Grandem Injection is an anti-emetic medicine commonly used to control nausea and vomiting caused due to any surgery, cancer drug therapy, or radiotherapy.

Grandem Injection will not relieve other side effects associated with cancer treatments. It is administered under the supervision of a healthcare professional and should be taken as advised by the doctor. It is important that you keep having the injections until your doctor decides it is safe to stop them. After this, your doctor may prescribe tablets instead of injections.

The most common side effects of taking this medicine include injection site pain or reaction, headache, constipation, diarrhea, and weakness. These symptoms should disappear when you stop taking the medicine but if they bother you or do not go away, your doctor may be able to suggest ways of preventing or reducing them.

Before taking this medicine, tell your doctor if you have heart or liver problems or a blockage in your stomach or intestines. Also tell your doctor about other drugs you are using, especially medicines to treat epilepsy, heart problems, cancer, and depression. These may affect, or be affected by, this medicine. If you are pregnant or breastfeeding, ask advice from your healthcare team.

Uses of Grandem Injection

Nausea and vomiting due to chemotherapy

Benefits of Grandem Injection

In Nausea and vomiting due to chemotherapy

Grandem Injection blocks the action of chemicals in the body that can make you feel or be sick. It is often used to prevent nausea and vomiting associated with cancer treatment such as chemotherapy or radiation therapy. This medicine helps you recover more comfortably from these treatments. Grandem Injection is given as an injection by a doctor, in the dose that is best for you, depending on the condition you are being treated for. Do not self-administer this medicine to avoid any undesirable side effects.

Side effects of Grandem Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Grandem

Injection site pain
Constipation
Diarrhea
Headache
Weakness
Insomnia (difficulty in sleeping)

How to use Grandem Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Grandem Injection works

Grandem Injection is an antiemetic medication. It works by blocking the action of a chemical messenger (serotonin) in the brain that may cause nausea and vomiting during anti-cancer treatment (chemotherapy) or after surgery.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Grandem Injection. Please consult your doctor.

Pregnancy

SAFE IF PRESCRIBED

Grandem Injection is generally considered safe to use during pregnancy. Animal studies have shown low or no adverse effects to the developing baby; however, there are limited human studies.

Breast feeding

SAFE IF PRESCRIBED

Grandem Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.

Driving

SAFE

Grandem Injection does not usually affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Grandem Injection is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Grandem Injection may not be needed in these patients. Please consult your doctor.

Liver

SAFE IF PRESCRIBED

Grandem Injection is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Grandem Injection may not be needed in these patients. Please consult your doctor.

What if you forget to take Grandem Injection?

If you miss a dose of Grandem Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

No substitutes found for this medicine

Quick tips

You have been prescribed Grandem Injection for prevention of nausea and vomiting caused after surgery or due to chemotherapy and radiotherapy.
Grandem Injection is given as an injection under the supervision of a doctor.
If you vomit within one hour of taking a dose, take another dose.
Avoid heavy meals and try eating small nourishing snacks throughout the day. Also, sip water regularly to help avoid dehydration.

Fact Box

Chemical Class

Indazole Derivative

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Action Class

Serotonin antagonists (5-HT3 antagonists)

Interaction with drugs

Taking Grandem with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Codeine

Brand(s): Acicod, Montokuf, Codine Sulphate

Serious

Dextropropoxyphene

Brand(s): Parvodex

Serious

Nalbuphine

Brand(s): Nalfy, Nacphin, Ruffy

Serious

Pentazocine

Brand(s): Wintal

Serious

View all interactions

Patient concerns

NAUSEA AND VOMITING DUE TO COLD

Dr. Sunil Sekhri

Diabetology

Tab Domstal 1 tab Stat and keep yourself warm

Vomiting, nausea neck pain backside

Dr. Vijay Verma

ENT

Neck pain may be due to nausea NAD vomiting Visit physician for the same

I am in the first month of pregnancy and I am experiencing nausea, vomiting, stomach pain (moderate to severe) as well as discomfort. Current medications is Susten SR 200 (OD), Duvadilan retard (OD), Doxinate (BD), Folverine D (OD), Fertigyn 500 (1 amp weekly) and aciloc 150 (BD). What should I do to ease my situation. Please suggest

