Liofen 50mg Injection

Baclofen (50mg)

Genuine

Authenticity Assured

Prescription

required

Liofen 50mg Injection is a muscle relaxer. It is used to treat muscle symptoms such as rigidity, tension, and stiffness that may occur due to various conditions such as cerebral palsy, multiple sclerosis, motor neuron disease, or injury to the head, brain or spine.

Written By Dr. Lipika Khurana, PGDHHM, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 23 Jan 2026 | 10:15 AM (IST)

₹123 MRP ₹13912% off

We do not facilitate sale of this product at present

Gurgaon

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 75 with minimum cashback of Rs. 15

Earn cashback up to Rs.75 with Amazon Pay Later

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Pay with Amazon Pay Balance and get cashback up to Rs. 75 with minimum cashback of Rs. 15

Earn cashback up to Rs.75 with Amazon Pay Later

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback on minimum transaction of Rs.599/- with Mobikwik UPI.

Flat Rs.150 on a Min Transaction of Rs.1000.

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

General Information

Contains

Baclofen (50mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Liofen 50mg Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.

The most common side effects of this medicine include injection site reactions (such as pain, redness, and swelling), fatigue, drowsiness, weakness, and dizziness. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.

Before using it, you should let your doctor know if you have ever had seizures, stomach ulcers, diabetes, problems with your heart, liver, or kidneys, etc. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.

If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.

Uses of Liofen Injection

Muscle relaxation

Benefits of Liofen Injection

Muscle relaxation
Liofen 50mg Injection is a muscle relaxant that is used to relieve rigidity, inflammation, and swelling in conditions that affect skeletal muscles. It works by blocking chemical messengers in the brain that are responsible for such symptoms. It effectively relieves muscle stiffness or spasm, thereby improving muscle movement.

Take it as it is prescribed to get the most benefit. Do not take more or for longer than needed as that can be dangerous. In general, you should take the lowest dose that works, for the shortest possible time. This will help you to go about your daily activities more easily and have a better, more active, quality of life.

Side effects of Liofen Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Liofen

Dizziness
Convulsion
Nausea
Headache
Sedation
Hypotension (low blood pressure)
Hypotonia (decreased muscle tone)
Agitation
Constipation
Increased white blood cell count
Chills
Urinary retention

How to use Liofen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Liofen Injection works

Liofen 50mg Injection is a muscle relaxant. It works on the brain and spinal cord to relieve muscle stiffness or spasm maintaining the strength of the muscles. This relieves pain and improves movement of muscles.

Quick tips

Liofen 50mg Injection provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Liofen 50mg Injection may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Liofen 50mg Injection as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
Liofen 50mg Injection provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system.
Take it with or after food or a glass of milk.
Liofen 50mg Injection may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
Avoid consuming alcohol when taking Liofen 50mg Injection as it may cause excessive drowsiness.
Inform your doctor if you are pregnant, planning to conceive or breastfeeding.
Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Liofen 50mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Liofen 50mg Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Liofen 50mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Liofen 50mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.

Kidney

CAUTION

Liofen 50mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Liofen 50mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Liofen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Tramadol (Injection Route)

If concurrent use is essential, your doctor may monitor your respiratory and cardiovascular functions along with your overall treatment and adjust the doses as per the observations.

Moderate

Trihexyphenidyl (Injection Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Clozapine (Oral Route)

Watch out for symptoms such as dry mouth, increased heart rate, urination difficulties, constipation, loss of appetite or nausea and consult your doctor if you experience them.

Moderate

Trihexyphenidyl (Oral Route)

Talk to your doctor if you notice any unusual symptoms.

Moderate

Tramadol (Oral Route)

If concurrent use is essential, your doctor may monitor your respiratory and cardiovascular functions along with your overall treatment and adjust the doses as per the observations.

Frequently asked questions

Can Liofen 50mg Injection make you sleepy?

Yes, Liofen 50mg Injection can cause sleepiness. It can make a person dizzy due to its sedative effect. It can also affect vision and therefore you should avoid driving and using heavy machinery until and unless you know how Liofen 50mg Injection affects you.

Is Liofen 50mg Injection a narcotic?

No, Liofen 50mg Injection is not a narcotic. It is a muscle relaxant. It does not have abuse potential. Liofen 50mg Injection may cause side effects which include drowsiness, euphoria, and dysphoria. Hence, it should not be used with medicines that cause similar side effects like pain-relieving opiates.

Does Liofen 50mg Injection help anxiety?

Though Liofen 50mg Injection is not approved to treat anxiety disorders, it has been observed in some studies that it is effective in treating stress which occurs after a trauma.

Can I take Liofen 50mg Injection if I have a liver problem?

If you have a liver problem then you need to be cautious while taking Liofen 50mg Injection. This is because the medicine may increase the production of liver enzymes. Hence, regular laboratory examination of liver enzymes is required while taking this medicine as advised by your doctor.

Does Liofen 50mg Injection have any effect on kidneys?

Liofen 50mg Injection may cause side effects in patients with normal kidney function which include excessive day time urination (pollakiuria), burning sensation while urinating (dysuria), and loss of bladder control (urinary incontinence). Generally, a lower dose of this medicine is prescribed if a person has abnormally functioning kidneys or if a person is on dialysis.

How long does Liofen 50mg Injection take to work?

Liofen 50mg Injection starts working after 0.5-1 hours when the injection is given as a bolus (a large amount of medication is infused at a time). The effect of the medicine can be observed after 4 hours of administration which will last for 4-8 hours. However, if it is given as a continuous infusion then it takes about 6-8 hours to show its effect which reaches its peak within 24 to 48 hours.

What’s the most important thing that I should know about Liofen 50mg Injection?

Suddenly discontinuing intrathecal (given in spinal fluid) Liofen 50mg Injection injection may cause serious side effects such as high fever, severe muscle spasm, and rigidity. These side effects can progress to dangerous consequences and can even lead to death. Therefore, the medicine should be gradually reduced.

Fact Box

Chemical Class

Gamma Amino Acids Derivative

Habit Forming

Therapeutic Class

PAIN ANALGESICS

Action Class

Centrally Acting Skeletal Muscle Relaxants

References

White PF, Katzung BG. Skeletal Muscle Relaxants. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 463.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 121-23.
Chaves RG, Lamounier JA. Breastfeeding and maternal medications. Baclofen Pregnancy and Breastfeeding Warnings. [Accessed 02 Apr. 2019] (online) Available from:
Baclofen [Prescribing Information]. Plainsboro, NJ: Advagen Pharma Ltd.; 2023. [Accessed 09 Jun, 2023] (online) Available from:

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205 || Plot no 107/108,Namli block , Ranipool, East Sikkim 737135

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Liofen 50mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Liofen Injection

Benefits of Liofen Injection

Side effects of Liofen Injection

How to use Liofen Injection

How Liofen Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Tramadol (Injection Route)

Trihexyphenidyl (Injection Route)

Clozapine (Oral Route)

Trihexyphenidyl (Oral Route)

Tramadol (Oral Route)

Frequently asked questions

Can Liofen 50mg Injection make you sleepy?

Is Liofen 50mg Injection a narcotic?

Does Liofen 50mg Injection help anxiety?

Can I take Liofen 50mg Injection if I have a liver problem?

Does Liofen 50mg Injection have any effect on kidneys?

How long does Liofen 50mg Injection take to work?

What’s the most important thing that I should know about Liofen 50mg Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests