Evermil 5 Tablet

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 22 Apr 2026 | 05:28 PM (IST)

Evermil 5 Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.

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Evermil 5 Tablet

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Rolimus 5 Tablet

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Everolimus (5mg)

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General Information

Contains

Everolimus (5mg)

Marketer

Glenmark Pharmaceuticals Ltd

Storage

Store below 25°C

The content is shown in English

Product introduction

Evermil 5 Tablet must be taken in the dose and duration as per the prescription. It can be taken with or without food, but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.

The common side effects of this medicine include infection, fever, cough, fatigue, diarrhea, and upper respiratory infection. If any of the side effects persist or bother you, consult a doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough, or fever, or need to receive any vaccination after taking this medication.

Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform their doctor before the initiation of this treatment. During the treatment, your doctor may advise you to undergo some laboratory tests to determine the effects of the medicine on the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.

Uses of Evermil Tablet

Benefits of Evermil Tablet

Prevention of organ rejection in transplant patients
Evermil 5 Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.

Side effects of Evermil Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Evermil

Pneumonitis
Hypercholesterolemia (high cholesterol)
Increased aspartate aminotransferase
Decreased white blood cell count (lymphocytes)
Lymphopenia
Increased alanine aminotransferase
Increased triglyceride level in blood
Joint pain
Pleural effusion
Pulmonary edema
Stomatitis (Inflammation of the mouth)
Anemia (low number of red blood cells)
Decreased potassium level in blood
Weight loss
Taste change
Rash
Diarrhea
Infection
Breathlessness
Fatigue
Low blood platelets
Increased glucose level in blood
Decreased appetite

How to use Evermil Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Evermil 5 Tablet may be taken with or without food.

How Evermil Tablet works

Evermil 5 Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.

All substitutes for Evermil 5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Evermil 5 Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
Evermil 5 Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Evermil 5 Tablet increases your risk of getting an infection.
While you are taking Evermil 5 Tablet do not take any vaccinations without talking to your doctor first.
If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Evermil 5 Tablet.
Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Evermil 5 Tablet.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Evermil 5 Tablet. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Evermil 5 Tablet is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.

Breast feeding

CONSULT YOUR DOCTOR

Evermil 5 Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Evermil 5 Tablet may decrease alertness, affect your vision, or make you feel sleepy and dizzy. Do not drive if these symptoms occur.
As fatigue is a common side effect with Evermil 5 Tablet and this may affect your ability to drive

Kidney

SAFE IF PRESCRIBED

Evermil 5 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Evermil 5 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Evermil 5 Tablet is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Evermil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while undergoing treatment with Everolimus or for up to 6 months after stopping Everolimus.

Life-threatening

Natalizumab (Injection Route)

Do not consume Natalizumab with Everolimus.

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Cholera Vaccine (Inactivated) should not be used while undergoing treatment with Everolimus or for up to 6 months after stopping Everolimus.

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Purified Vi Polysaccharide Typhoid Vaccine should not be used while undergoing treatment with Everolimus or for up to 6 months after stopping Everolimus.

Severe

Temsirolimus (Injection Route)

Concurrent use should be avoided.

Frequently asked questions

Is any monitoring required while taking Evermil 5 Tablet?

Regular monitoring is required while you are on Evermil 5 Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Evermil 5 Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.

What should I avoid while taking Evermil 5 Tablet?

You should avoid grapefruit or grapefruit juice while taking Evermil 5 Tablet. This is because taking them together may increase the levels of Evermil 5 Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.

What is the most important information I need to know about Evermil 5 Tablet?

Evermil 5 Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.

Is Evermil 5 Tablet a chemotherapy?

Evermil 5 Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.

How is Evermil 5 Tablet administered?

Usually, Evermil 5 Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Evermil 5 Tablet should be swallowed whole with water and should not be crushed or chewed.

How long can you take Evermil 5 Tablet?

There is no definite duration of treatment with Evermil 5 Tablet. Evermil 5 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.

How will I know that Evermil 5 Tablet is shrinking my brain tumor?

The effect of Evermil 5 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.

Is Evermil 5 Tablet cytotoxic?

Yes, Evermil 5 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).

Is Evermil 5 Tablet a chemotherapy?

How is Evermil 5 Tablet administered?

How long can you take Evermil 5 Tablet?

There is no definite duration of treatment with Evermil 5 Tablet. Evermil 5 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.

Is any monitoring required while taking Evermil 5 Tablet?

How will I know that Evermil 5 Tablet is shrinking my brain tumor?

The effect of Evermil 5 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.

What should I avoid while taking Evermil 5 Tablet?

What is the most important information I need to know about Evermil 5 Tablet?

Is Evermil 5 Tablet cytotoxic?

Yes, Evermil 5 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).

Fact Box

Chemical Class

Macrolide lactams

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Mammalian Target of Rapamycin (mTOR) Kinase Inhibitors

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

Complete Blood Count

References

Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018]. [Accessed 22 Jan. 2019] (online) Available from:
CiplaMed. Tacrolimus [Prescribing Information]. [Last Updated: 17 May 2021]. [Accessed 20 Feb. 2024] (online) Available from:
Everolimus [Prescribing Information]. Berkeley Heights: Hikma Pharmaceuticals USA Inc.; 2023. [Accessed 20 Feb. 2024] (online) Available from:

User feedback

What are you using Evermil Tablet for?

Kidney cancer

50%

Breast cancer

50%

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Evermil 5 Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Evermil Tablet

Benefits of Evermil Tablet

Side effects of Evermil Tablet

How to use Evermil Tablet

How Evermil Tablet works

All substitutes for Evermil 5 Tablet

Volantis 5mg Tablet

Rolimus 5 Tablet

Evelimus 5mg Tablet

Afinitor 5mg Tablet

Torinat 5mg Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Natalizumab (Injection Route)

Cholera Vaccine (Inactivated) (Oral Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Temsirolimus (Injection Route)

Frequently asked questions

Is any monitoring required while taking Evermil 5 Tablet?

What should I avoid while taking Evermil 5 Tablet?

What is the most important information I need to know about Evermil 5 Tablet?

Is Evermil 5 Tablet a chemotherapy?

How is Evermil 5 Tablet administered?

How long can you take Evermil 5 Tablet?

How will I know that Evermil 5 Tablet is shrinking my brain tumor?

Is Evermil 5 Tablet cytotoxic?

Is Evermil 5 Tablet a chemotherapy?

How is Evermil 5 Tablet administered?

How long can you take Evermil 5 Tablet?

Is any monitoring required while taking Evermil 5 Tablet?

How will I know that Evermil 5 Tablet is shrinking my brain tumor?

What should I avoid while taking Evermil 5 Tablet?

What is the most important information I need to know about Evermil 5 Tablet?

Is Evermil 5 Tablet cytotoxic?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Carcino Embryonic Antigen

Complete Blood Count

References

User feedback

What are you using Evermil Tablet for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests