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Last updated
23 Jan 2026 | 10:15 AM (IST)

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Macrogen 400mg Injection

rx_imgPrescription Required
SALT COMPOSITION
Storage
Store below 30°C

Product introduction

Macrogen 400mg Injection is used to prevent infections after chemotherapy. It is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Macrogen 400mg Injection is given as an injection by a qualified medical professional. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include bone pain, decreased blood pressure, nausea, and vomiting. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. You might be asked for regular tests done to check the number of blood cells in your blood while you are taking this medicine.

Before taking it, tell your doctor if you have heart disease, breathing problems, swelling, or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your healthcare team know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy.


Uses of Macrogen Injection

  • Prevention of Infections after chemotherapy

Benefits of Macrogen Injection

In Prevention of Infections after chemotherapy

Macrogen 400mg Injection increases the production of white blood cells by stimulating the immune system in our body. White blood cells are those cells that help us to fight infections. This medicine is really effective and must be used under medical supervision. Avoid being in crowds and wash your hands often to prevent any infections. Have plenty of fluids, unless otherwise advised by the doctor not to.

Side effects of Macrogen Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Macrogen

  • Flu-like symptoms
  • Fever
  • Diarrhea
  • Feeling of discomfort
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Bone pain
  • Decreased blood pressure
  • Nausea
  • Vomiting
  • Breathlessness
  • Rash

How to use Macrogen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Macrogen Injection works

Macrogen 400mg Injection is a growth factor that stimulates the bone marrow to produce white blood cells. These cells protect the body against infections.

Safety advice

Alcohol
CAUTION
Alcohol should be used with caution while taking Macrogen 400mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
The safety of Macrogen 400mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding
SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving
CONSULT YOUR DOCTOR
It is not known whether Macrogen 400mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney
CAUTION
Macrogen 400mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver
SAFE IF PRESCRIBED
Macrogen 400mg Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

What if you forget to take Macrogen Injection?

If you miss a dose of Macrogen 400mg Injection, contact your doctor as soon as possible. They will advise you on how to proceed, which may include rescheduling the missed dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Macrogen 400mg Injection is given as an injection under the supervision of a doctor only.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your blood cell count (CBC), liver and kidney function.

Fact Box

Chemical Class
Peptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Granulocyte-Macrophage Colony Stimulating Factor (GM-CSF)

Interaction with drugs

Taking Macrogen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Cladribine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marro... More
Do not consume Clofarabine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marr... More
Do not consume Capecitabine from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone mar... More
Do not consume Carboplatin from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the bone marr... More
Do not consume Doxorubicin (Plain) from 1 day before until 1 day after taking Molgramostim. Please consult your doctor. Concurrent use may cause a decrease in the ability of the b... More

Patient concerns

Plz check the report and reply She is my wife report one of hospital where operated the tumot operation and one of from delhi srl and last one from tmh mumbai After the diagnosis docror advice rediation now 1 st rediation therapy is finished and doctor giving now nublast 250mg tab So plz check the report and tell me as per the tata memorial final report what is the condition for patient She can live normal life or she can dead in ahead Doctor tells with my family she can live with treatment more than 1 to 2 years Is it right or wrong
Dr. Vijay Sharnangat
Medical Oncology and Hematology
You are on right treatmentAfter completion of radiation therapy you need to take chemotherapyThat tablet is the chemotherapy
What is symptomatic after chemotherapy for metastatic spine
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Back pain is main symptom which you can get after disease progression

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Thomas X. New emerging applications of molgramostim in acute myeloid leukaemia. Expert Opin Drug Metab Toxicol. 2008 Jun;4(6):795-806. [Accessed 29 Dec. 2025]. Available from: External Link

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205
Country of origin: India

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We do not facilitate sale of this product at present

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