


Klox 500mg Injection
Cloxacillin (500mg)
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Klox 500mg Injection is an antibiotic used to treat a variety of bacterial infections. It is effective in infections of the throat, ear, nasal sinuses, respiratory tract, skin and soft tissue, bones and joints, and blood.
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Aug 2026 | 01:04 AM (IST)
Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 10 Aug 2026 | 01:04 AM (IST)
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General Information
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Product introduction
Klox 500mg Injection is a penicillin-type of antibiotic, which mainly fights and stops the growth of the gram-positive type of bacteria. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. This medicine should be used regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening. The total duration of treatment and precise dosage will be decided by your doctor, depending on the type of infection that you have and how well you respond to the medication.
Before taking this medicine, inform your doctor if you are allergic to penicillin or penicillin-type of medicine. Rash, allergic reactions, and local pain, swelling, redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.
Before taking this medicine, inform your doctor if you are allergic to penicillin or penicillin-type of medicine. Rash, allergic reactions, and local pain, swelling, redness at the site of injection may be seen as side effects in some patients. These are temporary and usually resolve quickly. Consult your doctor if any of these side effects persist or if your condition worsens. This medicine is generally regarded as safe to use during pregnancy if used under a doctor’s supervision.
Uses of Klox Injection
Benefits of Klox Injection
Bacterial infections
Klox 500mg Injection is an antibiotic medicine that works by killing the infection causing bacteria in your body. It is effective for bacterial infections of the throat, ears, urinary tract, skin, and soft tissues. Klox 500mg Injection is given by a doctor or a nurse and should not be self-administered. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better. Stopping it early may make the infection come back and harder to treat.
Klox 500mg Injection is an antibiotic medicine that works by killing the infection causing bacteria in your body. It is effective for bacterial infections of the throat, ears, urinary tract, skin, and soft tissues. Klox 500mg Injection is given by a doctor or a nurse and should not be self-administered. This medicine usually makes you feel better within a few days, but you should continue taking it as prescribed even when you feel better. Stopping it early may make the infection come back and harder to treat.
Side effects of Klox Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Klox
- Hypersensitivity
How to use Klox Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Klox Injection works
Klox 500mg Injection is an antibiotic. It kills bacteria by preventing them from forming their own protective covering (cell wall) which is needed for them to survive.
Quick tips
- You have been prescribed Klox 500mg Injection for the treatment of bacterial infections.
- It is given by an injection into a vein or muscle, or via a drip into a vein.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
- You have been prescribed Klox 500mg Injection for the treatment of bacterial infections.
- It is given by an injection into a vein or muscle, or via a drip into a vein.
- Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat.
- Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it doesn't stop or if you find blood in your stools.
- Inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.
Safety advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Klox 500mg Injection. Please consult your doctor.

Pregnancy
CONSULT YOUR DOCTOR
The safety of Klox 500mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding
SAFE IF PRESCRIBED
Klox 500mg Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Driving
SAFE
Klox 500mg Injection does not usually affect your ability to drive.

Kidney
CAUTION
Klox 500mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised while taking this medicine.
Regular monitoring of kidney function tests is advised while taking this medicine.

Liver
CONSULT YOUR DOCTOR
There is limited data available on the use of Klox 500mg Injection in patients with liver disease.
Regular monitoring of liver function tests is advised while taking this medicine.
Regular monitoring of liver function tests is advised while taking this medicine.

Interaction with drugs
Taking Klox with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe
Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)
Cloxacillin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Cloxacillin may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Severe
Cholera Vaccine (Inactivated) (Oral Route)
Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Cloxacillin. Please consult your doctor. Cloxacillin may reduce the efficacy of Cholera Vaccine (Inactivated).
Moderate
Kanamycin (Injection Route)
Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.
Moderate
Streptomycin (Injection Route)
Let your doctor know if you have a history of kidney disease. Your doctor may monitor your kidney function regularly.
Frequently asked questions
Klox 500mg Injection is used to treat a wide variety of bacterial infections. It is a type of penicillin antibiotic that works by stopping the growth of bacteria.
Usually, Klox 500mg Injection starts working soon after taking it. However, it may take around 2-3 days to make you feel better while taking Klox 500mg Injection.
Klox 500mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Klox 500mg Injection too early, the symptoms may return or worsen.
Klox 500mg Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Klox 500mg Injection.
Although it is rare but yes, Klox 500mg Injection can cause allergic reaction and is harmful in patients with known allergy to penicillins. Get emergency medical help if you have any of the signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Taking Klox 500mg Injection with food will only make it less effective. Moreover, the absorption of this medicine is the most when taken on an empty stomach. Taking it with food reduces its absorption.
Klox 500mg Injection is safe if used in the dose and duration advised by your doctor. Take it exactly as directed and do not skip any dose. Follow your doctor's instructions carefully and let your doctor know if any of the side effects bother you.
Fact Box
Chemical Class
Dipeptides
Habit Forming
No
Therapeutic Class
ANTI INFECTIVES
Action Class
Penicillinase-Resistant Penicillins
Related lab tests
References
- Petri WA Jr. Penicillins, Cephalosporins, and Other β -Lactam Antibiotics. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1486-87.
- ScienceDirect. [Accessed 29 Mar. 2019 (online) Available from:
- Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
Marketer details
Name: Hetero Drugs Ltd
Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA
Address: 7-2-A2, Hetero Corporate, Industrial Estates, Sanath Nagar, Hyderabad – 500 018. Telangana, INDIA
Vendor Details
Country of origin: India
Lab tests offered by us
- CBC (Complete Blood Count)
- FBS (Fasting Blood Sugar)
- Thyroid Profile Total (T3, T4 & TSH)
- HbA1c (Glycosylated Hemoglobin)
- PPBS (Postprandial Blood Sugar)
- Lipid Profile
- Vitamin D (25-Hydroxy)
- Urine R/M (Urine Routine & Microscopy)
- Coronavirus Covid -19 test- RT PCR
- LFT (Liver Function Test)
- KFT (Kidney Function Test)
- TSH (Thyroid Stimulating Hormone) Ultrasensitive
- ESR (Erythrocyte Sedimentation Rate)
- Uric Acid, Serum
- Vitamin B12
- CRP (C-Reactive Protein), Quantitative
- Urine C/S (Urine Culture and Sensitivity)
- Serum Electrolytes
- Serum Calcium
- Serum Creatinine
- Diabetes Screening (HbA1C & Fasting Sugar)
- KFT with Electrolytes (Kidney Function Test with Electrolytes)
- Cholesterol - Total
- Hb (Hemoglobin)
- Complete Hemogram (CBC & ESR)
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