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Gracef 250mg Injection

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 31 Mar 2026 | 02:31 PM (IST)
Gracef 250mg Injection is an antibiotic medicine used to treat bacterial infections in your body. It is effective in infections of the brain, lungs, ear, urinary tract, skin and soft tissues, bones and joints, blood, and heart. It is also used to prevent infections during surgery.
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General Information

The content is shown in English
Gracef 250mg Injection image
Gracef 250mg Injection image

Product introduction

Gracef 250mg Injection fights and stops the growth of many types of bacteria. This helps to improve your symptoms and cure the underlying infection. It is given as a drip (intravenous infusion) or as an injection directly into a vein or a muscle under the supervision of a healthcare professional. Your doctor will decide the correct dose for you. You should use this medicine regularly at evenly spaced intervals as per the schedule prescribed by your doctor. Do not skip any doses and finish the full course of treatment even if you feel better. Stopping the medicine too early may lead to the infection returning or worsening.

The most common side effects of this medicine include rash and diarrhea. Some people may develop temporary redness or pain at the site of injection. These side effects are usually mild but let your doctor know if they bother you or last more than a few days.

Before using it, you should tell your doctor if you are allergic to any antibiotics, and if you have any liver or kidney problems. You should also let your healthcare team know all other medicines you are taking as they may affect, or be affected by this medicine. Pregnant and breastfeeding mothers should consult their doctor before using it.

Uses of Gracef Injection

Benefits of Gracef Injection

Bacterial infections
Gracef 250mg Injection is the injection form of an antibiotic medicine that kills the infection causing bacteria in your body. It is often injected by a doctor or a nurse either into a vein or a muscle. This medicine is used to treat many different types of infections such as those of the brain (meningitis), lungs (pneumonia), ear, abdomen, urinary tract, bones and joints, skin, blood, and heart. This medicine usually makes you feel better within a few days. Follow your doctor's instructions carefully to get maximum benefit.

Side effects of Gracef Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gracef
  • Rash
  • Allergic reaction
  • Injection site reaction
  • Diarrhea

How to use Gracef Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Gracef Injection works

Gracef 250mg Injection is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

Quick tips

  • Your doctor has prescribed Gracef 250mg Injection to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
  • Discontinue Gracef 250mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
  • Your doctor has prescribed Gracef 250mg Injection to cure your infection and improve your symptoms.
  • Do not skip any doses and finish the full course of treatment even if you feel better. Stopping it early may make the infection harder to treat.
  • Take it with food to avoid an upset stomach.
  • Diarrhea may occur as a side effect but should stop when your course is complete. Inform your doctor if it does not stop or if you find blood in your stools.
  • Avoid consuming alcohol while taking Gracef 250mg Injection as it may cause increased side effects.
  • Discontinue Gracef 250mg Injection and inform your doctor immediately if you get a rash, itchy skin, swelling of face and mouth, or have difficulty in breathing.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Gracef 250mg Injection. Please consult your doctor.
Pregnancy

Pregnancy

SAFE IF PRESCRIBED
Gracef 250mg Injection is generally considered safe to use during pregnancy. Animal studies do not indicate harmful effects. However, there are limited human studies.
Breast feeding

Breast feeding

CAUTION
Gracef 250mg Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Avoid prolonged use of Gracef 250mg Injection, since it may have possible effects such as rash and diarrhea.
Driving

Driving

UNSAFE
Gracef 250mg Injection may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney

Kidney

CAUTION
Gracef 250mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Liver

Liver

SAFE IF PRESCRIBED
Gracef 250mg Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Gracef with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Ceftazidime. Please consult your doctor. Ceftazidime may reduce the efficacy of Cholera Vaccine (Inactivated).
Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Ceftazidime may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine. Ceftazidime may reduce the efficacy of Purified Vi Polysaccharide Typhoid Vaccine.
Moderate

Amikacin (Injection Route)

Your doctor may monitor your kidney function regularly.
Moderate

Indomethacin (Oral Route)

If concurrent use is essential, watch out for symptoms such as numbness, tingling, burning pain, nausea, vomiting or diarrhea and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations. Indomethacin may slow down the removal of Ceftazidime from the body.
Moderate

Indomethacin (Injection Route)

If concurrent use is essential, watch out for symptoms such as numbness, tingling, burning pain, nausea, vomiting or diarrhea and consult your doctor if you experience them. They may monitor your treatment and adjust the doses as per the observations. Indomethacin may slow down the removal of Ceftazidime from the body.

Frequently asked questions

Gracef 250mg Injection is active against pseudomonas, anaerobes, and staphylococcus bacteria. It may not be effective against methicillin- resistant Staphylococcus aureus (MRSA).
Gracef 250mg Injection is administered under the supervision of a trained healthcare professional or a doctor and should not be self administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Gracef 250mg Injection.
Yes, the use of Gracef 250mg Injection can cause diarrhea. Gracef 250mg Injection is an antibiotic which kills the harmful bacteria. However, it also affects the helpful bacteria in your stomach or intestine and causes diarrhea. If diarrhea persists, talk to your doctor about it.
Usually, Gracef 250mg Injection starts working soon after you take it. However, it may take some days to kill all the harmful bacteria and relieve your symptoms completely.
Inform your doctor if you do not feel better even after finishing the full course of treatment. You must also inform your doctor if the symptoms get worse while using this medicine.
Gracef 250mg Injection is effective if used in the dose and duration advised by your doctor. Do not stop taking it even if you see improvement in your condition. If you stop using Gracef 250mg Injection too early, the symptoms may return or worsen.

Fact Box

Chemical Class

Cephalosporins

Habit Forming

No

Therapeutic Class

ANTI INFECTIVES

Action Class

Third-Generation Cephalosporins

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 228-29.
  2. Chaves RG, Lamounier JA. Breastfeeding and maternal medications. J Pediatr (Rio J). 2004;80(5 Suppl):S189-98. [Accessed 29 Mar. 2019] (online) Available from:
  3. Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Grace Drugs & Pharmaceuticals
Address: 13, H.V.E.S. Complex, K.S.Lane Sultan Bazar, Hyderabad Andhara Pradesh-500095 India

Vendor Details

Country of origin: India
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