Kombiglyze XR 5mg/1000mg Tablet


Overview

Uses of Kombiglyze Tablet ER
Kombiglyze XR 5mg/1000mg Tablet is used in the treatment of type 2 diabetes.
Kombiglyze Tablet ER side effects
Common
  • Diarrhoea
  • Nausea
  • Vomiting
  • Stomach upset
  • Headache
  • Nasal congestion
  • Sore throat
  • Respiratory tract infection
  • Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
How to use Kombiglyze Tablet ER
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Kombiglyze XR 5mg/1000mg Tablet is to be taken with food.
Kombiglyze XR 5mg/1000mg Tablet may cause stomach upset if taken on empty stomach.
How Kombiglyze Tablet ER works
Kombiglyze XR 5mg/1000mg Tablet is a combination of two antidiabetic medicines: Saxagliptin and Metformin. Saxagliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
Kombiglyze Tablet ER related warnings
Alcohol
CAUTION
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
Pregnancy
PROBABLY SAFE
Kombiglyze XR 5mg/1000mg Tablet is probably safe to use during pregnancy.
Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor.
Lactation
Kombiglyze XR 5mg/1000mg Tablet is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
Driving
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Kidney
CAUTION
Kombiglyze XR 5mg/1000mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Kombiglyze XR 5mg/1000mg Tablet may be needed. Please consult your doctor.
Use of Kombiglyze XR 5mg/1000mg Tablet is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Liver
CAUTION
Kombiglyze XR 5mg/1000mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Kombiglyze XR 5mg/1000mg Tablet may be needed. Please consult your doctor.
Kombiglyze XR 5mg/1000mg Tablet is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Kombiglyze XR 5mg/1000mg Tablet
₹51/Tablet ER
Riax-M XR 5mg/1000mg Tablet
Dr Reddy's Laboratories Ltd
₹51/Tablet ER
same price

Expert Advice

  • You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
  • Take it in addition to regular exercise and healthy diet to lower levels of blood sugar.
  • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
  • Take it with food to lower your chance of having an upset stomach.
  • Monitor your blood sugar level regularly while you are taking this medicine. 
  • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain as Kombiglyze XR 5mg/1000mg Tablet may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.

Patient Concerns

Questions Related to Kombiglyze

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I am a diabetic patient since last 12 year and using insulin 30+25 everyday. Moreover two tablet ( 1 kombiglyze 1000 and glycomise 1000) using everyday. Now the problem is I am facing too much sexual weakness. What can I do to get from this problem. Please prescribe if any medicines is available for this. With regards PATIENT
Dr. Anirban Poddar
Diabetes Specialist
Although erectile dysfunction is common in diabetics,but at the age of 56 mild dysfunction is common as it is the time when the sex drive gradually wears off in males.So its normal dont worry
High cholesterol and lipid. Also type 2 diabetes under control. Vegetarian. Pls advise on dite
Dr. Waseem Mirza
Sexologist
Per day calorie intake should be between 1,500-1,800 calories with a proportion of 60:20:20 between carbohydrates, fats and proteins, respectively, take Healthy fats from raw nuts, olive oil, fish oils, flax seeds etc, fresh Fruits and vegetables,whole grains, legumes and other high-fibre diet, avoid refined carbohydrate diet,if u eat non veg u can take fish, poultry egg white, pulses whereas avoid red meat, avoid saturated fats like ghee, butter, avoid sweet foods, take small but frequent meals, supplements containing omega 3 fatty acids like Multivite fm omega capsule Quit smoking, avoid too much alcohol intake, find ways to reduce stress like meditation, yoga, etc. Moderate exercise daily like a brisk walk for 1 km. hope it helps
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User Feedback


Information last updated by Dr. Varun Gupta, MD Pharmacology on 10th Sep 2018.
The medicine details are for information purpose only. Consult a doctor before taking any medicine.
Manufacturer/Marketer Address
Corporate & Registered Office, Block N1, 12th Floor, Manyata Embassy Business Park, Rachenahalli, Outer Ring Road, 560045, Bangalore
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MRP
357
7 tablet er in 1 strip
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Best Price ₹285.6
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