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Hydralazine Hydrochloride 20mg Injection
Prescription Required
Product introduction
Hydralazine Hydrochloride 20mg Injection belongs to a class of drugs known as vasodilators. It is used for the treatment of severe or life-threatening hypertension (high blood pressure), when the drug cannot be given orally or when there is an urgent need to lower blood pressure in hospitalised patients.
Hydralazine Hydrochloride 20mg Injection works by relaxing and enlarging certain small blood vessels so that blood flows through them more easily. It is given under the supervision of a healthcare professional and should not be self administered. Certain patients (especially those with marked kidney damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes.
Hydralazine Hydrochloride 20mg Injection should be used immediately after opening. It should not be added to other solutions. It may discolor upon contact with metal; discolored solutions should be discarded. Some of the common side effects of this medicine are headache, loss of appetite, nausea, vomiting, diarrhea and increased heart rate. Please contact your doctor if these side effects do not resolve or persist for a longer duration.
Hydralazine Hydrochloride 20mg Injection works by relaxing and enlarging certain small blood vessels so that blood flows through them more easily. It is given under the supervision of a healthcare professional and should not be self administered. Certain patients (especially those with marked kidney damage) may require a lower dose. Blood pressure should be checked frequently. It may begin to fall within a few minutes after injection, with the average maximal decrease occurring in 10-80 minutes.
Hydralazine Hydrochloride 20mg Injection should be used immediately after opening. It should not be added to other solutions. It may discolor upon contact with metal; discolored solutions should be discarded. Some of the common side effects of this medicine are headache, loss of appetite, nausea, vomiting, diarrhea and increased heart rate. Please contact your doctor if these side effects do not resolve or persist for a longer duration.
Uses of Hydralazine Hydrochloride Injection
Benefits of Hydralazine Hydrochloride Injection
In Hypertension (high blood pressure)
Hydralazine Hydrochloride 20mg Injection is a medicine used to treat severe or life-threatening hypertension (high blood pressure). It increases the flow of blood and oxygen to the heart and other organs by relaxing blood vessels, thereby, lowering your blood pressure. It is usually given as a slow injection by a doctor or healthcare professional.
If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. It must be taken regularly as prescribed to be effective.
If your blood pressure is controlled you are less at risk of having a heart attack, stroke, or kidney problems. It must be taken regularly as prescribed to be effective.
Side effects of Hydralazine Hydrochloride Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Hydralazine Hydrochloride
- Diarrhea
- Headache
- Increased heart rate
- Loss of appetite
- Nausea
- Palpitations
- Vomiting
How to use Hydralazine Hydrochloride Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Hydralazine Hydrochloride Injection works
Hydralazine Hydrochloride 20mg Injection is a potassium channel opener. It works by relaxing blood vessels which lowers blood pressure and allows more blood and oxygen to reach the heart and other organs.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Hydralazine Hydrochloride 20mg Injection.
Pregnancy
CONSULT YOUR DOCTOR
Hydralazine Hydrochloride 20mg Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
SAFE IF PRESCRIBED
Hydralazine Hydrochloride 20mg Injection is safe to use during breastfeeding. Human studies suggest that the drug does not pass into the breastmilk in a significant amount and is not harmful to the baby.
Driving
UNSAFE
Hydralazine Hydrochloride 20mg Injection may cause side effects which could affect your ability to drive.
As Hydralazine Hydrochloride 20mg Injection may cause headaches or lead to difficulty in concentration and this may affect your ability to drive.
As Hydralazine Hydrochloride 20mg Injection may cause headaches or lead to difficulty in concentration and this may affect your ability to drive.
Kidney
CAUTION
Hydralazine Hydrochloride 20mg Injection should be used with caution in patients with severe kidney disease. Dose adjustment of Hydralazine Hydrochloride 20mg Injection may be needed. Please consult your doctor.
Regular monitoring of blood pressure is recommended for better dose adjustment.
Regular monitoring of blood pressure is recommended for better dose adjustment.
Liver
CAUTION
Hydralazine Hydrochloride 20mg Injection should be used with caution in patients with liver disease. Dose adjustment of Hydralazine Hydrochloride 20mg Injection may be needed. Please consult your doctor.
What if you forget to take Hydralazine Hydrochloride Injection?
If you miss a dose of Hydralazine Hydrochloride 20mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine
Quick tips
- Hydralazine Hydrochloride 20mg Injection is usually given as a slow injection into your veins by a doctor or healthcare professional.
