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Espin 2.5 Tablet

Written By Dr. Syeda Aafia, MBA, BDS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 07 Apr 2026 | 02:54 PM (IST)
Espin 2.5 Tablet is a medicine used to treat high blood pressure (hypertension) and to prevent angina (heart-related chest pain) and stroke. It is a calcium channel blocker which helps to lower blood pressure and reduce the workload of the heart. This helps prevent heart attacks and strokes.
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Espin 2.5 Tablet
Espin 2.5 Tablet
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₹5.84 per tablet
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by Intas Pharmaceuticals Ltd
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Eslo 2.5 Tablet
Eslo 2.5 Tablet
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₹81

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₹1200
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by Zuventus Healthcare Ltd

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General Information

Contains

S-Amlodipine (2.5mg)

Salt Synonyms

Amlodipine

Marketer

Intas Pharmaceuticals Ltd

Storage

Store below 25°C
The content is shown in English
Espin 2.5 Tablet image
Espin 2.5 Tablet image
Espin 2.5 Tablet image
Espin 2.5 Tablet image
Espin 2.5 Tablet image
Espin 2.5 Tablet image

Product introduction

Espin 2.5 Tablet may be prescribed alone or along with other medicines. The dose depends on what you are taking it for and the severity of your condition. You can take it at any time of the day with or without food, but it is best to take it at the same time each day. Keep taking it for as long as advised by your doctor. Even if you feel well, do not stop this medicine on your own because high blood pressure often has no symptoms. If you stop taking it, your condition may get worse.


Keeping active with regular exercise, reducing your weight, and eating a healthy diet will also help control your blood pressure. Follow your doctor's advice while taking this medicine.


Common side effects of Espin 2.5 Tablet include oedema, drowsiness, dizziness, headache, visual disturbance, and palpitations. Consult your doctor if any of these bother you or do not go away. It has a lower chance of causing swelling in the feet as compared to some other medicines belonging to this group.


Before taking it, let your doctor know if you have any liver, heart, or kidney problems. Pregnant or breastfeeding women should also consult their doctor for advice before taking this medicine. Let your doctor know about any other medicines you are taking, especially those used to treat high blood pressure or heart conditions. This will help to make sure that you are safe. 


Limit your alcohol intake while taking this medicine because it can significantly decrease your blood pressure levels and make you feel dizzy or lightheaded. You should have your blood pressure checked regularly to make sure that this medicine is working properly.

Uses of Espin Tablet

Benefits of Espin Tablet

Angina (heart-related chest pain)
Espin 2.5 Tablet helps prevent chest pain (angina) by improving blood flow to the heart. It relaxes and widens the blood vessels, making it easier for the heart to get enough oxygen, especially during physical activity or stress. This helps reduce the frequency and severity of chest pain and allows you to stay more active without discomfort.
Treatment of Hypertension (high blood pressure)
Espin 2.5 Tablet is a calcium channel blocker. It works by relaxing the blood vessels so that blood can flow more easily around your body. This lowers your blood pressure and reduces your risk of having a stroke, a heart attack, or kidney problems in the future. You do not usually feel any direct benefit from taking this medicine, but it works in the long term to keep you well. Take regularly, as prescribed for this medicine to be most effective, even if you feel better.
Prevention of Stroke
Espin 2.5 Tablet reduces the risk of future strokes. It helps lower your blood pressure and make it easier for your heart to pump blood around your body. This reduces the chances of you having a stroke. Take it as advised by the doctor to get the maximum benefit.

Side effects of Espin Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Espin
  • Sleepiness
  • Visual disturbance
  • Dyspepsia
  • Change in bowel habits
  • Angioedema (swelling of deeper layers of skin)
  • Ankle swelling
  • Dizziness
  • Fatigue
  • Flushing (sense of warmth in the face, ears, neck and trunk)
  • Headache
  • Palpitations
  • Abdominal pain
  • Muscle cramp
  • Nausea
  • Breathlessness

How to use Espin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Espin 2.5 Tablet may be taken with or without food.

How Espin Tablet works

Espin 2.5 Tablet is a calcium channel blocker. In high blood pressure, it normalizes the blood pressure by relaxing the blood vessels to reduce the pressure on them, thereby improving the blood flow in the body. The enhanced blood flow in the body further relaxes the heart muscles by reducing the workload on the heart. It also improves the oxygen flow in the body, thereby, preventing any heart-related chest pain.

All substitutes for Espin 2.5 Tablet

For information purposes only. Consult a doctor before taking any medicine.

Eslo 2.5 Tablet

by Zuventus Healthcare Ltd
₹6.35/tablet
8% cheaper
<h3 class=bodySemiBold>Eslo 2.5 Tablet</h3>

Asomex 2.5 Tablet

by Emcure Pharmaceuticals Ltd
₹6.52/tablet
5% cheaper
<h3 class=bodySemiBold>Asomex 2.5 Tablet</h3>

eSAM 2.5 Tablet

by Torrent Pharmaceuticals Ltd
₹8.61/tablet
25% costlier
<h3 class=bodySemiBold>eSAM 2.5 Tablet</h3>

S-Amlosafe 2.5 Tablet

by Aristo Pharmaceuticals Pvt Ltd
₹4.19/tablet
39% cheaper
<h3 class=bodySemiBold>S-Amlosafe 2.5 Tablet</h3>

S-Amcard 2.5 Tablet

by Systopic Laboratories Pvt Ltd
₹1.6/tablet
77% cheaper
<h3 class=bodySemiBold>S-Amcard 2.5 Tablet</h3>

Quick tips

  • Take it at the same time every day to help you remember to take it.
  • A sudden drop in your blood pressure may occur, especially when you first start taking Espin 2.5 Tablet. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down.
  • It can cause ankle or foot swelling. To reduce the swelling, raise your legs while you are sitting down. Talk to your doctor if it does not go away.
  • It may cause dizziness. Do not drive or perform any activity that requires mental focus until you know how Espin 2.5 Tablet affects you. 
  • Inform your doctor if you are pregnant, planning a pregnancy or breastfeeding. 

