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MD (Pharmacology), MBBS
Last updated
13 Dec 2024 | 01:00 AM (IST)

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Gramonex Injection

Prescription Required
Storage
Store below 30°C

Product introduction

Gramonex Injection is a combination of two antibiotics that effectively treat diarrhea and dysentery. It kills the microorganisms to treat the infection.

Gramonex Injection is a prescription medicine that must be administered under the supervision of a healthcare professional. Do not miss any scheduled appointments for taking this medicine. The treatment must be completed even if you feel better to ensure a complete recovery.

Gramonex Injection may lead to some side effects such as nausea, vomiting, stomach pain, loss of appetite, headache, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. You may also experience mild injection site reactions such as pain, swelling, and redness. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must seek immediate medical help.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.


Uses of Gramonex Injection


Side effects of Gramonex Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Gramonex

  • Nausea
  • Dryness in mouth
  • Metallic taste
  • Headache

How to use Gramonex Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gramonex Injection works

Gramonex Injection is a combination of two antibiotics: Nalidixic Acid and Metronidazole. Nalidixic Acid works by preventing the bacterial cells from dividing and repairing, thereby killing the bacteria. Metronidazole kills parasites and anaerobic bacteria that cause infections by damaging their DNA. Together, they treat your infection effectively.

Safety advice

Alcohol
UNSAFE
Consuming alcohol while taking Gramonex Injection may cause symptoms such as flushing, increased heart beat, nausea, thirst, chest pain and low blood pressure (Disulfiram reaction).
Pregnancy
CONSULT YOUR DOCTOR
Gramonex Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breast feeding
CAUTION
Gramonex Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from her body.
If a single dose of Gramonex Injection is used, it is recommended to hold breastfeeding for 12-24 hours to allow the removal of the drug.
Driving
UNSAFE
Gramonex Injection may cause side effects which could affect your ability to drive.
Gramonex Injection may make you feel sleepy, dizzy, confused. You may have hallucinations, fits (convulsions) or temporary eyesight problems (such as blurred or double vision) affecting your ability to drive.
Kidney
CAUTION
Gramonex Injection should be used with caution in patients with kidney disease. Dose adjustment of Gramonex Injection may be needed. Please consult your doctor.
Regular monitoring of kidney function tests is advised if this medicine is to be taken for a long time.
Liver
CAUTION
Gramonex Injection should be used with caution in patients with liver disease. Dose adjustment of Gramonex Injection may be needed. Please consult your doctor.

What if you forget to take Gramonex Injection?

If you miss a dose of Gramonex Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.
No substitutes found for this medicine

Quick tips

  • Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
  • Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you. 
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Gramonex Injection if you have blood in your stool or if you are severely constipated.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Gramonex Injection as it may irritate your stomach and also cause excessive drowsiness.
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.
  • Your doctor has prescribed this combination medicine for the treatment of diarrhea and dysentery.
  • Diarrhea can cause dehydration. Drink plenty of fluids to help rehydrate you. 
  • Consult your doctor if your diarrhea lasts for more than 48 hours.
  • Do not use Gramonex Injection if you have blood in your stool or if you are severely constipated.
  • It may cause dizziness and sleepiness. Do not drive or do anything that requires mental focus until you know how it affects you.
  • Avoid consuming alcohol when taking Gramonex Injection as it may irritate your stomach and also cause excessive drowsiness.
  • Notify your doctor if you feel pain in your tendons, numbness, or tingling sensations.
  • Inform your doctor if you are pregnant or planning to conceive or breastfeeding.

Fact Box

Habit Forming
No
Therapeutic Class
GASTRO INTESTINAL

Patient concerns

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Diarrhea and dysentery last 15 days I had taken levofoxcin+ornidazol bd for 5 days along refaximin 400 tab bd for 5 day but it is start again
Dr. Sfurti Mann
Internal Medicine
Get a colonoscopy done for chronic Diarrhea
For diarrhea which antibiotic is good for kids and for dysentery which antibiotic is good for kids?
Dr. Gopal Bansilal Samdani
Paediatrics
There are many underlying causes of Patient?s symptoms. Different cause needs different treatment. Specific treatment cannot be given unless we establish exact underlying cause. Final and perfect diagnosis cannot be done without doing clinical examination of patient. Please consult me or any other Paediatrician. will take detail history and will examine patient in detail. All information will be used to determine exact underlying cause of problem. Depending upon cause will give opinion and prescribe you treatment. At time may ask you relevant investigations if necessary. Patient may need antibiotics and/or other prescription drugs. It is mandatory for the customer to have a prescription for the prescription medicines he/she is procuring. Valid prescription cannot be given without diagnosis and clinical examination. Advice given without doing clinical examination can be imperfect or some time harmful to patient.
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FAQs

What if I don't get better after using Gramonex Injection?

Inform your doctor if you don't feel better after finishing the full course of treatment. Also, inform him if your symptoms are getting worse while using this medicine.

Can I stop taking Gramonex Injection when I feel better?

No, do not stop taking Gramonex Injection and complete the full course of treatment even if you are feeling better. Your symptoms may improve before the infection is completely cured.

What if I miss my dose?

Take Gramonex Injection as soon as you remember it. However, do not take it if it's almost time for your next dose. Also, do not take an extra dose to make up for your missed dose.
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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. ScienceDirect. Nalidixic Acid. [Accessed 01 Apr.] (online) Available from:External Link
  2. ScienceDirect. Metronidazole. [Accessed 01 Apr.] (online) Available from:External Link
  3. Metronidazole. Norfolk: Baxter Healthcare Ltd.; 12 Nov. 2006 [revised Nov 2017]. [Accessed 15 Apr. 2019] (online) Available from:External Link

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