Evermil 5 Tablet
Prescription Required
Product introduction
Evermil 5 Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.
Evermil 5 Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.
The common side effects of this medicine include infection, fever, cough, fatigue, diarrhea, and upper respiratory infection. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.
Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.
Uses of Evermil Tablet
Benefits of Evermil Tablet
In Prevention of organ rejection in transplant patients
Evermil 5 Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Side effects of Evermil Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Evermil
- Decreased appetite
- Increased glucose level in blood
- Pneumonitis
- Hypercholesterolemia (high cholesterol)
- Increased aspartate aminotransferase
- Decreased white blood cell count (lymphocytes)
- Lymphopenia
- Increased alanine aminotransferase
- Increased triglyceride level in blood
- Joint pain
- Pleural effusion
- Pulmonary edema
- Rash
- Diarrhea
- Infection
- Breathlessness
- Stomatitis (Inflammation of the mouth)
- Fatigue
- Anemia (low number of red blood cells)
- Low blood platelets
- Decreased potassium level in blood
- Weight loss
- Taste change
How to use Evermil Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Evermil 5 Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Evermil Tablet works
Evermil 5 Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Evermil 5 Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Evermil 5 Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Evermil 5 Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Evermil 5 Tablet may cause side effects which could affect your ability to drive.
As fatigue is a common side effect with Evermil 5 Tablet and this may affect your ability to drive
As fatigue is a common side effect with Evermil 5 Tablet and this may affect your ability to drive
Kidney
SAFE IF PRESCRIBED
Evermil 5 Tablet is safe to use in patients with kidney disease. No dose adjustment of Evermil 5 Tablet is recommended.
Liver
CAUTION
Evermil 5 Tablet should be used with caution in patients with liver disease. Dose adjustment of Evermil 5 Tablet may be needed. Please consult your doctor.
Use of Evermil 5 Tablet is not recommended in patients with severe liver disease.
Use of Evermil 5 Tablet is not recommended in patients with severe liver disease.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Evermil 5 Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
- Evermil 5 Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
- Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Evermil 5 Tablet increases your risk of getting an infection.
- While you are taking Evermil 5 Tablet do not take any vaccinations without talking to your doctor first.
- If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Evermil 5 Tablet.
- Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Evermil 5 Tablet.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- mTOR inhibitors
Interaction with drugs
Taking Evermil with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while unde
Concurrent use may increase the risk of certain brain infections.
Do not consume Natalizumab with Everolimus.
Concurrent use may increase the risk of kidney damage.
If concurrent use is essential, your doctor may monitor your kidney function and Everolimus levels closely and adjust the do
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Cholera Vaccine (Inactivated) should not be used while undergoing treatment with Everoli
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Purified Vi Polysaccharide Typhoid Vaccine should not be used while undergoing treatment
Patient concerns
User feedback
What are you using Evermil Tablet for?
Kidney cancer
50%
Breast cancer
50%
FAQs
Is any monitoring required while taking Evermil 5 Tablet?
Regular monitoring is required while you are on Evermil 5 Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Evermil 5 Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
What should I avoid while taking Evermil 5 Tablet?
You should avoid grapefruit or grapefruit juice while taking Evermil 5 Tablet. This is because taking them together may increase the levels of Evermil 5 Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
What is the most important information I need to know about Evermil 5 Tablet?
Evermil 5 Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Is Evermil 5 Tablet a chemotherapy?
Evermil 5 Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
How is Evermil 5 Tablet administered?
Usually, Evermil 5 Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Evermil 5 Tablet should be swallowed whole with water and should not be crushed or chewed.
How long can you take Evermil 5 Tablet?
There is no definite duration of treatment with Evermil 5 Tablet. Evermil 5 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
How will I know that Evermil 5 Tablet is shrinking my brain tumor?
The effect of Evermil 5 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Is Evermil 5 Tablet cytotoxic?
Yes, Evermil 5 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
Is Evermil 5 Tablet a chemotherapy?
Evermil 5 Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
How is Evermil 5 Tablet administered?
Usually, Evermil 5 Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Evermil 5 Tablet should be swallowed whole with water and should not be crushed or chewed.
How long can you take Evermil 5 Tablet?
There is no definite duration of treatment with Evermil 5 Tablet. Evermil 5 Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Is any monitoring required while taking Evermil 5 Tablet?
Regular monitoring is required while you are on Evermil 5 Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Evermil 5 Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
How will I know that Evermil 5 Tablet is shrinking my brain tumor?
The effect of Evermil 5 Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
What should I avoid while taking Evermil 5 Tablet?
You should avoid grapefruit or grapefruit juice while taking Evermil 5 Tablet. This is because taking them together may increase the levels of Evermil 5 Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
What is the most important information I need to know about Evermil 5 Tablet?
Evermil 5 Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Is Evermil 5 Tablet cytotoxic?
Yes, Evermil 5 Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
- Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
- Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018]. [Accessed 22 Jan. 2019] (online) Available from:
- CiplaMed. Tacrolimus [Prescribing Information]. [Last Updated: 17 May 2021]. [Accessed 20 Feb. 2024] (online) Available from:
- Everolimus [Prescribing Information]. Berkeley Heights: Hikma Pharmaceuticals USA Inc.; 2023. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.
Country of origin: India
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