- It may cause dizziness. Do not drive or perform activities that require mental focus until you know how Hydralazine Hydrochloride 20mg Injection affects you.
- Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
- Inform your doctor about taking this medicine before undergoing any surgical procedure.
Fact Box
Chemical Class
Phthalazines Derivatives
Habit Forming
No
Therapeutic Class
CARDIAC
Action Class
Potassium channel opener
Interaction with drugs
Taking Hydralazine Hydrochloride with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Neil, Esulide
Moderate
Brand(s): Oxy Triactin, Sioril
Moderate
Brand(s): Pyregin, Alpagin, Bral
Moderate
Patient concerns
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FAQs
Q. What is Hydralazine Hydrochloride 20mg Injection? What is it used for?
Hydralazine Hydrochloride 20mg Injection belongs to a class of medicines known as potassium channel openers. It helps in the removal of potassium from the walls of arteries. This results in increased space in the arteries for the blood to flow easily, thereby reducing the workload of the heart to pump the blood. It also improves the blood and oxygen supply to your heart muscle. It is prescribed to patients with stable angina (heart-related chest pain) who cannot take other medicines (beta blockers, calcium channel antagonist) meant for the treatment of angina.
Q. How long does it take Hydralazine Hydrochloride 20mg Injection to start working?
Hydralazine Hydrochloride 20mg Injection starts working after about an hour of taking the medicine. However, full benefits may be seen only after 4 to 5 days. Consult your doctor if you do not notice any significant improvement in your condition.
Q. What if somebody accidentally takes an excess of Hydralazine Hydrochloride 20mg Injection?
Taking Hydralazine Hydrochloride 20mg Injection in excess may cause low blood pressure and the person may feel weak or dizzy. Also, one may experience irregular or fast heartbeat. In case of an overdose, immediately consult the doctor and seek emergency medical help.
Q. Can I take Hydralazine Hydrochloride 20mg Injection if I am taking aspirin?
You should avoid taking Hydralazine Hydrochloride 20mg Injection and aspirin together. Taking these two medicines together increases the risk of ulcer or bleeding in the mouth, stomach or intestine. Immediately consult your doctor if you notice blood in your stool or vomit while using Hydralazine Hydrochloride 20mg Injection.
Q. Who should not use Hydralazine Hydrochloride 20mg Injection?
People who are allergic to Hydralazine Hydrochloride 20mg Injection or any of its ingredients should avoid using Hydralazine Hydrochloride 20mg Injection. Also, patients who have heart problems such as cardiogenic shock or left ventricular failure with low filling pressure or cardiac decompensation or have a build-up of fluid in the lungs (pulmonary edema) should not use Hydralazine Hydrochloride 20mg Injection. Additionally, it is advised to avoid using Hydralazine Hydrochloride 20mg Injection in people taking medicines to treat erectile dysfunction (e.g., sildenafil, tadalafil and vardenafil) or medicines to treat pulmonary hypertension (e.g., riociguat). This is because these medicines may interfere with the working of Hydralazine Hydrochloride 20mg Injection and affect your blood pressure. Fluctuations in blood pressure could also be due to low blood volume.
Q. Can Hydralazine Hydrochloride 20mg Injection affect my sex life?
No, Hydralazine Hydrochloride 20mg Injection does not affect your sex life. However, it is not recommended to take Hydralazine Hydrochloride 20mg Injection with other medications used for the treatment of erectile dysfunction (e.g., sildenafil or tadalafil) or premature ejaculation (e.g., vardenafil or dapoxetine). Taking these together can lead to a serious drop in your blood pressure. Consult your doctor if you are not sure.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Michel T, Hoffman BB. Treatment of Myocardial Ischemia and Hypertension. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 779-81.
- Benowitz NL. Antihypertensive Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. pp. 178-79.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 658-59.
- Hydralazine Hydrochloride Injection. Shirley, New York: American Regent Inc.; 2013. [Accessed 22 Jan. 2019] (online) Available from:
- Drugs.com. Hydralazine Pregnancy and Breastfeeding Warnings. [Accessed 18 Mar. 2019] (online) Available from:
- Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-S198. [Accessed 18 Mar. 2019] (online) Available from:
Marketer details
Name: Bharat Serums & Vaccines Ltd
Address: 17th Floor, Hoechst House, Nariman Point, Mumbai – 400 021, Maharashtra, India.
Country of origin: India
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