Dr. Suman Rao

Obstetrics and Gynaecology

The med suggested are to support of pregnancy and for acidity and nausea and vomiting. Continue the same. You can upgrade the med for vomiting after consulting your

Vomiting nausea problem and fever

Dr. Gopal Bansilal Samdani

Paediatrics

Monitor temperature of Patient. If Patient has fever place a cool, damp washcloth on your child's forehead. Give your Patient a lukewarm tub bath or a sponge bath. Give a sponge bath as follows: - ? Use lukewarm water [90?F (32.2?C) to 95?F (35?C)]. Do not use cold water, ice, or rubbing alcohol, which will lower the child's body temperature too quickly. ? Sponge for 20 to 30 minutes. ? Stop if the child starts to shiver. If your child doesn't like the sponge bath or doesn't feel better after the bath, there is no need to give another one. You can use paracetamol also along with above measures to control fever till you consult Dr. will determine underlying disorders by clinical examination which range from mild conditions to the most serious of bacterial and viral illnesses and will prescribe medicines accordingly. Advice given without doing clinical examination can be imperfect or some time harmful to patient.

User feedback

What are you using Grandem Injection for?

Vomiting

100%

How much was the improvement?

Excellent

83%

Average

17%

What were the side-effects while using Grandem Injection?

Sleepiness

20%

Weakness

20%

Constipation

20%

Diarrhea

20%

Headache

20%

How do you take Grandem Injection?

With or witho*

50%

Empty stomach

50%

*With or without food

Please rate Grandem Injection on price

Expensive

100%

FAQs

Q. What is Grandem Injection used for?

Grandem Injection is an antiemetic medicine used to treat and prevent nausea or vomiting caused after any surgical procedure or due to certain medicines, stomach upset, or cancer treatment. It also prevents nausea due to motion sickness to some extent.

Q. What are the side effects of Grandem Injection?

The most common side effects of Grandem Injection are sleepiness, weakness, headache, constipation and diarrhea. However, these are not usually bothersome and resolve in some time on their own. Consult your doctor, if the symptoms worry you or persist for a longer duration. Your doctor will suggest ways to cope up with these side effects and to prevent them in future.

Q. Is Grandem Injection safe to be used in pregnant women?

Grandem Injection did not show any adverse effects in research studies done on animals. However, since the safety and efficiency of Grandem Injection in pregnant women is unknown. It is not recommended to be used in women who are pregnant women or if you are planning to conceive unless prescribed by your doctor.

Q. Is Grandem Injection better than Ondansetron?

Grandem Injection and Ondansetron belong to the same class of medicines, that is serotonin 5-HT3 receptor antagonists. Both these medicines help prevent nausea and vomiting effectively. However, some studies suggest that Grandem Injection is more effective than Ondansetron. According to some reports, Grandem Injection is comparatively well tolerated, quicker in action and alleviates nausea and vomiting relatively faster.

Q. Does Grandem Injection cause constipation?

Yes, Grandem Injection may cause constipation as one of the common side effects. However, this is usually not bothersome. Taking a fiber-rich diet can enhance your digestion and avoid constipation. You may also consider taking laxatives for relief and drink plenty of water too. Avoid drinking alcohol as it may worsen your constipation. If you still face issues, please consult your doctor to know about ways to treat it.

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Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Granisetron. Place of publication: Hameln Pharma Plus GmBh; 2008 [revised 8 Oct 2018]. [Accesses on 28 Mar. 2019] (online) Available from:
PubChem. Granisetron. [Accessed 28 Mar. 2019] (online) Available from:
Drugs.com. Granisetron Pregnancy and Breastfeeding Warnings. [Accessed 28 Mar. 2019] (online) Available from:

Manufacturer/Marketer address

Mercantile Chamber, 3rd Floor, 12, J.N. Heredia Marg, Ballard Estate, Mumbai – 400 001, India.

Country of origin: India
Expires on or after: September, 2023

A licensed vendor partner from your nearest location will deliver Grandem Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India