Isoniazid 300mg Tablet

Cadila Pharmaceuticals Ltd

Composition for Isoniazid 300mg Tablet

iconPrescription Required

Primarily used for

10 tablets in 1 strip

Medicine Overview of Isoniazid Tablet


Uses of Isoniazid Tablet

Isoniazid 300mg Tablet is used in the treatment of tuberculosis
It is also used to treat inactive (latent) TB .

Side effects of Isoniazid Tablet


Peripheral neuropathy (tingling and numbness of feet and hand), Increased liver enzymes, Hepatitis (viral infection of liver), Jaundice.


How to use Isoniazid Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isoniazid 300mg Tablet is to be taken empty stomach.
Avoid Isoniazid 300mg Tablet with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Isoniazid Tablet works

Isoniazid 300mg Tablet is an antibiotic. It works by killing the bacteria that causes tuberculosis.

In Depth Information on Isoniazid Tablet

Expert advice for Isoniazid Tablet

  • Take it on an empty stomach (if it upsets your stomach, take it with food).
  • Take it as and when prescribed (in case you skip a dose, do not take two doses at one time).
  • In order to kill the TB bacteria and cure the disease completely, you will have to take this medicine for 6 to 12 months (your doctor will the precise duration for which you will take the medicine).
  • You need to take vitamin B6 (Pyridoxine) along with Isoniazid. Vitamin B6 (Pyridoxine) will prevent possible numbness and tingling fingers and toes that may be caused by Isoniazid.
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Special precautions for Isoniazid 300mg Tablet
Isoniazid 300mg Tablet may cause symptoms such as flushing,
increased heartbeat, nausea, thirst, chest pain and low blood pressure with alcohol (Disulfiram reactions).
Isoniazid 300mg Tablet may be unsafe to use during pregnancy.

Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Isoniazid 300mg Tablet is safe to use during lactation. Hum
an studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby.
Do not drive unless you are feeling well.

Isoniazid 300mg Tablet can cause fits, mental health problems and optic neuritis (inflammation of the optic nerve that may cause loss of vision.) This may affect your driving ability.
Isoniazid 300mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Isoniazid 300mg Tablet is recommended.

However, talk to your doctor if you have any underlying kidney disease.
Isoniazid 300mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Isoniazid 300mg Tablet may be needed. Please consult your doctor.

Use of Isoniazid 300mg Tablet is not recommended in patients with severe liver disease.
Severely interacts with other drugs like
Mezolam 7.5mg Injection, Zee 2mg Tablet, Clonotril 2mg Tablet, Zep 10mg Tablet

Missed Dosageuses

If you miss a dose of Isoniazid, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
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Patient Concerns

Frequently asked questions for Isoniazid 300mg Tablet

Frequently asked questions for Isoniazid

Isoniazid is an antibiotic used in the prevention and treatment of tuberculosis or TB (a serious infection caused by bacteria that affects the lungs and in certain cases other parts of the body)
Isoniazid is a primary antibiotic used for treatment of tuberculosis. Do not confuse it with chemotherapy or chemo drugs used for the treatment of cancer
Isoniazid is a bacteriostatic antibiotic. It stops or suppresses growth of tuberculosis causing bacteria by interfering with the formation of protective outer covering (cell wall) which is essential for their growth
Yes. Isoniazid is safe if used at prescribed doses for the prescribed duration as advised by your doctor
Isoniazid has very weak inhibitory activity on enzymes monoamine oxidases (MAO); however it is not used as a monoamine oxidase inhibitor (MAOI)
No. The chemical structure and mechanism of action of Isoniazid is different from sulfa drugs
Isoniazid is an inhibitor (decreases activity) of an important liver enzyme system that is responsible for the final processing and elimination of several drugs from the body
Q. Can I take isoniazid with ibuprofen/Benadryl/Nyquil/Aleve/Mucinex/amoxicillin?
There no known serious drug interactions of isoniazid with ibuprofen, paracetamol (trade name: Tylenol), naproxen (trade name: Aleve), amoxicillin or any active drug present in Nyquil or Mucinex. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Changes in body weight (gain/loss), hair loss, diarrhea or changes in menstruation are not among the known side effects of Isoniazid. You may experience few of these side effects while on multi drug (including Isoniazid) treatment for tuberculosis
You may experience unusual tiredness, constipation or acne while on treatment with Isoniazid. Please inform your doctor about all the medication you are currently taking to avoid interactions that may reduce effectiveness of any treatment or aggravate side effects
Isoniazid has no known interaction with commonly used oral contraceptives (birth control pills). However, multidrug treatment for tuberculosis contains active drug rifampin that decreases the effectiveness of oral contraceptives and hampers birth control.

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