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Insulin (Nnd) 40IU/ml Injection


Overview

Introduction

Insulin (Nnd) 40IU/ml Injection is a short-acting insulin used to treat type 1 and type 2 diabetes mellitus. It is used together with a healthy diet and regular exercise to control blood sugar levels after meals. This helps to prevent serious complications of diabetes like kidney damage and blindness.

Insulin (Nnd) 40IU/ml Injection is normally prescribed along with a long-acting type of insulin or other diabetes medicines. Your doctor or nurse will teach you the correct way of injecting it under the skin. It should be taken 20-30 minutes before a meal. Do not stop taking it unless your doctor tells you to. It is only a part of the treatment program that should also include a healthy diet, regular exercise, and weight reduction as advised by your doctor. 

Check your blood sugar levels regularly, keep track of your results and share them with your doctor. This is very important to work out the correct dose of the medicine for you. 

The most common side effect of this medicine is low blood sugar levels (hypoglycemia). It may be seen if you do not eat right after a dose of this fast-acting insulin. To prevent this, it is important to always inject only the correct dose of medicine, have regular meals, and monitor your blood sugar levels regularly. Drinking excessive alcohol can also lead to a fall in your blood sugar levels. Other side effects include reactions at the injection site like redness or swelling. Some people gain weight while taking insulin. 

Do not use this medicine when you have low blood sugar levels (hypoglycemia). Tell your doctor if you have ever had kidney, liver or heart problems before starting treatment. Pregnant or breastfeeding women should also consult their doctor as the dose may need to be changed.

Uses of Insulin Injection

Side effects of Insulin Injection

Common
  • Hypoglycemia (low blood glucose level)
  • Injection site allergic reaction

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Injection site allergic reaction
    Try to change the area of injection and the exact site of injection each time. Apply a cold compress to the injection site. These symptoms are usually mild and should only last a few hours. You can ask your doctor to recommend a medicine if it is bothering you.

How to use Insulin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Insulin Injection works

Insulin (Nnd) 40IU/ml Injection is a short-acting insulin, which starts working within 30 minutes after injection. It works similar to the insulin produced by the body. Insulin facilitates reuptake of sugar in muscle and fat cells and also suppresses the production of sugar in the liver.

Safety Advice

Alcohol
UNSAFE
It is unsafe to consume alcohol with Insulin (Nnd) 40IU/ml Injection.
Pregnancy
SAFE IF PRESCRIBED
Insulin (Nnd) 40IU/ml Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Breastfeeding
SAFE IF PRESCRIBED
Insulin (Nnd) 40IU/ml Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
CAUTION
Your ability to drive may be affected if your blood sugar is too low or too high. Do not drive if these symptoms occur.
Kidney
CAUTION
Insulin (Nnd) 40IU/ml Injection should be used with caution in patients with kidney disease. Dose adjustment of Insulin (Nnd) 40IU/ml Injection may be needed. Please consult your doctor.
Regular monitoring of blood glucose levels is recommended for dose adjustment.
Liver
CAUTION
Insulin (Nnd) 40IU/ml Injection should be used with caution in patients with liver disease. Dose adjustment of Insulin (Nnd) 40IU/ml Injection may be needed. Please consult your doctor.
Regular monitoring of glucose levels is recommended for dose adjustment.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Insulin (Nnd) 40IU/ml Injection
₹13.5/ml of Injection
Insucare R 40IU/ml Injection
Sun Pharmaceutical Industries Ltd
₹14.07/ml of Injection
4% costlier
Human Monotard 40IU/ml Injection
Novo Nordisk India Pvt Ltd
₹14.5/ml of Injection
7% costlier
Humarap 40IU/ml Injection
Cadila Pharmaceuticals Ltd
₹14.77/ml of Injection
9% costlier
Huminsulin R 40IU/ml Injection
Eli Lilly and Company India Pvt Ltd
₹15.42/ml of Injection
14% costlier
₹15.47/ml of Injection
15% costlier

Quick Tips

  • Take it 20 to 30 minutes before a meal.
  • Hypoglycemia (low blood sugar level) is a common side-effect. Learn how to identify and manage its symptoms (sweating, rapid heartbeat, weakness, blurry vision, headache) and teach your family as well.
  • Injection below the skin of the abdomen results in faster absorption than other injection sites.
  • Injection sites must be rotated to prevent hard lumps from developing at one site.
  • Opened vials/cartridges are good at room temperature for up to 4 weeks, while unopened vials must be placed in the refrigerator  (2°C–8°C).

Interaction with Drugs

Taking Insulin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Apriace
MODERATE
Brand(s): Capotril, Aceten, Angiopril
MODERATE
Brand(s): Enatol, AB-Pril, Inopril
MODERATE
Brand(s): Fovas
MODERATE

Patient Concerns

arrow
Any latest discoveris for type 1 mellitus Diabetes?
Dr. Sanjay Bhatt
Physician
Diabetes Ireland is delighted to hear of the Harvard success and congratulate Professor Melton and colleagues on figuring out the complex series of steps necessary to turn stem cells into beta cells. Hopefully, they can negotiate the regulations for mass production so that an abundant supply of beta cells is available an new and innovative methods will be developed to cure/treat Type 1 diabetes. Type I diabetes is an autoimmune condition whereby the body kills off its own beta (insulin producing) cells resulting in the need for daily insulin administration through the skin. Replacing beta cells in the first step towards a cure, but the replaced beta cells need to be protected from the body?s autoimmune response. This means protecting them in a coating or taking drugs to prevent the response (possible worse side effects than diabetes).
Suffering from Type 1 diabetes and underweight. Pls let me know to stop using insulin ans to improve health.
Dr. Ashwin Porwal
Internal Medicine
insulin can't be stoppedonly treatment for type 1 diabetes is insulin
arrow
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User Feedback


