Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Giride M 1 mg/500 mg Tablet SR is to be taken with food. Giride M 1 mg/500 mg Tablet SR may cause stomach upset if taken empty stomach.
Giride M 1 mg/500 mg Tablet SR is a combination of two antidiabetic medicines: Glimepiride and Metformin. Glimepiride is a sulfonylurea which works by increasing the amount of insulin released by the pancreas in order to lower the blood glucose. Metformin is a biguanide which works by lowering glucose production in the liver, delaying glucose absorption from intestines and increasing the body's sensitivity to insulin.
You have been prescribed this combination medicine as it can control blood sugar better than metformin alone.
You should continue to exercise regularly, eat a healthy diet, and take your other diabetes medicines along with Giride M 1 mg/500 mg Tablet SR.
Take it with food to lower your chance of having an upset stomach.
Monitor your blood sugar level regularly while you are taking this medicine.
Inform your doctor about your diabetes treatment if you are due to have surgery under a general anaesthetic.
It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol or if you delay or miss a meal.
Tell your doctor immediately if you experience any deep or rapid breathing, or persistent nausea, vomiting, and stomach pain as Giride M 1 mg/500 mg Tablet SR may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
Taking metformin with alcohol can cause lactic acidosis and you may experience malaise, respiratory distress, slow or irregular heartbeat, sleepiness, stomach upset, or other unusual symptoms.
WEIGH RISKS VS BENEFITS
Giride M 1 mg/500 mg Tablet SR may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Giride M 1 mg/500 mg Tablet SR is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
Your ability to drive may be affected if your blood sugar is low or high. If this happens, do not drive.
Giride M 1 mg/500 mg Tablet SR should be used with caution in patients with kidney disease. Dose adjustment of Giride M 1 mg/500 mg Tablet SR may be needed. Please consult your doctor. Use of Giride M 1 mg/500 mg Tablet SR is, however, not recommended in patients with severe kidney disease. Regular monitoring of kidney function test is advisable while you are taking this medicine.
Giride M 1 mg/500 mg Tablet SR should be used with caution in patients with liver disease. Dose adjustment of Giride M 1 mg/500 mg Tablet SR may be needed. Please consult your doctor. Giride M 1 mg/500 mg Tablet SR is generally started with low dose in patients with mild to moderate liver disease and its use is not recommended in patients with severe liver disease.