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Ibrushil 140mg Capsule

Ibrutinib (140mg)

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Ibrushil 140mg Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). It is also used in chronic lymphocytic leukaemia who have received at least one prior therapy.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 10 Oct 2026 | 01:02 AM (IST)

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30 capsules

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Gurgaon

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General Information

Contains

Ibrutinib (140mg)

Marketer

Shilpa Medicare Ltd

The content is shown in हिंदी

Product introduction

Ibrushil 140mg Capsule is taken in a dose as advised by the doctor. The duration of treatment varies on the basis of your response to treatment. Your doctor may get regular blood tests to check number of blood cells during treatment with this medicine. It is known to reduce the number of blood cells in your blood thereby, increasing the susceptibility to infections. It may cause headache, diarrhea, and nausea as its side effects.

Uses of Ibrushil Capsule

Benefits of Ibrushil Capsule

Blood cancer (Chronic lymphocytic leukemia)
Chronic lymphocytic leukemia (CLL) is a slow-growing blood cancer in which the bone marrow makes abnormal white blood cells that crowd out healthy cells and weaken the immune system. Ibrushil 140mg Capsule helps block signals that cancer cells need to grow and multiply, slowing disease progression and supporting healthier blood cell balance. This helps manage symptoms, maintain immune function, and improve quality of life.

Mantle-cell lymphoma
Mantle-cell lymphoma is a type of non-Hodgkin lymphoma that affects lymph nodes and other parts of the lymphatic system. Ibrushil 140mg Capsule helps stop cancer cells from growing and spreading, allowing for better disease control. This can reduce symptoms, slow disease advancement, and extend periods without disease progression.

Side effects of Ibrushil Capsule

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Ibrushil

Fever
Headache
Fatigue
Musculoskeletal (bone, muscle or joint) pain
Rash
Anemia (low number of red blood cells)
Bruising
Muscle spasm
Hemorrhage
Pneumonia
Cough
Diarrhea
Stomatitis (Inflammation of the mouth)
Nausea
Low blood platelets
Decreased white blood cell count (neutrophils)
Dry eye
High blood pressure
Weight loss
Urinary tract infection
Peripheral edema
Subdural hematoma
Second primary malignancies

How to use Ibrushil Capsule

Take this medicine in the dose and duration as advised by your doctor. Ibrushil 140mg Capsule may be taken with or without food.

How Ibrushil Capsule works

Ibrushil 140mg Capsule is a Bruton's tyrosine kinase inhibitor. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps to stop or slow the spread of cancer cells.

All substitutes for Ibrushil 140mg Capsule

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Take it at the same time every day, either with or without food.
It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.
Take it at the same time every day, either with or without food.
It is advisable to stay hydrated and drink plenty of fluids while taking this medication.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your liver function and blood cell count in your blood.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Ibrushil 140mg Capsule. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Ibrushil 140mg Capsule is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CAUTION

Ibrushil 140mg Capsule should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

UNSAFE

Ibrushil 140mg Capsule may cause side effects that could affect your ability to drive.

Kidney

CAUTION

Ibrushil 140mg Capsule should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Ibrushil 140mg Capsule should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Ibrushil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Apalutamide (Oral Route)

Apalutamide may reduce blood levels of Ibrutinib. Apalutamide may reduce blood levels of Ibrutinib.

Severe

Clarithromycin (Oral Route)

Clarithromycin may raise blood levels of Ibrutinib. Clarithromycin may raise blood levels of Ibrutinib.

Severe

Enzalutamide (Oral Route)

Enzalutamide may reduce blood levels of Ibrutinib. Enzalutamide may reduce blood levels of Ibrutinib.

Severe

Ceritinib (Oral Route)

Ceritinib may raise blood levels of Ibrutinib. Ceritinib may raise blood levels of Ibrutinib.

Severe

Indinavir (Oral Route)

Indinavir may raise blood levels of Ibrutinib. Indinavir may raise blood levels of Ibrutinib.

Frequently asked questions

What is Ibrushil 140mg Capsule used for?

Ibrushil 140mg Capsule is used in the treatment of mantle-cell lymphoma and blood cancer (chronic lymphocytic leukemia). In patients having chronic lymphocytic leukemia, this medicine is given only if they have undergone at least one previous treatment.

Who should not take Ibrushil 140mg Capsule?

There are no absolute contraindications listed, but Ibrushil 140mg Capsule may not be suitable for everyone. Patients with severe liver disease or certain medical conditions may require dose adjustments or close monitoring. Your doctor will closely assess your condition before starting Ibrushil 140mg Capsule treatment.