FAQs

Q. Will I need Insulin for the rest of my life?

If you are a type 1 diabetes patient, then yes, you have to take Insulin for the rest of your life because your body is unable to produce sufficient insulin. Therefore, you would need Insulin as an external source of insulin. However, if you are a type 2 diabetes patient, sometimes your doctor may ask you to stop Insulin if you are able to manage your diabetes with proper exercise, diet and oral medicines.

Q. Can Insulin be used with other diabetes medicine?

Yes, Insulin can be used alone or in combination with other diabetes medicines like long-acting insulin or oral diabetes medicines, along with proper diet and exercise. Follow your doctor’s advice and treatment plan to get the maximum benefit.

Q. How should Insulin be used?

Insulin is injected under the skin (subcutaneously). Your doctor will show you the area of your skin where you should inject it. Try not to inject on the same spot every time. Rotate between the typical injection sites, such as abdomen, buttocks, upper legs or upper arms. Never inject Humalog into a muscle or vein. Move to a new injection site every week or two. Inject in the same area of the body, making sure to move around within that area with each injection, for one or two weeks. You can then move to another area of your body and repeat the process. Use the same area for at least a week to avoid extreme blood sugar variations.

Q. Is Insulin safe to use in pregnancy?

Yes. Insulin is safe to use in pregnancy if prescribed by a doctor. However, please inform your doctor if you are pregnant, planning pregnancy or breastfeeding before using Insulin. You may require dose modifications and your doctor will advise you to monitor your blood sugar levels regularly. You must follow the instructions of your doctor to get maximum benefits.

Q. Is Insulin safe to use in type 2 diabetes?

Yes, insulin is safe to use in type 2 diabetes if used according to your doctor's advice. Keep monitoring your blood sugar levels regularly as advised. Your dosage may need to be adjusted as per your needs. Follow the lifestyle changes as advised by your doctor. Talk to your doctor about the side effects and ways to prevent and manage them.

Q. What are the side effects of Insulin? How to prevent them?

The side effects of Insulin are injection site reactions such as redness, itching, pain and swelling. However, these are temporary and usually resolve on their own. Rarely, it can also cause lipodystrophy, which means abnormal changes in the fat tissues due to repeated insulin injections in the same area of the skin. It includes lipohypertrophy (thickening of adipose tissue) and lipoatrophy (thinning of adipose tissue), and may affect insulin absorption. Rotate insulin injection or infusion sites within the same region to reduce the risk of lipodystrophy.

Q. Can Insulin cause hypoglycemia? How do I prevent it?

Yes, the most common side effect of Insulin is hypoglycemia. It happens more often if you miss or delay your food, drink alcohol, over-exercise or take other antidiabetic medicine along with it. So, do not skip meals and be consistent in the timing and amount of your meals. Take some snacks as per your requirement if you over exercise. Regular monitoring of the blood sugar level is important. Always carry some sugary candies, glucose/glucon-D or fruit juice with you. Take all the medicines prescribed by the doctor on time and consult your doctor if you notice any fluctuations in your blood sugar levels.

Q. Is Insulin given as an injection into a vein (intravenous)?

Yes, sometimes, in specific situations like diabetic ketoacidosis, severe hyperglycemia etc, Insulin may be given as an injection into a vein (intravenous). However, in such cases, it is only given by a doctor, under continuous monitoring of blood sugar levels in a hospital setting.

Q. When does the dosage of Insulin need to be changed?

You should consult your doctor for dose adjustment if you experience weight gain or loss, increased stress, illness, changes in diet such as missed meals or if you are taking alcohol. Your dose may also change if you have recently changed your exercise regime or are taking any medicines. Also, you must be vigilant for certain side effects that you may experience while using Insulin. Your doctor will tell you ways to prevent them. These side effects are usually temporary but if they are very severe, you may need dose modifications.

Q. Does Insulin need to be refrigerated?

Insulin needs to be refrigerated before its first use. Unopened cartridges and unused pre-filled pens of Humalog must be stored in a refrigerator where the temperature is between 2°C to 8°C. Do not freeze and do not use Insulin if it has been frozen. When the cartridge has been inserted into the injection pen, it should not be refrigerated and should be kept at room temperature, below 86°F (30°C) and must be used within 28 days or be discarded, even if they still contain Insulin.

Q. What is Insulin? How is it made?

Insulin is a man-made version of human insulin, produced by the process of biotechnology called recombinant DNA technology. It is sold as a sterile, aqueous, clear, and colorless solution that contains insulin aspart along with other constituents like glycerin, phenol, metacresol, zinc, sodium chloride etc.

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Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Nolte MS. Pancreatic hormones and antidiabetic drugs. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 728-37.
  2. Human Insulin. Bagsvaerd, Denmark: Novo Nordisk A/S; 2012. [Accessed 12 Mar. 2019] (online) Available from:External Link
  3. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 12 Mar. 2019] (online) Available from:External Link
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