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18 Feb 2020 | 05:25 PM (IST)
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Mamazol 2.5mg Tablet


Overview

Introduction

Mamazol 2.5mg Tablet is an aromatase inhibitor. It is used in the treatment of breast cancer in women who have gone through menopause. It is used before surgery to reduce tumor or after surgery to prevent it from coming back.

Mamazol 2.5mg Tablet is also helpful in the treatment of infertility. It can be taken with or without food, but take it at the same time to get the most benefit. It should be taken as your doctor's advice. The dose and how often you take it depends on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. Swallow the tablets whole with a drink of water. You should take this medicine for as long as it is prescribed for you.

The most common side effects of medicine include hot flashes, fatigue, increased sweating, and  Increased level of cholesterol (hypercholesterolaemia).  If these bother you, or appear serious, let your doctor know. There may be ways of reducing or preventing them. Some side effects may mean you should inform your doctor immediately include vaginal bleeding, swelling of face, rash, and thinning of bones.

Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or you had a history of osteoporosis (thinning or wasting of bones).  Your doctor should also know about all other medicines you are taking as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D level or bone density before and thereafter treatment.

Side effects of Mamazol Tablet

Common
  • Increased cholesterol level in blood
  • Fatigue
  • Increased sweating
  • Increased cholesterol level in blood

How to use Mamazol Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Mamazol 2.5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Mamazol Tablet works

Mamazol 2.5mg Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow. In addition, it is also useful in infertility whereby it increases the release of certain hormones to stimulate the release of eggs from the ovaries.

Safety Advice

Alcohol
SAFE
Consuming alcohol with Mamazol 2.5mg Tablet does not cause any harmful side effects.
Pregnancy
UNSAFE
Mamazol 2.5mg Tablet is highly unsafe to use during pregnancy. Seek your doctor's advice as studies on pregnant women and animals have shown significant harmful effects to the developing baby.
Breastfeeding
UNSAFE
Mamazol 2.5mg Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Mamazol 2.5mg Tablet may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
SAFE IF PRESCRIBED
Mamazol 2.5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Mamazol 2.5mg Tablet is recommended.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Mamazol 2.5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Mamazol 2.5mg Tablet may be needed. Please consult your doctor.

What if you forget to take Mamazol Tablet?

If you miss a dose of Mamazol 2.5mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Mamazol 2.5mg Tablet
₹12.0/Tablet
Fempro Tablet
Cipla Ltd
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save 48%
Letrohope 2.5 Tablet
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Stimufol 2.5mg Tablet
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₹32.4/Tablet
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Letroz Tablet
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₹40.35/Tablet
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Letoval Tablet
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₹40.35/Tablet
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Quick Tips

  • You have been prescribed Mamazol 2.5mg Tablet for the treatment of breast cancer or infertility due to anovulation.
  • It can be taken with or without food.
  • Do not drive or do anything requiring concentration until you know how Mamazol 2.5mg Tablet affects you.
  • It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
  • Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Mamazol 2.5mg Tablet can alter their levels.
  • Do not take Mamazol 2.5mg Tablet if you are pregnant or breastfeeding 

Interaction with Drugs

Taking Mamazol with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Evaride, Estratag, Lanadiol
LIFE-THREATENING
Brand(s): E Gen, Lynoral, Veronica
LIFE-THREATENING
Brand(s): Tibomax, Sibolone, Maxtib
LIFE-THREATENING
Brand(s): Vagimoist
LIFE-THREATENING

Patient Concerns

arrow
Breast pain not able to sleep already take test no cancer but pain
Dr. Megha Tuli
Obstetrics and Gynaecology
Hi Rajeshwari. Breast pain can be due to hormonal changes as well. Please visit a gynaecologist in your area for a thorough evaluation.
If any symtom of brest cancer if have whats the cure
Dr. Sanjay Singh Rai
Medical Oncology and Hematology
First is confirmation of breast cancerChance of cure depends on stage of cancer
arrow
Do you have any questions related to Mamazol 2.5mg Tablet ?

User Feedback


FAQs

Q. Why have I been prescribed Mamazol?

Mamazol is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy. It is also used to treat infertility caused due to anovulation (during menstrual cycle egg cell from ovaries is not released).

Q. How does Mamazol work?

Mamazol is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent the cancer from growing.

Q. For how long should I take Mamazol?

If the breast tumor is in advanced stage or has spread to other parts of the body, it is recommended that you continue taking Mamazol till the tumor shows progression. In cases where Mamazol is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Mamazol followed by 3 years of tamoxifen.

Q. If I am taking irbesartan to control my blood pressure, can I take Mamazol?

Yes, you can take irbesartan and Mamazol together. However, be careful and keep a regular check on your blood pressure since Mamazol may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.

Q. Does Mamazol affect vision?

Although it is very uncommon but Mamazol may cause cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.

Q. My friend who is taking Mamazol often sweats a lot. Is it because of Mamazol?

This could be a sign of hot flushes which is a very common side effect of Mamazol. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Mamazol. However, in some people the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.

Q. What are the serious side effects of Mamazol?

The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Mamazol include stroke, angina, heart attack, blood clotting, cataract, osteoporosis and severe skin reactions.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
  2. Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
  3. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
  4. Drugs.com. Letrozole. [Accessed 03 Apr. 2019] (online) Available from:External Link
  5. Letrozole. Barnstaple, Devon: Accord-UK Ltd.; 2009 [revised 20 Nov. 2017]. [Accessed 25 Jan. 2019] (online) Available from:External Link
  6. Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:External Link
  7. Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
KHANDELWAL LABORATORIES PVT. LTD, 79/87 D.LADPATH, MUMBAI 400 033, INDIA
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