What warnings of Ibrushil 140mg Capsule should I know about before starting Ibrushil 140mg Capsule?

Ibrushil 140mg Capsule can increase the risk of bleeding, infections, heart rhythm problems, high blood pressure, liver damage, and other serious side effects. Regular monitoring with blood tests and medical checkups is necessary during treatment.

Can Ibrushil 140mg Capsule cause heart problems?

Yes, Ibrushil 140mg Capsule has been linked to irregular heartbeats (arrhythmias), heart failure, and even sudden death in rare cases. Patients with a history of heart disease should inform their doctor before starting Ibrushil 140mg Capsule therapy.

Does Ibrushil 140mg Capsule increase the risk of infections?

Yes, Ibrushil 140mg Capsule can lower your body’s ability to fight infections. Patients may develop fevers, pneumonia, or other serious infections. Any sign of infection should be reported to your doctor right away.

Can Ibrushil 140mg Capsule cause bleeding or bruising?

Yes, bleeding problems such as bruising, nosebleeds, or more serious internal bleeding can happen with Ibrushil 140mg Capsule. If you are taking blood thinners or have a bleeding disorder, you must inform your doctor before starting Ibrushil 140mg Capsule.

What are the serious side effects of Ibrushil 140mg Capsule?

Serious side effects of Ibrushil 140mg Capsule include severe bleeding, life-threatening infections, liver damage, high blood pressure, heart rhythm problems, secondary cancers such as skin cancer, and tumor lysis syndrome (a complication when cancer cells break down too quickly). Seek immediate medical attention if you experience any of these symptoms.

Can Ibrushil 140mg Capsule cause liver damage?

Yes, Ibrushil 140mg Capsule has been linked to hepatotoxicity, which means it can cause liver injury. Doctors usually monitor liver function with blood tests during treatment.

Can Ibrushil 140mg Capsule cause other cancers?

Yes, some patients on Ibrushil 140mg Capsule have developed second cancers, including skin cancers and other types of carcinoma. Skin checks and regular monitoring are recommended during Ibrushil 140mg Capsule treatment.

Fact Box

Chemical Class

Diphenylethers Derivative

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Bruton's tyrosine kinase (BTK) inhibitors

Related lab tests

Complete Blood Count

Cyclin D1

Peripheral Smear Examination

References

User feedback

What are you using Ibrushil Capsule for?

Blood cancer (Chronic lymphocytic leukemia)

100%

How much was the improvement?

Excellent

100%

What were the side-effects while using Ibrushil 140mg Capsule?

No Side Effect

100%

How do you take Ibrushil Capsule?

With or without food

100%

Please rate Ibrushil 140mg Capsule on price

Expensive

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Average

33%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Shilpa Medicare Ltd
Address: 12-6-214/A1, Hyderabad Road, Raichur – 584 135, Karnataka, India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Ibrushil 140mg Capsule. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Ibrushil 140mg Capsule

Ibrushil 140mg Capsule

Payment, Returns & Expiry

Online payment only

7 day free return

Product expires after Jan, 2027

Price Info

Save more with additional offers

General Information

Contains

Marketer

Product introduction

Uses of Ibrushil Capsule

Benefits of Ibrushil Capsule

Side effects of Ibrushil Capsule

How to use Ibrushil Capsule

How Ibrushil Capsule works

All substitutes for Ibrushil 140mg Capsule

Nitib 140mg Capsule

Imbruvica 140mg Capsule

Ibrumart Capsule

Imbruvica 140mg Capsule

Tybriva Capsule

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apalutamide (Oral Route)

Clarithromycin (Oral Route)

Enzalutamide (Oral Route)

Ceritinib (Oral Route)

Indinavir (Oral Route)

Frequently asked questions

What is Ibrushil 140mg Capsule used for?

Who should not take Ibrushil 140mg Capsule?

What warnings of Ibrushil 140mg Capsule should I know about before starting Ibrushil 140mg Capsule?

Can Ibrushil 140mg Capsule cause heart problems?

Does Ibrushil 140mg Capsule increase the risk of infections?

Can Ibrushil 140mg Capsule cause bleeding or bruising?

What are the serious side effects of Ibrushil 140mg Capsule?

Can Ibrushil 140mg Capsule cause liver damage?

Can Ibrushil 140mg Capsule cause other cancers?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

Cyclin D1

Peripheral Smear Examination

References

User feedback

What are you using Ibrushil Capsule for?

How much was the improvement?

What were the side-effects while using Ibrushil 140mg Capsule?

How do you take Ibrushil Capsule?

Please rate Ibrushil 140mg Capsule on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests