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Oxyphenbutazone is used in the treatment of osteoarthritis, gout, rheumatoid arthritis and muscular pain.

How it works

Oxyphenbutazone belongs to a class of drugs called non-steroidal anti-inflammatory (NSAIDs). It acts by blocking the action of chemical known as prostaglandins, thereby helping in reducing pain, fever, or any anti-inflammatory effects.

Common side effects

Nausea, Acute toxicity, Gastritis, Gastrointestinal bleeding, Decreased white blood cell count, Rash, Stomach upset, Abdominal cramp, Bloating


Expert advice

• Exercise caution if you are a hypertensive patient.
• Tell your doctor if you are taking any anticoagulants and oral hypoglycemic agents as oxyphenbutazone may worsen the side effects.
• Do not drive or operate machinery after taking oxyphenbutazone as it may cause dizziness and movement disorder.
• Tell your doctor if you are pregnant or breast-feeding or planning a pregnancy.
• Should not be given to patients allergic to oxyphenbutazone or any of its ingredients.
• Should not be given to patients having active peptic ulcers due to increased chances of bleeding.
• Should not be given to patients having moderate to severe liver disease.

Content on this page was last updated on 21 November, 2016, by Dr. Varun Gupta (MD Pharmacology)