Delivering to Gurgaon
Hi, there!
Login / Sign Up
Buy medicines
Buy health products
Book lab tests
Consult a doctor
1mg Care Plan
Cancer Care
Ayurveda
Partnerships
New
Hindi articles
Offers
All diseases
New
All medicines
Medicines by therapeutic class
Contact us
Need help?
Privacy policy
Return policy
Terms and conditions
Editorial policy
Get more features! Download the app now
Medicine Reminders
Monthly/weekly subscriptions
Health records and analysis
24*7 Emergency services
Download app on the App StoreDownload app on the Google play store
Choose city
Sign in to your account
or
By signing in you agree to our
Terms & conditions
 and 
Privacy policy
sold out tag

Isolazine Tablet

Written By Dr. Sakshi Jain, MS, BDS
Reviewed By Dr. Mekhala Chandra, MD, MBBS
Last updated on 02 Mar 2026 | 12:39 PM (IST)
Isolazine Tablet is used in the treatment of heart failure. It is a combination of two medicines that effectively control symptoms of heart failure.
Genuine
Authenticity Assured
Prescription
required
₹74.5 MRP ₹81.569% off 
We do not facilitate sale of this product at present
 
 
0
footer-icon
sku_image
Available in pack-size of 15 tablets
15 tablets pack-size available
Isolazine Tablet
₹217₹237.7
Available in pack size of 15 tablets
Sold out
Isolazine Tablet
Isolazine Tablet
strip of 10 tablets
₹74.5
₹81.56
tag icon
Different pack-size
Isolazine Tablet
Isolazine Tablet
strip of 15 tablets
Isosorbide Dinitrate (20mg) + Hydralazine (37.5mg)
by Lupin Ltd
Get by 2pm
₹217
₹14.47 per tablet

Save more with additional offers

offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*
chevron icon
offer icon
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20
chevron icon
offer icon
Earn cashback up to Rs. 100 with Amazon Pay Later
Earn cashback up to Rs. 100 with Amazon Pay Later
chevron icon
offer icon
Get cashback up to ₹500
Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.
chevron icon
offer icon
Get upto Rs.150 Cashback
Get upto Rs.150 Cashback
chevron icon

General Information

Contains

Isosorbide Dinitrate (20mg)+ Hydralazine (37.5mg)

Marketer

Lupin Ltd

Storage

Store below 30°C
The content is shown in English
Isolazine Tablet image
Isolazine Tablet image
Isolazine Tablet image
Isolazine Tablet image
Isolazine Tablet image
Isolazine Tablet image

Product introduction

Isolazine Tablet should be taken with food regularly at a fixed time each day. You should take it regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Taking it at the same time every day will help you remember to take it. The dose and duration of treatment will depend on what you are being treated for. Do not stop taking it until you have finished the complete course, even when you feel better. Lifestyle changes like a low-fat diet, exercise, and not smoking may help this medicine to work better.

It is generally safe and suitable for most people but has some potential side effects. The most common side effects of this medicine include nausea, vomiting, diarrhea, low blood pressure, and loss of appetite. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them. It makes you feel dizzy as of orthostatic hypotension (sudden lowering of blood pressure on standing). Hence, rise slowly while from a sitting position or avoid driving. You may be asked for regular monitoring of blood pressure while on the treatment.

Before taking this medicine, tell your doctor if you have liver or kidney disease. You must tell your doctor if you are pregnant, planning pregnancy, or breastfeeding. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine.

Uses of Isolazine Tablet

Benefits of Isolazine Tablet

Treatment of Heart Failure
Heart failure means your heart is weak and cannot pump enough blood to your lungs and the rest of your body. The most common symptoms are breathlessness, tiredness, and swelling in your legs, ankles, abdomen and other parts of your body. Isolazine Tablet makes it easier for your heart to pump blood around your body and is therefore an effective treatment for heart failure.
This medicine will help relieve your symptoms, making you feel better and more energetic. You should make appropriate lifestyle changes, such as eating healthy and keeping active, to help this medicine be effective. Take it regularly and keep taking it even if you feel better.

Side effects of Isolazine Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Isolazine
  • Nausea
  • Headache
  • Dizziness
  • Weakness
  • Ventricular tachycardia
  • Paralysis of ileus
  • Hypotension (low blood pressure)
  • Visual impairment

How to use Isolazine Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isolazine Tablet should be taken with or after food.

How Isolazine Tablet works

Isolazine Tablet is a combination of two medicines:

All substitutes for Isolazine Tablet

For information purposes only. Consult a doctor before taking any medicine.

APREsol Plus Tablet

by Ordain Health Care Global Pvt Ltd
₹10.5/tablet
41% costlier
<h3 class=bodySemiBold>APREsol Plus Tablet</h3>

Nitrohart Tablet

by Mankind Pharma Ltd
₹8.31/tablet
12% costlier
<h3 class=bodySemiBold>Nitrohart Tablet</h3>

Isorus Tablet

by Ajanta Pharma Limited
₹12.53/tablet
68% costlier
<h3 class=bodySemiBold>Isorus Tablet</h3>

Sorba HF 20mg/37.5mg Tablet

by Daxia Healthcare
₹9.1/tablet
22% costlier
<h3 class=bodySemiBold>Sorba HF 20mg/37.5mg Tablet</h3>

Isonit Plus Tablet

by Tas Med India Pvt Ltd
₹10.3/tablet
38% costlier
<h3 class=bodySemiBold>Isonit Plus Tablet</h3>

Quick tips

  • Isolazine Tablet is a combination of two medicines that helps improve symptoms of heart failure and keeps your heart healthier.
  • This medicine may temporarily cause headaches, especially when starting treatment. Inform your doctor if it does not go away.
  • Isolazine Tablet may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you.
  • To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It is best to avoid drinking alcohol while taking Isolazine Tablet as it may make the side effects worse.
  • Do not take it in combination with  medicines that treat erectile dysfunction (eg. sildenafil, tadalafil, vardenafil) or high blood pressure, as that can cause a major drop in blood pressure.
  • Do not stop taking Isolazine Tablet suddenly without talking to your doctor as it can increase the risk of heart attack and stroke.

Safety advice

Alcohol

Alcohol

UNSAFE
Do not drink alcohol while you are taking this medicine. Isolazine Tablet may cause excessive drowsiness when taken with alcohol.
Pregnancy

Pregnancy

UNSAFE
Isolazine Tablet is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

CAUTION
Isolazine Tablet may cause dizziness or weakness due to changes in blood pressure. Do not drive if these symptoms occur.
As Isolazine Tablet may cause headaches or lead to difficulty in concentration and this may affect your ability to drive.
Kidney

Kidney

CAUTION
Isolazine Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of blood pressure is recommended for better dose adjustment.
Liver

Liver

CAUTION
Isolazine Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

No, keep using Isolazine Tablet as advised by your doctor, even if you feel well. Stopping Isolazine Tablet suddenly may lead to serious complications of heart failure.
Keep this medicine in the container or the pack it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.
Isolazine Tablet can frequently cause headaches, especially at the start of the treatment. As the treatment continues, your headache may become less intense and frequent. However, inform your doctor if headache continues.
Yes, the use of Isosorbide Isolazine Tablet can make you feel dizzy. This may often occur when you suddenly rise up from lying or sitting position. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.

Fact Box

Habit Forming

No

Therapeutic Class

CARDIAC

References

  1. Ferdinand KC, Elkayam U, Mancini D, et al. Use of isosorbide dinitrate and hydralazine in African-Americans with heart failure 9 years after the African-American Heart Failure Trial. Am J Cardiol. 2014;114(1):151-9. [Accessed 21 Jan. 2019] (online) Available from:
  2. Mastanamma SK, Saidulu P, Sravanthi A, et al. Stability Indicating Validated RP-HPLC Method for Simultaneous Determination of Hydralazine Hydrochloride and Isosorbide Dinitrate in Bulk and Pharmaceutical Dosage Form. Int J Pharm Sci Rev Res. 2016;40(1):1411-48. [Accessed 21 Jan. 2019] (online) Available from:
  3. Cheng JW. A review of isosorbide dinitrate and hydralazine in the management of heart failure in black patients, with a focus on a new fixed-dose combination. Clin Ther. 2006;28(5):666-78. [Accessed 21 Jan. 2019] (online) Available from:
  4. Isosorbide dinitrate and hydralazine hydrochloride. Seymour, Indiana: Kremers Urban Pharmaceuticals Inc.; 2005 [revised Apr. 2015]. [Accessed 23 Jan. 2019] (online) Available from:
  5. Isosorbide dinitrate and hydralazine hydrochloride [Prescribing Inforamtion]. Seymour, IN: Kremers Urban Pharmaceuticals Inc.; 2015. [Accessed 28th Sept. 2023] (online) Available from:
  6. Central Drugs Standard Control Organization. Isosorbide Dinitrate+Hydralazine. [Accessed 28th Sept. 2023] (online) Available from:
  7. ScienceDirect. Isosorbide Dinitrate. [Accessed 28th Sept. 2023] (online) Available from:
Related products
Products related to Isolazine Tablet
4.5Rating star
Himalaya Abana Tablet | Acts as a Antihyperlipidemic
60 tablets
Get in 60 mins
₹209
₹220
5% off

₹188

order for
₹1200
4.2Rating star
Caleat-KD Plus Tablet
10 tablets
Get by 2pm, Today
₹194
₹204
5% off

₹175

order for
₹1200
4.5Rating star
Himalaya Wellness Pure Herbs Arjuna Cardiac Wellness Tablet
60 tablets
Get in 60 mins
₹312
₹325
4% off

₹281

order for
₹1200
4.5Rating star
Himalaya Wellness Pure Herbs Lasuna Cardiac Wellness Tablet | For Healthy Cholesterol
60 tablets
Get in 60 mins
₹312
₹325
4% off

₹281

order for
₹1200
Avifol Tablet
10 tablets
Get by 2pm, Today
₹84.9
₹88.1
4% off

₹76.4

order for
₹1200
4.8Rating star
Triglize Tablet
30 tablets
Get by 10pm, Today
₹178
₹188
5% off

₹160

order for
₹1200
Desi Jadi Buti Behman Laal
100 gm Pack
Get by Sun, 26 Apr
₹571
₹601
5% off

₹514

order for
₹1200
4.7Rating star
Dr. Reckeweg Aalserum Dilution 6 CH
11 ml Dilution
Get by Tomorrow
₹157
₹160
2% off

₹141

order for
₹1200
MCP Pediatric Stainless Steel Cardiology Stethoscope
1 Unit
Get by Tomorrow
₹963
₹2109
54% off

₹867

order for
₹1200
Bakson's Homoeopathy Fagopyrum Esculentum Dilution 6
30 ml Dilution
Get by Sun, 26 Apr
₹100

₹89.9

order for
₹1200
Related ayurvedic ingredients
Fish Oil
Fish Oil
100% genuine products
100% genuine products
Safe & secure payments
Safe & secure payments
No contact delivery
No contact delivery
Fully sanitized facilities
Fully sanitized facilities

User feedback

Twice A Day
60%
Thrice A Day
40%
Heart failure
67%
Others
14%
Hypertension (high blood pressure)
14%
Angina (heart-related chest pain)
6%
Excellent
45%
Average
40%
Poor
14%
No Side Effect
47%
Loss of appetite
11%
Increased heart rate
11%
Headache
11%
Orthostatic hypotension (sudden lowering of blood pressure on standing)
5%
With food
76%
With or without food
24%
Average
56%
Expensive
27%
Not Expensive
17%
<h3 class=titleMediumExtraBold>Want to know more</h3>

Want to know more

We provide you with authentic, trustworthy and relevant information
<h3 class=titleMediumExtraBold>Have issue with the content</h3>

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lupin Ltd
Address: 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?
close sheet