Flexital 400mg Tablet

Reviewed By Dr. Rajeev Sharma, MBA, MBBS

Last updated on 02 Feb 2026 | 02:48 PM (IST)

Flexital 400mg Tablet is used to treat peripheral vascular disease (poor circulation to the arms and legs) and intermittent claudication (pain on walking or at rest caused by poor circulation to the legs). It works by increasing the blood flow to the arms and legs.

Genuine

Authenticity Assured

Prescription

required

₹70.9 MRP ₹78.510% off

We do not facilitate sale of this product at present

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

Save more with additional offers

Pay with Amazon Pay Balance and get cashback up to Rs. 100 with minimum cashback of Rs. 20

Earn cashback up to Rs. 100 with Amazon Pay Later

Assured cashback up to ₹300 on minimum payment of ₹300 using Paytm UPI*

10% cashback up to 200 on Min Transaction of Rs.1000, for first time users of Airtel Payments Bank.

Get cashback up to ₹500

Get upto Rs.500 Cashback on minimum transaction of Rs.999/- with Mobikwik Wallet.

Get upto Rs.150 Cashback

General Information

Contains

Pentoxifylline (400mg)

Marketer

Sun Pharmaceutical Industries Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Take Flexital 400mg Tablet exactly as prescribed by your doctor. It works best when taken regularly, as it helps improve blood flow over time rather than giving instant relief. Do not skip doses or stop the medicine on your own, even if symptoms start to improve, as this may reduce its benefit. If you miss a dose, take it as soon as you remember unless it is almost time for the next dose, do not double the dose.

Common side effects of Flexital 400mg Tablet may include flushing, headache, dizziness, drowsiness, nervousness, tremor, and sleep disturbances such as insomnia. Some people may experience stomach-related discomfort like abdominal pain, bloating, indigestion (dyspepsia), nausea, vomiting, or diarrhea. Blurred vision may also occur. These effects are usually mild and settle as the body adjusts to the medicine. Consult your doctor if any side effect persists, worsens, or becomes bothersome.

Flexital 400mg Tablet should be used with caution in people who have heart disease, low blood pressure, bleeding disorders, or a history of stroke. Inform your doctor if you have liver or kidney problems, as dose adjustment may be required. It is not recommended for patients with recent bleeding, recent heart attack, or allergy to methylxanthines (such as caffeine or theophylline). Use during pregnancy or breastfeeding should be only if clearly advised by a doctor.

Uses of Flexital Tablet

Peripheral vascular disease
Intermittent claudication

Benefits of Flexital Tablet

Peripheral vascular disease
Peripheral vascular disease refers to the condition of disturbed blood circulation in blood vessels. Flexital 400mg Tablet prevents blood from clotting inside the veins and arteries. This helps the blood flow freely around your body thereby preventing a heart attack or stroke (or deep vein thrombosis or pulmonary embolism). It helps prevent the formation of blood clots and also prevents the existing ones from growing bigger in size. Make appropriate lifestyle changes (such as eating healthy and staying active) to maximize the effectiveness of this medicine.

Intermittent claudication
Intermittent claudication refers to muscle pain on mild exertion (ache, cramp, numbness or sense of fatigue), classically in the calf muscle, which occurs during exercise or even walking, and it gets better with a short period of rest. Flexital 400mg Tablet helps relieve this pain in the legs that is caused due to disturbed blood supply in the legs. It helps prevent formation of blood clots, improves blood flow and maintains free flowing of blood in your body.

Side effects of Flexital Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Flexital

Bloating
Flushing (sense of warmth in the face, ears, neck and trunk)
Nausea
Stomach discomfort
Vomiting
Dizziness
Angina (heart related chest pain)
Arrhythmia (irregular heartbeats)
Indigestion
Nervousness
Drowsiness
Headache
Insomnia (difficulty in sleeping)
Tremors
Blurred vision

How to use Flexital Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Flexital 400mg Tablet should be taken with or after food.

How Flexital Tablet works

Flexital 400mg Tablet is a peripheral vasodilator. It works by decreasing the thickness (viscosity) of blood, allowing it to pass more easily through the blood vessels. This effect is beneficial in peripheral vascular disease, where the blood vessels in the arms and legs are narrowed.

Quick tips

Take it as per dose and duration suggested by your doctor.
Do not drive or perform activities that require mental focus until you know how Flexital 400mg Tablet affects you.
Your doctor may get regular blood tests done to monitor liver function while taking this medicine.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.
Take it with food, preferably at the same time everyday to avoid missing a dose.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Flexital 400mg Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Flexital 400mg Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Flexital 400mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

SAFE

Flexital 400mg Tablet does not usually affect your ability to drive.

Kidney

CAUTION

Flexital 400mg Tablet should be used with caution in patients with kidney disease. Dose adjustment may be needed.

Liver

CAUTION

Flexital 400mg Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Flexital with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Aminophylline (Oral Route)

Do not consume Aminophylline with Pentoxifylline. If concurrent use is essential, watch out for symptoms such as nausea, palpitations or headaches and consult your doctor if you experience them. They may monitor and adjust the dose of Aminophylline accordingly. Pentoxifylline may raise blood levels of Aminophylline.

Severe

Ciprofloxacin (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Ciprofloxacin may raise blood levels of Pentoxifylline.

