
Lagesic Injection
Written By Dr. Swati Mishra, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 02 Feb 2026 | 07:44 PM (IST)
Lagesic Injection is a pain-relieving medicine. It is used to manage persistent, moderate to severe chronic pain that requires continuous, around-the-clock treatment.
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General Information
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Product introduction
Lagesic Injection is generally administered by a healthcare professional. You should not self-administer this medicine at home. The dose and duration will depend on what you are taking it for and how well it helps your symptoms.
The most common side effects of this medicine include nausea, constipation, dry mouth, sleepiness, dizziness, and vomiting. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
The most common side effects of this medicine include nausea, constipation, dry mouth, sleepiness, dizziness, and vomiting. If any of these side effects persist or get worse, you should let your doctor know. Your doctor may be able to suggest ways of preventing or reducing the symptoms.
Before using it, you should let your doctor know if you have problems with your heart, liver, or kidneys. Let your doctor also know about all the other medicines you are taking because they may affect, or be affected by, this medicine.
If you are pregnant or breastfeeding, it is important to ask the advice of your doctor before taking this medicine. Your doctor may also regularly monitor your kidney function, liver function, and levels of blood components if you are taking this medicine for long-term treatment.
Uses of Lagesic Injection
- Moderate to severe pain
Benefits of Lagesic Injection
Moderate to severe pain
Lagesic Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Lagesic Injection helps to relieve moderate to severe pain in conditions that affect joints and muscles. It works by blocking chemical messengers in the brain that tell us we have pain. It can help relieve pain in conditions like rheumatoid arthritis and osteoarthritis.
It is given as an injection by a doctor or nurse and should not be self-administered. The dose and duration will be decided by the doctor depending on the condition you are being treated for. This will help you to go about your daily activities more easily and have a better, more active, quality of life.
Side effects of Lagesic Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Lagesic
- Nausea
- Constipation
- Sleepiness
- Dizziness
- Vomiting
How to use Lagesic Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Lagesic Injection works
Lagesic Injection is an opioid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception.
Quick tips
- Use only for severe acute pain for not more than 5 days.
- Prolonged use may result in physical and psychological dependence even at recommended dosages.
- Avoid driving or using machinery if you feel dizzy after taking Lagesic Injection.
- It is better to take with food to avoid an upset stomach.
- Your doctor may adjust your dose if you have liver or kidney disease.
Safety advice

Alcohol
UNSAFE
Do not drink alcohol while you are taking this medicine. Lagesic Injection may cause excessive drowsiness when taken with alcohol.

Pregnancy
CONSULT YOUR DOCTOR
Lagesic Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding
UNSAFE
Lagesic Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.
Consult a doctor immediately if the baby shows signs of increased sleepiness (more than usual), difficulty breastfeeding, breathing problems, or limpness.

Driving
UNSAFE
Lagesic Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Lagesic Injection may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.
Lagesic Injection may cause side effects such as drowsiness and blurred vision. If this happens, do not drive.

Kidney
CAUTION
Lagesic Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver
CAUTION
Lagesic Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Interaction with drugs
Taking Lagesic with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening
Selegiline (Oral Route)
Do not consume Selegiline with Tramadol. If essential, watch out for symptoms such as fever, tremors, diarrhea or agitation. Please consult your doctor.
Life-threatening
Naltrexone (Oral Route)
Do not consume Naltrexone with Tramadol; watch out for symptoms such as breathlessness, increased heart rate, or headache. Naltrexone may reduce efficacy of Tramadol.
Life-threatening
Tranylcypromine (Oral Route)
Do not consume Tranylcypromine with Tramadol. If Tranylcypromine is essential, ensure a gap of At least 2 weeks between taking Tranylcypromine and Tramadol. Please consult your doctor.
Severe
Alprazolam (Oral Route)
If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Severe
Alprazolam (Injection Route)
If concurrent use is essential, watch out for symptoms of Alprazolam side effects such as drowsiness, excessive sedation, tiredness, dizziness or slurred speech and consult your doctor if you experience them. They may adjust the dose of Alprazolam as per the observations. It is advised to avoid driving or undertaking other tasks requiring skill and alertness.
Frequently asked questions
Lagesic Injection may cause drowsiness and dizziness, especially in the beginning of the treatment. Do not drive or work with tools or machinery if your alertness is affected. It is not advisable to drink alcohol during treatment with this medicine as it might increase sleepiness.
Fact Box
Chemical Class
Phenylpropylamine derivative
Habit Forming
Yes
Therapeutic Class
PAIN ANALGESICS
Action Class
Opioids
References
- Schumacher MA, Basbaum AI, Way WL. Opioids Analgesics & Antagonists. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 547.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1384-86.
- ScienceDirect. Tramadol. [Accessed 02 Apr. 2019] (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 02 Apr. 2019] (online) Available from:

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