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Limus 1 mg Tablet

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Claris Lifesciences Ltd

Composition for Limus 1 mg Tablet

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Primary uses of Limus 1 mg Tablet

Prevention of kidney transplant rejection
MRP
1365
₹136.5/Tablet
10 tablets in 1 strip
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Medicine Overview of Limus Tablet

uses

Uses of Limus Tablet

Limus 1 mg Tablet is used to prevent prevention of kidney transplant rejection.
uses

Limus Tablet side effects

Common

Side Effects of Limus are Increased risk of infection, Mouth ulcer, Vomiting, Nausea, Decreased blood cells (red cells, white cells, and platelets), Stomach upset, Protein in urine.

uses

How to use Limus Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Limus 1 mg Tablet may be taken with or without food, but it is better to take it at a fixed time.

How Limus Tablet works

Limus 1 mg Tablet is an immunosuppressant. It works by suppressing your body’s immune response following transplant of an organ (eg. liver, kidney, heart). This helps your body to accept the new organ as if it were your own.

In Depth Information on Limus Tablet

Expert advice for Limus Tablet

  • You may be frequently monitored for renal function during concomitant administration of sirolimus and ciclosporin.
  • Sirolimus increase risk of infection and the risk of developing certain types of cancer (e.g., lymphoma, skin cancer). Seek immediate medical attention if you notice signs of infection (e.g., persistent sore throat, chills, and fever), any changes in the appearance or size of a mole, night sweats, unusual growths or lumps, or unusual tiredness or weakness.
  • Avoid use of live vaccines during treatment as the vaccination may be less effective when taking sirolimus.
  • Use effective methods of contraception during sirolimus therapy and for 12 weeks after sirolimus has been stopped.
  • Consult your doctor if you develop any liver problems, kidney problems, high cholesterol or triglycerides, low blood platelet levels, diabetes or high blood sugar, or lung or breathing problems or if you are considered to be at high risk for rejection, such as if you had a previous transplant that was lost to rejection.
  • Limit the exposure to sunlight and UV light by covering your skin with clothing and using a sunscreen with a high protection factor because of the increased risk for skin cancer, when receiving sirolimus.
  • Take sirolimus at the same time in relation to ciclosporin, and consistently with or without food, as its blood levels will be monitored.
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Limus Tablet related warnings
Special precautions for Limus Tablet
Alcohol
Interaction with alcohol is unknown. Please consult your doctor.
Pregnancy
WEIGH RISKS VS BENEFITS
Limus 1 mg Tablet may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Lactation
CAUTION
Limus 1 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Driving
SAFE
Limus 1 mg Tablet does not usually affect your ability to drive.
Kidney
SAFE
Limus 1 mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Limus 1 mg Tablet is recommended.
Liver
Limus 1 mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment of Limus 1 mg Tablet may be needed. Please consult your doctor.
Dose adjustment is not recommended in patients with mild to moderate liver disease.

Patient Concerns

Frequently asked questions about Limus Tablet

Frequently asked questions about Sirolimus

Limus is not dialyzable to significant extent. i.e. it will not be eliminated after dialysis.
Limus is not a calcineurin inhibitor, but it has a similar suppressive effect on the immune system
Limus is a cytotoxic agent
The Limus-eluting stent is a metal stent coated with 140 µg/cm2 of Limus blended with synthetic polymers. After stent implantation, Limus is slowly released causing localized inhibition of growth of smooth muscle cells in the wall of the blood vessel in which it is implanted over a period of about 1 month
Limus causes hair loss
Limus alters certain body pathways to increase lipid/fat synthesis by the liver, thereby causing hyperlipidemia.

Severely interacts with other drugs like

Taking Limus with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
LIFE-THREATENING
Medicines with composition Rubella vaccine (Live): Rubella, R-VAC
Limus with Rifampicin
LIFE-THREATENING
Medicines with composition Rifampicin: Monocin, Rifacept, R-Cin, Montomycin
LIFE-THREATENING
Medicines with composition Varicella Vaccine (live) attenuated: Biovac V
Limus with Voriconazole
LIFE-THREATENING
Medicines with composition Voriconazole: Vosicaz, Vorizol, Voraze, Rextro, Vhope, Vonaz, Vocozo, Voritek, Voritrop, Vorifit, Vorzu
LIFE-THREATENING
Medicines with composition Bacillus Calmette-Guerin high strength: Oncovac, SII-Onco-BCG
Limus with Spiramycin
LIFE-THREATENING
Medicines with composition Spiramycin: Spiramycin, Macromycin, Spiratox
Medicines with composition Inactivated Japanese Encephalitis virus protein: Jeev
Limus with Erythromycin
LIFE-THREATENING
LIFE-THREATENING
Medicines with composition Rotavirus vaccine (live attenuated,oral): Rotarix
Limus with Clarithromycin
LIFE-THREATENING
Medicines with composition Clarithromycin: Clarimac, Klarim, Cloff, Clarital, Truclar, Claricin, Bioclar, Claribid, Klarcid, Clarie, C Cin
Limus with Benidipine
SERIOUS
Medicines with composition Benidipine: Caritec
Limus with S-Amlodipine
SERIOUS
Medicines with composition S-Amlodipine: S-Amcard, Esam, Big Dvr
Limus with Ketoconazole
SERIOUS
Medicines with composition Ketoconazole: Hyporal
Limus with Nimodipine
SERIOUS
Medicines with composition Nimodipine: Nimpod, Nimocer, Vasotop
Limus with Nifedipine
SERIOUS
Medicines with composition Nifedipine: Calnif, Depicor, Calbloc, Calcigard, Nicardia, Nepin, Nefidipine, Cardipin, Depin, Nifelat, Nifedine, Nifidip
Limus with Enalapril
SERIOUS
Medicines with composition Enalapril: Envas, Minipril, EL, Enapril, Hytrol, Bql, Normace, Canvas, Tenam, Nuril, Enace, Enam, Encardil, Myoace, Vasopril
Limus with Itraconazole
SERIOUS
Medicines with composition Itraconazole: Itrasig, Itracan, Candiforce, Canditral, Onitraz, Iycotizol, Itrasys, Syntran, Nixitral, I-Tyza, Afderm, Itraderm
Limus with Ritonavir
SERIOUS
Medicines with composition Ritonavir: Viriton, Ritomune, Ritomax
Limus with Phenytoin
SERIOUS
Medicines with composition Phenytoin: Episol, Neptoin, C-Toin, Eptoin
Limus with Lercanidipine
SERIOUS
Medicines with composition Lercanidipine: Lotensyl
Limus with Danazol
SERIOUS
Medicines with composition Danazol: Gonablok, Ladogal, Endometryl
Limus with Posaconazole
SERIOUS
Medicines with composition Posaconazole: Noxafil
Limus with Fosphenytoin
SERIOUS
Medicines with composition Fosphenytoin: Fosphen, Fosentin
Limus with Perindopril
SERIOUS
Medicines with composition Perindopril: Perihart

Substitutes for Limus Tablet

Siromus 1mg Tablet
Zydus Cadila
₹173.64/Tablet
27% costlier
Rocas 1mg Tablet
Emcure Pharmaceuticals Ltd
₹128.1/Tablet
save 6%
₹173.03/Capsule
27% costlier
Emtor 1mg Tablet
Emcure Pharmaceuticals Ltd
₹128.1/Tablet
save 6%
Sirova 1mg Tablet
Intas Pharmaceuticals Ltd
₹150.25/Tablet
10% costlier
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