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Espin 2.5 Tablet. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Espin 2.5 Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CONSULT YOUR DOCTOR
Information regarding the use of Espin 2.5 Tablet during breastfeeding is not available. Please consult your doctor.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Espin 2.5 Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

SAFE IF PRESCRIBED
Espin 2.5 Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.
Liver

Liver

CAUTION
Espin 2.5 Tablet should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Espin 2.5 Tablet starts working on the day it is taken. However, it may take weeks to see the full effect. You should continue taking the medicine even if you feel better or if you do not notice any considerable difference. Consult your doctor if you have any concerns or you feel worse after taking the medicine.
Espin 2.5 Tablet may cause itching in some patients, though it is an uncommon side effect. However, if you experience severe itching contact your doctor.
No, there is no evidence that Espin 2.5 Tablet causes deterioration of kidney problems. Espin 2.5 Tablet can be used in normal doses in patients with kidney problems. In fact, its blood pressure-lowering effect helps to prevent injury to the kidneys due to hypertension.
Espin 2.5 Tablet can be taken anytime in the morning or evening, usually prescribed once daily. Take the medicine as advised by the doctor. It is advised to take it at the same time each day so that you remember to take it and consistent levels of medicine are maintained in the body.
You should keep on taking Espin 2.5 Tablet for as long as your doctor has recommended you to take it. You may need to take it lifelong. Do not stop taking it, even if you feel well or your blood pressure is well controlled. If you stop taking Espin 2.5 Tablet, your blood pressure may increase again and your condition may worsen.
No, Espin 2.5 Tablet is not a beta-blocker. It belongs to a class of medicines known as calcium channel blockers. It lowers blood pressure by relaxing the blood vessels so that blood can easily flow through the blood vessels.
Espin 2.5 Tablet may cause some serious side effects such as liver problems (yellowing of skin, nausea, vomiting, and loss of appetite), pancreatitis (severe stomach pain, nausea, and vomiting), and recurrent chest pain which may be indicative of a heart attack. However, these side effects are rarely seen. Remember that your doctor has prescribed this medicine to you because the benefit to you is greater than the risk of any potential side effects. Follow your doctor's advice.
Consult your doctor first before starting any new prescription or non-prescription medicines or supplements. Take low sodium and low-fat diet, and adhere to the lifestyle changes as advised by your doctor. Avoid eating grapefruit (chakotra) or drinking grapefruit juice while taking Espin 2.5 Tablet. Stop smoking and taking alcohol as this helps to lower your blood pressure and prevents heart problems.
Espin 2.5 Tablet can cause ankle or foot swelling. To reduce swelling raise your legs while you are sitting down. Talk to your doctor if it does not go away.

Fact Box

Chemical Class

Dihydropyridine carboxylic acid derivative

Habit Forming

No

Therapeutic Class

CARDIAC

Action Class

Calcium Channel Blockers- Dihydropyridines (DHP)

Related lab tests

Activated Partial Thromboplastin Time

Complete Blood Count

Kidney Function Test

Prothrombin Time

References

  1. Central Drugs Standard Control Organisation (CDSCO). [Accessed 19 Mar. 2019] (online) Available from:
  2. Galappatthy P, Waniganayake YC, Sabeer MI, et al. Leg edema with (S)-amlodipine vs conventional amlodipine given in triple therapy for hypertension: A randomized double blind controlled clinical trial. BMC Cardiovasc Disord. 2016;16:168. [Accessed 31 Jul. 2020]. (online) Available from:
  3. Şen S, Demir M, Yiğit Z, et al. Efficacy and Safety of S-Amlodipine 2.5 and 5 mg/d in Hypertensive Patients Who Were Treatment-Naive or Previously Received Antihypertensive Monotherapy. J Cardiovasc Pharmacol Ther. 2018;23(4):318-328. [Accessed 31 Jul. 2020]. (online) Available from:
  4. S-Amlodipine Besilate [Patient Information Leaflet]. Bari-Brahamana, J&K: Emcure Pharmaceuticals Ltd.; 2024. [Accessed 07 Jul. 2025] (online) Available from:
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User feedback

Once A Day
100%
Hypertension (high blood pressure)
87%
Others
13%
Excellent
43%
Average
33%
Poor
24%
No Side Effect
100%
With food
100%
Not Expensive
42%
Average
33%
Expensive
25%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Intas Pharmaceuticals Ltd
Address: Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Espin 2.5 Tablet. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

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Most medicines cannot be sold without a valid prescription, as per the Drugs and Cosmetics Act, 1940 and Rules, 1945
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