Gloxitel 40 Tablet DT is a medicine used to treat high blood pressure and heart failure. Lowering blood pressure helps to prevent future heart attacks and strokes. This medicine is also effective in preserving kidney function in patients with diabetes.
Gloxitel 40 Tablet DT can be prescribed either alone or in combination with other medicines. It may be taken with or without food during the day or at night. However, try to take it at the same time each day to get the most benefit. It is important to continue taking it regularly even if you feel well or if your blood pressure is controlled. Most people with high blood pressure do not feel ill, but if you stop taking this medicine, your condition could get worse. This is a widely used medicine and is considered safe for long-term use.
Making some changes in your lifestyle will also help lower your blood pressure. These may include regular exercise, losing weight, smoking cessation, reducing alcohol intake, and reducing the amount of salt in your diet as advised by your doctor.
This medicine is tolerated well by most patients and has few side effects. However, it may cause hypotension (low blood pressure) in some people. Let your doctor know if you experience any of these side effects. They may be able to help by reducing the dosage or by prescribing you an alternate medicine.
Before taking this medicine, let your doctor know if you have any kidney or liver problems. Pregnant or breastfeeding mothers should also consult their doctor before taking it. Your doctor may check your kidney function, blood pressure, and potassium levels in your blood at regular intervals while you are taking this medicine.
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Gloxitel
Upper respiratory tract infection
Back pain
Diarrhea
Intermittent claudication
Sinus inflammation
Skin ulcer
How to use Gloxitel Tablet DT
Take this medicine in the dose and duration as advised by your doctor. Dissolve it in a glass of water before taking it. Gloxitel 40 Tablet DT may be taken with or without food, but it is better to take it at a fixed time.
How Gloxitel Tablet DT works
Gloxitel 40 Tablet DT is an angiotensin receptor blocker (ARB). It relaxes blood vessels by blocking the action of a chemical that usually makes blood vessels tighter. This lowers the blood pressure, allowing the blood to flow more smoothly to different organs and the heart to pump more efficiently.
Safety advice
Alcohol
UNSAFE
It is unsafe to consume alcohol with Gloxitel 40 Tablet DT.
Pregnancy
CONSULT YOUR DOCTOR
Gloxitel 40 Tablet DT is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Information regarding the use of Gloxitel 40 Tablet DT during breastfeeding is not available. Please consult your doctor.
Driving
UNSAFE
Gloxitel 40 Tablet DT may decrease alertness, affect your vision or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
Kidney
CAUTION
Gloxitel 40 Tablet DT should be used with caution in patients with severe kidney disease. Dose adjustment of Gloxitel 40 Tablet DT may be needed. Please consult your doctor. However, inform your doctor if you have an underlying kidney disease. Regular monitoring of blood pressure, creatinine, and potassium levels may be advised while you are taking this medicine.
Liver
CAUTION
Gloxitel 40 Tablet DT should be used with caution in patients with liver disease. Dose adjustment of Gloxitel 40 Tablet DT may be needed. Please consult your doctor. Use of Gloxitel 40 Tablet DT is not recommended in patients with severe liver disease.
What if you forget to take Gloxitel Tablet DT?
If you miss a dose of Gloxitel 40 Tablet DT, skip it and continue with your normal schedule. Do not double the dose.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
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Should Gloxitel 40 Tablet DT be taken in the morning or at night?
Gloxitel 40 Tablet DT is generally recommended to be taken once daily, either in the morning or in the evening. Consider taking it at the same time each day as it will help you to remember taking it.
How long does it take for Gloxitel 40 Tablet DT to work?
You may see an improvement within a few days. But, the maximum benefit can be seen within 4-8 weeks of starting treatment.
My blood pressure is now controlled. Can I stop taking Gloxitel 40 Tablet DT now?
No, do not stop taking Gloxitel 40 Tablet DT without consulting your doctor even if your blood pressure is controlled. Stopping it suddenly may increase your blood pressure which could be detrimental for you. Gloxitel 40 Tablet DT does not cure high blood pressure but controls it. So, you may have to take the medicine lifelong. Talk to your doctor if you have any concerns.
If I have some kidney problem, can I take Gloxitel 40 Tablet DT? Can it further deteriorate my kidney function?
You can take Gloxitel 40 Tablet DT if it has been advised by your doctor. Your doctor may ask you to get regular tests done (potassium and creatinine levels) in order to monitor your kidney function. Gloxitel 40 Tablet DT may cause worsening of kidney function, therefore you should contact your doctor in case you notice swelling in your feet, ankles, or hands or unexplained weight gain.
I am overweight and the doctor has prescribed me Gloxitel 40 Tablet DT for blood pressure control. I am bothered that Gloxitel 40 Tablet DT can increase my weight. Is it true?
No, do not worry since Gloxitel 40 Tablet DT is not known to cause weight gain. In fact in animal studies Gloxitel 40 Tablet DT has been found to decrease fat tissue.
Does Gloxitel 40 Tablet DT affect blood glucose levels in diabetics?
Gloxitel 40 Tablet DT may lower blood glucose levels in patients with diabetes. Therefore, it is essential to keep a regular track of your blood glucose levels. Talk to your doctor if you are a diabetic because the dose of insulin or antidiabetic medicines may need adjustment.
Can the use of Gloxitel 40 Tablet DT cause hyperkalemia (increased potassium level in blood)?
Yes, Gloxitel 40 Tablet DT can cause hyperkalemia (increased potassium level in blood). A regular monitoring of blood potassium levels may be advised by your doctor while taking this medicine.
Does Gloxitel 40 Tablet DT work by causing excessive urination?
No, Gloxitel 40 Tablet DT does not cause excessive urination and does not belong to the diuretic class of medicines. Gloxitel 40 Tablet DT works by relaxing the blood vessels by blocking the effect of a substance known as angiotensin II. This substance is responsible for increasing the blood pressure by narrowing down the blood vessels.
Do I need to follow any precautions if I take ibuprofen and Gloxitel 40 Tablet DT together?
If you are taking ibuprofen and Gloxitel 40 Tablet DT together, you should continuously keep a check on your blood pressure and kidney function. Gloxitel 40 Tablet DT may enhance the side effects of ibuprofen which may further cause water retention, especially in patients taking Gloxitel 40 Tablet DT for heart failure. Ibuprofen may interfere with the working of Gloxitel 40 Tablet DT and decrease its efficiency at lowering blood pressure.
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References
Pfeffer MA, Opie LH. Inhibitors of the Renin-Angiotensin-Aldosterone System. In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 157.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1322-23.
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