Marknif 10mg Tablet

Ortinif 10mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Estradiol (Oral Route)

Progesterone (Oral Route)

Imatinib mesylate (Oral Route)

Aprepitant (Oral Route)

Aprepitant (Injection Route)

Frequently asked questions

Is Marknif 10mg Tablet a diuretic?

Is Marknif 10mg Tablet bad for kidneys?

Can Marknif 10mg Tablet cause liver damage?

Does Marknif 10mg Tablet affect blood sugar?

Can Marknif 10mg Tablet be used in pregnancy and nursing mothers?

Does Marknif 10mg Tablet cause palpitations?

Do I need to change my diet while taking Marknif 10mg Tablet?

My blood pressure is now controlled. Can I stop taking Marknif 10mg Tablet now?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Kidney Function Test

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests