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    Saxagliptin + Metformin

    Information about Saxagliptin + Metformin

    Saxagliptin + metformin uses

    Saxagliptin+Metformin is used in the treatment of type 2 diabetes mellitus.

    How saxagliptin + metformin works

    This is a combination of two antidiabetic medicines: Saxagliptin and Metformin. Saxagliptin is a dipeptidyl peptidase-4 inhibitor which works by increasing the release of insulin from pancreas and decreasing the hormones that raise blood sugar levels. This reduces both fasting and postmeal sugar levels. Metformin is an anti-diabetic medication (biguanide). It works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.

    Common side effects of saxagliptin + metformin

    Diarrhea, Nausea, Vomiting, Stomach upset, Headache, Nasal congestion, Sore throat, Respiratory tract infection, Hypoglycaemia (low blood sugar level) in combination with insulin or sulphonylurea
    Content Details
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    Written By
    Dr. Anuj Saini
    MMST, MBBS
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    Reviewed By
    Dr. Varun Gupta
    MD (Pharmacology), MBBS
    Last updated on:
    11 Nov 2019 | 01:59 PM (IST)
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    Available Medicine for Saxagliptin + Metformin

    • ₹357
      AstraZeneca
      2 variant(s)
    • ₹329 to ₹357
      Dr Reddy's Laboratories Ltd
      2 variant(s)

    Expert advice for Saxagliptin + Metformin

    • Take it with food to lower your chance of having an upset stomach.
    • Chances of weight gain and low blood sugar are lesser as compared to other diabetes medicines. 
    • Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
    • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, and stomach pain as Saxagliptin + Metformin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.


    Content on this page was last updated on 11 November, 2019, by Dr. Varun Gupta (MD Pharmacology)