Severe

Ciprofloxacin (Injection Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Ciprofloxacin may raise blood levels of Pentoxifylline.

Severe

Phenindione (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations.

Severe

Aminophylline (Injection Route)

Frequently asked questions

What is Flexital 400mg Tablet used for?

Flexital 400mg Tablet is used to improve blood flow in people with circulation problems, especially those with peripheral arterial disease, which can cause leg pain or cramps when walking. It works by making the blood less thick and easier to flow through small blood vessels.

How does Flexital 400mg Tablet help with poor blood circulation?

Flexital 400mg Tablet improves blood flow by reducing blood viscosity (thickness), and helping red blood cells move more easily through narrow blood vessels. This helps increase oxygen delivery to affected areas, reducing pain and discomfort during walking.

Who should not take Flexital 400mg Tablet?

Individuals should not take Flexital 400mg Tablet if they have had recent bleeding in the brain or eyes, or if they are allergic to pentoxifylline, or similar substances like caffeine, or theophylline. Always inform your doctor about your full medical history before starting this medicine.

Can Flexital 400mg Tablet cause serious allergic reactions?

Yes, although they are rare, serious allergic reactions of Flexital 400mg Tablet include swelling, difficulty breathing, or severe rash. If you notice these symptoms, stop the medicine immediately and seek urgent medical help.

Is Flexital 400mg Tablet safe for people with heart problems?

Flexital 400mg Tablet has been used in people with heart and circulation issues, but in some cases, it may cause chest pain, low blood pressure, or irregular heartbeat. If you have heart disease, your doctor will monitor you closely while on this medicine.

Does Flexital 400mg Tablet increase the risk of bleeding?

Flexital 400mg Tablet may increase bleeding risk, especially if you have bleeding disorders, stomach ulcers, recent surgery, or are taking other blood-thinning medicines. Your doctor may check your blood counts, bleeding time, and clotting time regularly.

Fact Box

Chemical Class

Xanthine derivative

Habit Forming

Therapeutic Class

CARDIAC

Action Class

Hemorrheologic Agents

References

Katzung BG, Chatterjee K. Vasodilator & the Treatment of Angina Pectoris. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 205.
Gersh BJ, Opie LH. Which Therapy for Which Condition? In: Opie LH, Gersh BJ, editors. Drugs for the Heart. 8th ed. Philadelphia, Pennsylvania: Elsevier Saunders; 2013. p. 528.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1089-90.
Pentoxifylline. Guildford, Surrey: SANOFI; 2002 [revised 25 May 2016]. [Accessed 25 Jan. 2019] (online) Available from:
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Pentoxifylline. [Updated 2018 Oct 31]. [Accessed 19 Feb. 2020] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
Pentoxifylline [Patient Information Leaflet]. Ankleshwar: Gujarat: Sanofi India Limited; 2015. [Accessed 06 Apr. 2024] (online) Available from:
Memorial Sloan Kettering Cancer Center; 2022. [Accessed 02 Feb. 2026] (online). Available from:
Pentoxifyllin. Burbank, CA: Bryant Ranch Prepack; 2025. [Accessed 02 Feb. 2026] (online). Available from:

User feedback

Patients taking Flexital 400mg Tablet

Thrice A Day

52%

Once A Day

43%

Twice A Day

What are you using Flexital Tablet for?

Peripheral vascular disease

46%

Intermittent claudication

46%

Others

How much was the improvement?

Poor

44%

Average

33%

Excellent

22%

What were the side-effects while using Flexital 400mg Tablet?

No Side Effect

100%

How do you take Flexital Tablet?

With food

100%

Please rate Flexital 400mg Tablet on price

Average

67%

Not Expensive

33%

Want to know more

We provide you with authentic, trustworthy and relevant information

Have issue with the content

Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Sun Pharmaceutical Industries Ltd
Address: Plot no 107/108,Namli block , Ranipool, East Sikkim 737135 || Khasra No. 1335-1340,Near EPIP- I, Vill - Bhatoli Kalan ,Baddi, Solan, Himachal Pradesh, 173205

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Provide right medicines

Prescriptions are complex documents. We proof read and recheck at various steps to provide you the right medication in the correct form and dose

In accordance with the law

Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945

Flexital 400mg Tablet

Save more with additional offers

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Flexital Tablet

Benefits of Flexital Tablet

Side effects of Flexital Tablet

How to use Flexital Tablet

How Flexital Tablet works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Aminophylline (Oral Route)

Ciprofloxacin (Oral Route)

Ciprofloxacin (Injection Route)

Phenindione (Oral Route)

Aminophylline (Injection Route)

Frequently asked questions

What is Flexital 400mg Tablet used for?

How does Flexital 400mg Tablet help with poor blood circulation?

Who should not take Flexital 400mg Tablet?

Can Flexital 400mg Tablet cause serious allergic reactions?

Is Flexital 400mg Tablet safe for people with heart problems?

Does Flexital 400mg Tablet increase the risk of bleeding?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

References

User feedback

Patients taking Flexital 400mg Tablet

What are you using Flexital Tablet for?

How much was the improvement?

What were the side-effects while using Flexital 400mg Tablet?

How do you take Flexital Tablet?

Please rate Flexital 400mg Tablet on price

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests