Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isonij 300mg Tablet is to be taken empty stomach. Avoid Isonij 300mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.
Isonij 300mg Tablet may cause symptoms such as flushing, increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
WEIGH RISKS VS BENEFITS
Isonij 300mg Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Isonij 300mg Tablet is safe to use during lactation.
Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well. Isonij 300mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Isonij 300mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isonij 300mg Tablet is recommended. However, talk to your doctor if you have any underlying kidney disease.
Isonij 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Isonij 300mg Tablet may be needed. Please consult your doctor. Use of Isonij 300mg Tablet is not recommended in patients with severe liver disease.
If you miss a dose of Isonij 300mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Isonij is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Isonij is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isonij. You may experience few of these side effects while on multi drug (including Isonij) treatment for tuberculosis
You may experience unusual tiredness, constipation or acne while on treatment with Isonij. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Isonij has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.