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Macfe Injection

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 25 Nov 2025 | 03:05 PM (IST)
Macfe Injection is an iron replacement medicine. It is used to treat a type of anemia where you have too few red blood cells because you have too little iron in your body (iron-deficiency anemia). Iron is needed to produce the red blood cells that carry oxygen around your body.
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General Information

Contains

Iron Sucrose (20mg/ml)

Marketer

Mactif Pharma

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.
The content is shown in English
Macfe Injection image
Macfe Injection image
Macfe Injection image
Macfe Injection image

Product introduction

Macfe Injection is given by slow infusion (drip) into a vein by your doctor or nurse. Your doctor will decide the dose you need and how many injections you should have to improve your anemia. It will also help to eat a well-balanced diet that has enough iron. Good sources of iron include pulses (dal), green leafy vegetables like spinach, beans, eggs, dry fruits, and non-vegetarian foods.

The most common side effects include altered taste, hypertension (high blood pressure), nausea, and injection site reactions (such as pain, redness, and swelling). Some people may develop a temporary fall in blood pressure (hypotension) if this medicine is given too rapidly. Your doctor will also monitor you for signs of an allergic reaction such as breathlessness, dizziness, feeling uneasy, hives, swelling of face, tongue, and throat, etc. while this medicine is being given. If you are bothered by them or they go on for longer, talk to your doctor or nurse.

You should not have this medicine if your anemia is not caused by a lack of iron. Before taking it, tell your doctor if you have rheumatoid arthritis, asthma or other allergies, high blood pressure, or liver problems. This may affect your treatment. It is not known whether this medicine is safe for use if you are pregnant or breastfeeding so please take advice from your doctor. You will have tests to check your blood cells and iron levels, monitor your progress and check for side effects. It may be advisable to limit alcohol during treatment.

Uses of Macfe Injection

Benefits of Macfe Injection

Iron deficiency anemia
Anemia is a condition where your body does not have enough red blood cells to carry oxygen around your body. If you do not have enough iron from the foods you eat (because of poor nutrition or poor absorption of the mineral), your body will produce fewer red blood cells and can cause anemia. Macfe Injection is an iron replacement product. It can boost your levels of red blood cells and reduce the symptoms of anemia such as tiredness and weakness. This medicine is given as an injection by a doctor or nurse. You should not have this medicine if your anemia is not caused by a lack of iron.

Side effects of Macfe Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Macfe
  • Taste change
  • Injection site reactions (pain, swelling, redness)
  • Nausea
  • Decreased blood pressure
  • High blood pressure

How to use Macfe Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Macfe Injection works

Macfe Injection is an anti-anemic medication. It replenishes the iron stores in your body. Iron is vital for the formation of new red blood cells and hemoglobin, a substance that gives these cells the ability to transport oxygen.

Quick tips

  • Macfe Injection is prescribed for the treatment of iron deficiency anemia.
  • It is given as a slow injection into veins or as drip under the supervision of a doctor.
  • You may be asked for regular monitoring of iron level in blood while taking this medicine.
  • It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you.
  • Inform your doctor if notice shortness of breath, swelling of face, low blood pressure, itching, or rash. 
     

Safety advice

Alcohol

Alcohol

UNSAFE
It is unsafe to consume alcohol with Macfe Injection
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Macfe Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

UNSAFE
Macfe Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Macfe Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

CAUTION
Macfe Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Macfe Injection is used to regulate hemoglobin levels in the human body. It is usually given to patients who have iron deficient anemia or iron deficiency. The doctor may suggest using this medicine till the hemoglobin level becomes normal. Do consult your doctor to understand the usage of this medicine properly.
Macfe Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Macfe Injection.
Yes, Macfe Injection can be taken for iron deficiency anemia and iron deficiency. However, its use for other types of anemia is not recommended. Take Macfe Injection in the dose and duration advised by your doctor.
You can consume food items that are rich in iron content (like red meat, pork, poultry and seafood). Other food items which contain rich iron content include beans, dark green leafy vegetables (like spinach), peas, dried fruit (raisins and apricots), iron-fortified cereals, breads and pastas. You can also try iron supplements (tablets or capsules) available at pharmacy stores for iron deficient anemia.
Yes, Macfe Injection can increase weight. Exercise regularly and take a balanced diet that includes whole grains, fresh fruits, vegetables and fat-free products. You should consult your doctor if you need any further help to manage your weight.

Fact Box

Chemical Class

O- glycosyl compounds

Habit Forming

No

Therapeutic Class

GYNAECOLOGICAL

Action Class

Hemopoietic Agents
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Mactif Pharma
Address: no. 113, 1st floor, tirupati complex, krishna nagar, ahmedabad-380001, gujarat, india / LG/7 Kautilya apartment Near Hetvi Tower Anandnagar Road Ahmedabad 380015

Vendor Details

Country of origin: India
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