Loxipen 400mg Tablet

Lomefloxacin (400mg)

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Loxipen 400mg Tablet is an antibiotic, used in the treatment of bacterial infections. It is also used in treating infections of the urinary tract, nose, throat, skin and soft tissues and lungs (pneumonia). It cures the infection by stopping the further growth of the causative microorganisms.

Written By Dr. Anuj Saini, MMST, MBBS,
Reviewed By Dr. Mekhala Chandra, MD, MBBS,
Last updated on 25 Nov 2025 | 03:05 PM (IST)

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Gurgaon

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General Information

Contains

Lomefloxacin (400mg)

Marketer

Morepen Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Loxipen 400mg Tablet should be used in the dose and duration as advised by your doctor. It may be taken with or without food, preferably at a fixed time. Avoid taking antacids containing aluminum or magnesium within 2 hours before or 2 hours after you take this medicine. Taking antacids, sucralfate, or vitamin or mineral supplements too close to a dose of this medicine, can greatly decrease the effects of the antibiotic. Do not skip any doses and finish the full course of treatment even if you feel better. You should not take a double dose to make up for a missed dose. Simply take the next dose as planned.

You may have a headache, dizziness, nausea, and constipation as side effects of this medicine. These are usually temporary and resolves on its own, but please consult your doctor if it bothers you or persists for a longer duration. Diarrhea may also occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.

You should not take this medicine if you are allergic to any of its ingredients. Special care should be taken in people with kidney problems while taking this medicine.

Uses of Loxipen Tablet

Bacterial infections

Benefits of Loxipen Tablet

Bacterial infections
Loxipen 400mg Tablet is an antibiotic medicine which can be used to treat many different infections caused by bacteria. It stops the growth of the bacteria causing the infection and clears the infection. Take it for as long as prescribed by the doctor and avoid skipping doses. This will make sure that all bacteria are killed and they do not become resistant.

Side effects of Loxipen Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Loxipen

Headache
Dizziness
Nausea
Constipation
Diarrhea

How to use Loxipen Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Loxipen 400mg Tablet may be taken with or without food.

How Loxipen Tablet works

Loxipen 400mg Tablet is an antibiotic medicine to be taken by mouth. It works by stopping the action of a bacterial enzyme called DNA-gyrase. This prevents the bacterial cells from dividing and repairing, thereby killing them.

Quick tips

Your doctor has prescribed Loxipen 400mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Loxipen 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
Your doctor has prescribed Loxipen 400mg Tablet to cure your infection and improve symptoms.
Do not skip any doses and finish the full course of treatment even if you feel better.
Discontinue Loxipen 400mg Tablet and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Safety advice

Alcohol

SAFE

Consuming alcohol with Loxipen 400mg Tablet does not usually cause any harmful side effects.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Loxipen 400mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Loxipen 400mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

SAFE

Loxipen 400mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Loxipen 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Loxipen 400mg Tablet in patients with liver disease.

Interaction with drugs

Taking Loxipen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Lomefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Lomefloxacin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Lomefloxacin. Please consult your doctor. Lomefloxacin may reduce the efficacy of Cholera Vaccine (Inactivated).

Moderate

Zolmitriptan (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Lomefloxacin may raise blood levels of Zolmitriptan.

Moderate

Acenocoumarol (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Acenocoumarol accordingly.

Moderate

Warfarin (Oral Route)

Your doctor may frequently monitor your blood clotting time and adjust the dose of Warfarin accordingly.

Frequently asked questions

Can the use of Loxipen 400mg Tablet increase the risk of muscle damage?

Yes, use of Loxipen 400mg Tablet is known to increase the risk of muscle damage, commonly in the ankle (achilies tendon). Muscle damage can happen in people of all ages who take Loxipen 400mg Tablet. Inform your doctor if you feel any kind of muscle pain while using this medicine.

Fact Box

Chemical Class

Quinoline carboxylic acids

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Bacterial DNA Replication Inhibitors- Quinolones/ Fluroquinolones

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 794-95.
PubChem. Lomefloxacin. [Accessed 01 Apr. 2019] (online) Available from:
ScienceDirect. Lomefloxacin. [Accessed 01 Apr. 2019] (online) Available from:
Lomefloxacin. Jan. 2005. [Accessed 01 Apr. 2019] (online) Available from:
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 01 Apr. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 01 Apr. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Morepen Laboratories Ltd
Address: 409, Antriksh Bhawan, 22 Kasturba Gandhi Marg, New Delhi - 110 001 / AG-82 Basement Ground Floor, Sanjay Gandhi Transport Nagar, North West Delhi-110042

Vendor Details

Country of origin: India

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Why we need a prescription?

Loxipen 400mg Tablet

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Loxipen Tablet

Benefits of Loxipen Tablet

Side effects of Loxipen Tablet

How to use Loxipen Tablet

How Loxipen Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Zolmitriptan (Oral Route)

Acenocoumarol (Oral Route)

Warfarin (Oral Route)

Frequently asked questions

Can the use of Loxipen 400mg Tablet increase the risk of muscle damage?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Peripheral Smear Examination

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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