Afinitor 5mg Tablet
Prescription Required
Product introduction
Afinitor 5mg Tablet is used for the prevention of organ rejection in transplant patients. It regulates the body’s immune response, so the body can accept the new organ. It is also used in combination with other medicines to treat cancers of breast, pancreas, lungs, and kidney.
Afinitor 5mg Tablet must be taken in a dose and duration as per the prescription. It can be taken with or without food but make sure to take it at about the same time every day. An overdose of this medicine may have serious side effects on the body.
The common side effects of this medicine include infection, fever, cough, fatigue, diarrhea, and upper respiratory infection. If any of the side effects persist or bother you, consult the doctor immediately. Inform the doctor immediately if you experience any allergic reactions (rash, shortness of breath, coughing, swelling, etc.). Always seek medical advice if you have increased thirst or increased frequency of urination, suffer from shortness of breath, cough or fever, or need to receive any vaccination after taking this medication.
Before taking this medicine, it is important to consult your doctor if you have any ongoing medication for any underlying disease. Pregnant and breastfeeding women must inform the doctor prior to the initiation of this treatment. During the treatment, your doctor may advise you for some laboratory tests to know the effects of the medicine in the body. It may affect male or female fertility, so consult the doctor if you are planning to have a child.
Uses of Afinitor Tablet
Benefits of Afinitor Tablet
In Prevention of organ rejection in transplant patients
Afinitor 5mg Tablet is used with other medications to prevent organ transplant rejection. Rejection usually happens due to attack by the immune system of the person receiving the transplanted organ on the transplant itself, in people who are receiving any organ transplants, like kidney, liver, heart etc. This medicine reduces the activity of a person's own immune system and prevents any such rejection.
Side effects of Afinitor Tablet
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Afinitor
- Decreased appetite
- Increased glucose level in blood
- Pneumonitis
- Hypercholesterolemia (high cholesterol)
- Increased aspartate aminotransferase
- Decreased white blood cell count (lymphocytes)
- Lymphopenia
- Increased alanine aminotransferase
- Increased triglyceride level in blood
- Joint pain
- Pleural effusion
- Pulmonary edema
- Rash
- Diarrhea
- Infection
- Breathlessness
- Stomatitis (Inflammation of the mouth)
- Fatigue
- Anemia (low number of red blood cells)
- Low blood platelets
- Decreased potassium level in blood
- Weight loss
- Taste change
How to use Afinitor Tablet
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Afinitor 5mg Tablet may be taken with or without food, but it is better to take it at a fixed time.
How Afinitor Tablet works
Afinitor 5mg Tablet suppresses the activity of body's immune system and prevents rejection of the transplanted organ.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Afinitor 5mg Tablet. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Afinitor 5mg Tablet is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breast feeding
CONSULT YOUR DOCTOR
Afinitor 5mg Tablet is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
Driving
UNSAFE
Afinitor 5mg Tablet may cause side effects which could affect your ability to drive.
As fatigue is a common side effect with Afinitor 5mg Tablet and this may affect your ability to drive
As fatigue is a common side effect with Afinitor 5mg Tablet and this may affect your ability to drive
Kidney
SAFE IF PRESCRIBED
Afinitor 5mg Tablet is safe to use in patients with kidney disease. No dose adjustment of Afinitor 5mg Tablet is recommended.
Liver
CAUTION
Afinitor 5mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Afinitor 5mg Tablet may be needed. Please consult your doctor.
Use of Afinitor 5mg Tablet is not recommended in patients with severe liver disease.
Use of Afinitor 5mg Tablet is not recommended in patients with severe liver disease.
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For informational purposes only. Consult a doctor before taking any medicines.
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Quick tips
- Afinitor 5mg Tablet is given for the treatment of certain cancers and to prevent organ transplant rejection.
- Afinitor 5mg Tablet may affect male or female fertility; consult your doctor if you are planning to have a child.
- Inform your doctor straight away if you think you are getting a sore throat or if you have a high temperature. This is because Afinitor 5mg Tablet increases your risk of getting an infection.
- While you are taking Afinitor 5mg Tablet do not take any vaccinations without talking to your doctor first.
- If you are having an operation or dental treatment, always tell the person carrying out the treatment that you are taking Afinitor 5mg Tablet.
- Do not drink grapefruit juice while you are taking this medicine. This is because a chemical in grapefruit juice can interfere with the action of Afinitor 5mg Tablet.
Fact Box
Chemical Class
Macrolide Lactams
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Immunosuppressant- mTOR inhibitors
Interaction with drugs
Taking Afinitor with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) should not be used while unde
Concurrent use may increase the risk of certain brain infections.
Do not consume Natalizumab with Everolimus.
Concurrent use may increase the risk of kidney damage.
If concurrent use is essential, your doctor may monitor your kidney function and Everolimus levels closely and adjust the do
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Cholera Vaccine (Inactivated) should not be used while undergoing treatment with Everoli
Concomitant use may cause a severe drop in blood pressure that may lead to a heart attack.
Purified Vi Polysaccharide Typhoid Vaccine should not be used while undergoing treatment
Patient concerns
User feedback
Patients taking Afinitor 5mg Tablet
Once A Day
100%
What are you using Afinitor Tablet for?
Others
57%
Breast cancer
43%
How much was the improvement?
Poor
100%
FAQs
Is any monitoring required while taking Afinitor 5mg Tablet?
Regular monitoring is required while you are on Afinitor 5mg Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Afinitor 5mg Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
What should I avoid while taking Afinitor 5mg Tablet?
You should avoid grapefruit or grapefruit juice while taking Afinitor 5mg Tablet. This is because taking them together may increase the levels of Afinitor 5mg Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
What is the most important information I need to know about Afinitor 5mg Tablet?
Afinitor 5mg Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Is Afinitor 5mg Tablet a chemotherapy?
Afinitor 5mg Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
How is Afinitor 5mg Tablet administered?
Usually, Afinitor 5mg Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Afinitor 5mg Tablet should be swallowed whole with water and should not be crushed or chewed.
How long can you take Afinitor 5mg Tablet?
There is no definite duration of treatment with Afinitor 5mg Tablet. Afinitor 5mg Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
How will I know that Afinitor 5mg Tablet is shrinking my brain tumor?
The effect of Afinitor 5mg Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
Is Afinitor 5mg Tablet cytotoxic?
Yes, Afinitor 5mg Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
Is Afinitor 5mg Tablet a chemotherapy?
Afinitor 5mg Tablet is an anticancer medicine. It belongs to kinase inhibitor class of medicines. It works by reducing the blood supply to the tumor, which slows down the growth and spread of cancer cells.
How is Afinitor 5mg Tablet administered?
Usually, Afinitor 5mg Tablet is taken once or twice daily. The medicine should always either be taken with food or always be taken without food. Afinitor 5mg Tablet should be swallowed whole with water and should not be crushed or chewed.
How long can you take Afinitor 5mg Tablet?
There is no definite duration of treatment with Afinitor 5mg Tablet. Afinitor 5mg Tablet is continued till clinical benefit is seen or unacceptable toxicity or side effects occur.
Is any monitoring required while taking Afinitor 5mg Tablet?
Regular monitoring is required while you are on Afinitor 5mg Tablet. The doctor will advise blood tests to see the counts of red blood cells, white blood cells, and platelets since the counts may decrease during treatment with Afinitor 5mg Tablet. Also, blood tests will be required to check your kidney function, liver function, blood glucose levels, and cholesterol levels.
How will I know that Afinitor 5mg Tablet is shrinking my brain tumor?
The effect of Afinitor 5mg Tablet in shrinking the size of tumor can only be checked by getting regular brain scans. It should be done as advised by your doctor and your treatment plan.
What should I avoid while taking Afinitor 5mg Tablet?
You should avoid grapefruit or grapefruit juice while taking Afinitor 5mg Tablet. This is because taking them together may increase the levels of Afinitor 5mg Tablet in your blood to harmful levels. Avoid the use of live vaccinations and any possible contact with individuals who have received live vaccinations.
What is the most important information I need to know about Afinitor 5mg Tablet?
Afinitor 5mg Tablet can cause serious side effects which include severe allergic reactions, angioedema, and kidney failure which can be severe and can lead to death. It is possible that you may develop an infection or problems related to lung such as breathing problems.
Is Afinitor 5mg Tablet cytotoxic?
Yes, Afinitor 5mg Tablet is cytotoxic against human cancer cells of breast, stomach, prostate, and kidneys (renal cell carcinoma).
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Krensky AM, Bennett WM, Vincenti F. Immunosuppressants, Tolerogens, and Immunostimulants. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. p. 1013.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 526.
- Everolimus. East Hanover, New Jersey: Novartis Pharmaceuticals Corporation; 2009 [revised Apr. 2018]. [Accessed 06 Apr. 2019] (online) Available from:
- Everolimus. Camberley, Surrey: Novartis Pharmaceuticals UK Ltd.; 2011 [revised 12 Jul 2018]. [Accessed 22 Jan. 2019] (online) Available from:
- CiplaMed. Tacrolimus [Prescribing Information]. [Last Updated: 17 May 2021]. [Accessed 20 Feb. 2024] (online) Available from:
- Everolimus [Prescribing Information]. Berkeley Heights: Hikma Pharmaceuticals USA Inc.; 2023. [Accessed 20 Feb. 2024] (online) Available from:
Marketer details
Name: Novartis India Ltd
Address: Sandoz House, Shiv Sagar Estate, Worli Mumbai -400 018, India
Country of origin: India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Afinitor 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
Expires on or after: March, 2025
A licensed vendor partner from your nearest location will deliver Afinitor 5mg Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
In case of any issues, contact us
Email ID: [email protected]Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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