Product introduction
Lez 2.5 Tablet helps treat breast cancer in post-menopausal women. It may be used alone or with other treatments, such as surgery or radiation. It can also be used in patients with advanced breast cancer to stop the tumor from spreading to other parts of the body.
Lez 2.5 Tablet can be taken with or without food. Take it in the dose and duration prescribed by the doctor to get the most benefit. The dose and frequency depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed.
The most common side effects of this medicine include hot flashes. If any other side effects bother you or appear serious, let your doctor know. Your doctor may suggest ways to prevent or reduce these.
Before taking this medicine, tell your doctor if you have ever had liver or kidney disease, or have a history of osteoporosis (thinning or wasting of bones). Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may perform some blood tests to check for vitamin D levels or bone density before and during treatment.
Uses of Lez Tablet
Benefits of Lez Tablet
In Breast cancer
Lez 2.5 Tablet is used in the treatment of hormone-sensitive breast cancer, especially in postmenopausal women. It helps lower the risk of cancer returning and supports long-term recovery after initial treatment.
How to use Lez Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lez 2.5 Tablet may be taken with or without food.
How Lez Tablet works
Lez 2.5 Tablet is an aromatase inhibitor. It works by decreasing the amount of estrogen (natural female hormone) produced in the body. This decrease in estrogen can slow down or stop the growth of some breast cancers that need estrogen to grow.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Lez 2.5 Tablet. Please consult your doctor.
Pregnancy
UNSAFE
Lez 2.5 Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
UNSAFE
Lez 2.5 Tablet is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Lez 2.5 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Lez 2.5 Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
However, there is limited information on the use of this medicine in patients with end stage kidney disease. Please consult with your doctor.
Liver
CAUTION
Lez 2.5 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Lez Tablet?
If you miss a dose of Lez 2.5 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Lez 2.5 Tablet
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Quick tips
- You have been prescribed Lez 2.5 Tablet for the treatment of breast cancer.
- It can be taken with or without food.
- Do not drive or do anything requiring concentration until you know how Lez 2.5 Tablet affects you.
- It may cause increased sweating and hot flushes. Try to keep cool by wearing light and airy clothes.
- Your doctor may monitor your cholesterol level and bone mineral density (BMD) regularly as Lez 2.5 Tablet can alter their levels.
- Do not take Lez 2.5 Tablet if you are pregnant or breastfeeding
Fact Box
Chemical Class
Diphenylmethanes
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Aromatase Inhibitors
Interaction with drugs
Taking Lez with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Letrozole with Allylestrenol if you have or had breast cancer. If essential, consult your doctor.
Allylestrenol may reduce the efficacy of Letrozole.
Do not consume Letrozole with Dehydroepiandrosterone (Micronized) if you have or had breast cancer. If essential, consult your doctor.
Dehydroepiandrosterone (Micronized) may redu
Do not consume Letrozole with Desogestrel if you have or had breast cancer. If essential, consult your doctor.
Desogestrel may reduce the efficacy of Letrozole.
Do not consume Tamoxifen with Letrozole. If concurrent use is essential, please consult your doctor. Tamoxifen may reduce blood levels of Letrozole.
Patient concerns
FAQs
Why have I been prescribed Lez 2.5 Tablet?
Lez 2.5 Tablet is an aromatase inhibitor. It is generally prescribed to treat breast cancer in women who no longer have periods, either due to menopause or after surgery or chemotherapy.
How does Lez 2.5 Tablet work?
Lez 2.5 Tablet is also known as an anti-estrogen drug. It is called so because it acts by reducing the production of estrogen in your body by blocking the enzyme aromatase, which is responsible for the production of estrogen. Estrogen stimulates the production of certain types of breast cancer in your body. These cancers are called "estrogen-dependent cancers". Reducing the production of estrogen may prevent cancer from growing.
For how long should I take Lez 2.5 Tablet?
If the breast tumor is in the advanced stage or has spread to other parts of the body, it is recommended that you continue taking Lez 2.5 Tablet till the tumor shows progression. In cases where Lez 2.5 Tablet is given after tamoxifen (another anti-estrogen used for breast cancer) or surgery, it should be given for 5 years or until the tumor comes back, whichever is first. It can also be given as a sequential treatment; 2 years of Lez 2.5 Tablet followed by 3 years of tamoxifen.
If I am taking irbesartan to control my blood pressure, can I take Lez 2.5 Tablet?
Yes, you can take irbesartan and Lez 2.5 Tablet together. However, be careful and keep a regular check on your blood pressure since Lez 2.5 Tablet may increase your blood pressure. Consult your doctor in case you have problems controlling your blood pressure.
Does Lez 2.5 Tablet affect vision?
Although it is very uncommon, Lez 2.5 Tablet may cause a cataract. So, if you experience blurred vision or eye irritation, consult your doctor immediately.
My friend who is taking Lez 2.5 Tablet often sweats a lot. Is it because of Lez 2.5 Tablet?
This could be a sign of hot flushes which is a very common side effect of Lez 2.5 Tablet. It happens due to decreased estrogen levels. The frequency of hot flushes reduces once your body adjusts to Lez 2.5 Tablet. However, in some people, the flushes and sweats may continue during the treatment and stop a few months after the treatment finishes. You can consult your doctor who will provide you a remedy if it is very bothersome.
What are the serious side effects of Lez 2.5 Tablet?
The serious side effects do not occur in everyone and very few people experience them. The serious side effects of Lez 2.5 Tablet include stroke, angina, heart attack, blood clotting, cataract, osteoporosis, and severe skin reactions.
Does Lez 2.5 Tablet cause bone loss?
Lez 2.5 Tablet may cause thinning or wasting of your bones (osteoporosis), which is due to the decrease in estrogen levels in your body. Your doctor may decide to measure your bone density (a way of monitoring for osteoporosis) before, during and after treatment.
Can I take Lez 2.5 Tablet for induction of ovulation in anovulatory infertility?
As per the Ministry of Health and Family Welfare, Lez 2.5 Tablet is restricted for use in induction of ovulation in anovulatory infertility.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Moy B, Lee RJ, Smith M. Natural Products in Cancer Chemotherapy: Hormones and Related Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1762.
- Masters SB. Hypothalmic & Pituitary Hormones. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 718.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 786-87.
- Letrozole. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 1997 [revised Jan. 2014]. [Accessed 03 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 04 Apr. 2019] (online) Available from:
- National Health Service. Letrozole. [Last Reviewed: 21 Jul 2020]. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole [Package Insert]. Mumbai, India: HOPE Lifecare. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole [Prescribing Information]. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2020. [Accessed 08 Jul. 2023]. (online) Available from:
- Letrozole. Mahaboob Nagar, Telangana: Hetero Labs Ltd.; [Accessed 04 Jan. 2026]. (online). Available from:
- Letrozole. Secundarabad, Telangana: Steris Healthcare Pvt. Ltd.; [Accessed 04 Jan. 2026]. (online). Available from:
Marketer details
Name: West-Coast Pharmaceutical Works Ltd
Address: Gota, Ahmedabad 382481, Gujarat, India
Country of origin: India
Expires on or after: May, 2026
A licensed vendor partner from your nearest location will deliver Lez 2.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: May, 2026
A licensed vendor partner from your nearest location will deliver Lez 2.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹106.88 8% OFF
₹98.4
Inclusive of all taxes
10.0 tablets in 1 strip
The price displayed is the MRP (inclusive of applicable taxes). Any additional fee (such as shipping fee, handling and/or platform fee etc.) will be clearly disclosed before you complete your purchase.
Get by Monday, 9 February
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