Product introduction
Grandem Injection is an antiemetic medicine used to prevent and treat nausea and vomiting caused by chemotherapy, radiotherapy, or surgical procedures. Grandem Injection works by blocking certain chemical in the brain that triggers vomiting signals, especially during chemotherapy.
Grandem Injection will not relieve other side effects associated with cancer treatments. It is administered under the supervision of a healthcare professional and should be taken as advised by the doctor. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of injections.
The most common side effects of taking this medicine include injection site pain or reaction, headache, constipation, diarrhea, and weakness. These symptoms should disappear when you stop taking the medicine, but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.
Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Als,o tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask for advice from your doctor.
Uses of Grandem Injection
- Treatment of Nausea and vomiting due to chemotherapy
Benefits of Grandem Injection
In Treatment of Nausea and vomiting due to chemotherapy
Grandem Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting associated with cancer treatment such as chemotherapy or radiation therapy. This medicine helps you recover more comfortably from these treatments.
Side effects of Grandem Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Grandem
- Injection site pain
- Constipation
- Diarrhea
- Headache
- Weakness
- Insomnia (difficulty in sleeping)
How to use Grandem Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Grandem Injection works
Grandem Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy).
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Grandem Injection. Please consult your doctor.
Pregnancy
SAFE IF PRESCRIBED
$med_name is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding
SAFE IF PRESCRIBED
Grandem Injection may be safe to use during breastfeeding. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.
Driving
SAFE
Grandem Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Grandem Injection is probably safe to use in patients with kidney disease. Limited data suggest dose adjustment may not be needed.
Liver
SAFE IF PRESCRIBED
Grandem Injection is probably safe to use in patients with liver disease. Limited data suggest dose adjustment may not be needed.
What if you forget to take Grandem Injection?
If you miss a dose of Grandem Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Grandem Injection
₹41/Injection
Graniforce 1mg Injection
Mankind Pharma Ltd
₹33.11/injection
26% cheaper
Integron Injection
Integrated Laboratories Pvt Ltd
₹72.19/injection
60% costlier
Gemirob 1mg Injection
Surewin Healthcare
₹38.44/injection
15% cheaper
Quick tips
- Take meals in small, frequent portions and avoid heavy, greasy, or spicy foods to reduce nausea while on Grandem Injection.
- Stay hydrated with small, frequent sips of water or electrolyte fluids, especially if vomiting has occurred.
- Inform your doctor if you are taking other medicines that affect heart rhythm, as Grandem Injection can influence cardiac conduction in rare cases.
- Do not drive or perform tasks requiring alertness if you feel dizzy or lightheaded after receiving Grandem Injection.
- Report any persistent headache, constipation, or abdominal discomfort to your doctor if symptoms do not improve.
Fact Box
Chemical Class
Indazole- 3- carboxamides
Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL
Action Class
Serotonin 5-HT3 Receptor Antagonists
Interaction with drugs
Taking Grandem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not consume Apomorphine with Granisetron. If concurrent use is essential, please consult your doctor.
Concurrent use may disturb the heart rhythm.
Do not consume Apomorphine with Granisetron. If concurrent use is essential, please consult your doctor.
Concurrent use may disturb the heart rhythm.
Watch out for symptoms such as tremors, fever, diarrhea or agitation and consult your doctor if you experience them. Factors such as old age, chronic heart issues, or low potassium
Careful consideration is advised when taking Levofloxacin with Granisetron. Your doctor may monitor your treatment and adjust the doses as per the observations. Factors such as old
Careful consideration is advised when taking Ciprofloxacin with Granisetron. Your doctor may monitor your treatment and adjust the doses as per the observations. Factors such as ol
Patient concerns
User feedback
What are you using Grandem Injection for?
Vomiting
100%
How much was the improvement?
Excellent
83%
Average
17%
What were the side-effects while using Grandem Injection?
Diarrhea
20%
Constipation
20%
Headache
20%
Sleepiness
20%
Weakness
20%
How do you take Grandem Injection?
Empty stomach
50%
With or witho*
50%
*With or without food
Please rate Grandem Injection on price
Expensive
100%
FAQs
What is Grandem Injection used for?
Grandem Injection is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.
What are the side effects of Grandem Injection?
The most common side effects of Grandem Injection are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.
Is Grandem Injection safe to be used in pregnant women?
Grandem Injection did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Grandem Injection in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.
Is Grandem Injection better than Ondansetron?
Grandem Injection and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Grandem Injection is more effective than Ondansetron. According to some reports, Grandem Injection is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.
Does Grandem Injection cause constipation?
Yes, Grandem Injection may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Granisetron. Place of publication: Hameln Pharma Plus GmBh; 2018. [Accessed on 28 Mar. 2019] (online) Available from:
- PubChem. Granisetron. [Accessed 28 Mar. 2019] (online) Available from:
Marketer details
Name: Aristo Pharmaceuticals Pvt Ltd
Address: Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India. / Regd, Office: 23 -A Shah Industrial Estate, Off Veera Desai Road, Andheri (W), Mumbai-400053 Maharashtra, India
Country of origin: India
Expires on or after: June, 2027
A licensed vendor partner from your nearest location will deliver Grandem Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: June, 2027
A licensed vendor partner from your nearest location will deliver Grandem Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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MRP₹45 9% OFF
₹41
Inclusive of all taxes
1.0 ml in 1 vial
New GST benefit included in this MRP, may differ from label
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