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Nifedipine is used in the treatment of increased blood pressure and angina.

How it works

Nifedipine is a calcium channel blocker. It blocks the action of calcium on the heart and blood vessels. This lowers the blood pressure, abnormally fast heartbeat and reduces strain on the heart following a heart attack.

Common side effects

Fatigue, Ankle swelling, Sleepiness, Flushing (sense of warmth in the face, ears, neck and trunk), Headache, Nausea, Dizziness, Palpitations, Edema, Abdominal pain

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Expert advice

  • Notify your doctor if you are planning to become pregnant.
  • Nifedipine can cause swelling in the ankle or feet. Notify your doctor if it bothers you.
  • The missing dose of the Nifedipine can cause your blood pressure to go up suddenly, which raises the risk of heart attack and stroke. You can take the medicine at the same time every day to avoid forgetting it.
  • You may get a headache that lasts for a short time, after starting Nifedipine. This should become less noticeable after a few days.
  • Nifedipine may cause dizziness in the first few days of starting the treatment.
  • Swelling, bleeding or tenderness of gums may occur after starting the treatment. Brushing and flossing of teeth carefully and regularly may prevent this.

Frequently asked questions



Is nifedipine safe?
Nifedipine is relatively safe if used as recommended. In case of any side-effects, consult your doctor


Is Nifedipine a nitrate/beta-blocker/ACE inhibitor/tocolytic?
No. Nifedipine is not a nitrate, beta-blocker, or an ACE inhibitor. It is a calcium channel blocker


What is Calcigard/Nicardia/Dipin used for?
Calcigard, Nicardia, Dipin are examples of a few brands containing nifedipine and used for treating high blood pressure, chest-pain and Reynaud's phenomenon

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Can I take aspirin/Tylenol/Benadryl/Viagra/ Tums/Sudafed with nifedipine?
Nifedipine can be taken with Tylenol (paracetamol), Sudafed (pseudoephedrine) and Benadryl. Taking Viagra (sildenafil) may increase the blood pressure lowering effect of nifedipine. Taking aspirin may increase the blood pressure. Tums (calcium carbonate) may decrease the effect of nifedipine. Consult your doctor before use


Does nifedipine cause migraine/constipation/insomnia/bradycardia/cough/weight gain/urination/changes in heart rate?
Nifedipine may cause migraine, constipation, insomnia or bardycardia (slow heart rate). There is no evidence of nifedipine causing cough or weight changes. If you notice such symptoms, please consult your doctor


Is nifedipine a narcotic or tocolytic?
No. Nifedipine is a non-narcotic/ uncontrolled/nonaddictive drug. Nifedipine is used as tocolytic (to delay preterm birth).


Can I take nifedipine with pseudoephedrine?
Nifedipine can be taken with pseudoephedrine. No drug-drug interactions have been reported between the two. However, this does not mean that interactions cannot occur. Please consult your doctor before taking the two medicines together.


Can I take nifedipine with naproxen?
Nifedipine can be taken with naproxen. No drug-drug interactions have been reported between the two. However, interactions can occur. Talk to your doctor before taking the two medicines together.

Content on this page was last updated on 18 April, 2017, by Dr. Varun Gupta (MD Pharmacology)