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Duphalac Oral Solution Lemon

Lactulose (3.335gm/5ml)
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Duphalac Oral Solution Lemon is a type of sugar used to treat constipation. It is known as a laxative and makes your stool easier to pass by drawing water into your bowel. It is also used to treat hepatic encephalopathy (a liver disease causing confusion, tremor, decreased level of consciousness).

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 04 Feb 2026 | 05:00 PM (IST)
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150 ml Oral Solution
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General Information

The content is shown in English
Duphalac Oral Solution Lemon image
Duphalac Oral Solution Lemon image
Duphalac Oral Solution Lemon image

Product introduction

Duphalac Oral Solution Lemon can be taken with or without food. You should take this medicine as advised by your doctor. Use this medicine regularly to get the maximum benefit and try to take it at the same time(s) each day. Your dose may go up or down depending on how well it is working. Do not take more than you are advised to and, if you miss a dose, do not take an extra one to make up for it. This medicine takes at least 48 hours to work. Talk to your doctor if you are still constipated after 3 days.

The most common side effects are nausea and vomiting. These are usually mild and go away after a couple of days. Occasionally people develop serious side effects including severe diarrhea and electrolyte imbalance. Talk to your doctor straight away if you notice any of these.

Before taking this medicine, you should tell your doctor if you have diabetes or if you are unable to digest milk sugar (lactose intolerant). If you use this medicine over a long period of time, your doctor may want you to have occasional blood tests to check the mineral levels (e.g. potassium and sodium). Do not take other laxative medicines while taking this medicine and check with your doctor if you are pregnant or breastfeeding.

Uses of Duphalac Oral Solution

Benefits of Duphalac Oral Solution

Constipation
Constipation occurs when bowel movements become less frequent and stools are hard to pass. Duphalac Oral Solution Lemon helps soften the stool and increases bowel movement frequency by drawing water into the intestines. This provides gentle and effective relief from constipation and improves digestive comfort.
Treatment of Hepatic encephalopathy
Hepatic encephalopathy is a liver-related condition that affects brain function due to the buildup of toxins in the blood. Duphalac Oral Solution Lemon helps remove these toxins, especially ammonia, through bowel movements. This helps improve mental clarity, reduces confusion, and supports better liver health and overall well-being.

Side effects of Duphalac Oral Solution

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Duphalac
  • Nausea
  • Flatulence
  • Abdominal pain
  • Diarrhea
  • Vomiting

How to use Duphalac Oral Solution

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Duphalac Oral Solution Lemon may be taken with or without food.

How Duphalac Oral Solution works

Duphalac Oral Solution Lemon works by drawing water into the intestine through osmosis, which makes the stool soft and easier to pass.

All substitutes for Duphalac Oral Solution Lemon

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Duphalac Oral Solution Lemon should preferably be taken at bedtime as it requires 6 to 8 hours to show effect.
  • It is usually taken once a day as needed for up to 2 weeks. Take it exactly as prescribed by the doctor.
  • Take it atleast 2 hours after taking other medicines, as it may interfere with the absorption of other medicines.
  • Inform your doctor if you have a history of stomach disorders such as appendicitis or a blockage in your bowel.
  • Some healthy tips to prevent constipation from happening:
    • Eat more fiber in your diet. Recommended daily intake is 20-35g
    • Drink 8-10 glasses of water per day
    • Exercise regularly at least 3 times per week
    • Do not hold in stool as that can worsen bowel issues

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Duphalac Oral Solution Lemon. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
The safety of Duphalac Oral Solution Lemon during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.
Breast feeding

Breast feeding

CAUTION
Duphalac Oral Solution Lemon should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.
Driving

Driving

SAFE
Duphalac Oral Solution Lemon does not usually affect your ability to drive.
Kidney

Kidney

CONSULT YOUR DOCTOR
There is limited data available on the use of Duphalac Oral Solution Lemon in patients with kidney disease. Please consult your doctor.
Liver

Liver

SAFE IF PRESCRIBED
Duphalac Oral Solution Lemon is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Duphalac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Moderate

Acenocoumarol (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine). Lactulose may increase the effect of Acenocoumarol.
Moderate

Warfarin (Oral Route)

Inform your doctor if you notice any signs of bleeding (bruising, bleeding gums, blood in stool/vomit/urine). Lactulose may increase the effect of Warfarin.
Mild

Mesalazine (Oral Route)

Talk to your doctor if you notice any unusual symptoms.Doctor may monitor your blood sugar level. Lactulose may reduce blood levels and efficacy of the active form of Mesalazine.

Frequently asked questions

You should take the prescribed amount in the measuring cup or spoon that is provided with the medicine. You can take it with water or fruit juice if you find it very sweet. Drink plenty of water for better results. Swallow it as soon as you keep it in mouth to prevent tooth decay which can occur if you take it for a longer time.
It takes about 2-3 days to see the benefits of the treatment. Talk to your doctor if you feel constipated even after 3 days of taking Duphalac Oral Solution Lemon.
Duphalac Oral Solution Lemon is used to treat constipation which is presented as infrequent bowel movements, hard and dry stools. It is also used in patients with hepatic encephalopathy which is a serious liver problem causing confusion, tremors and decreased level of consciousness.
Yes, Duphalac Oral Solution Lemon is a laxative which softens the stools by pulling in water from the body to the large intestine. It is also used to reduce the amount of ammonia in the blood of patients with liver disease.
Duphalac Oral Solution Lemon very commonly causes diarrhea, flatulence, nausea, vomiting and abdominal pain. Diarrhea and abdominal pain occur due to a high dose. In such cases, the dose should be reduced. Flatulence may occur during the first few days of treatment and may disappear after sometime. This medicine may also cause electrolyte imbalance. However, this is an uncommon side effect.
You should take Duphalac Oral Solution Lemon for as long as advised by your doctor. You may also take it for as long as constipation lasts, which may be up to a week. For hepatic encephalopathy, the treatment may be longer, even several months.
Duphalac Oral Solution Lemon should not be given to patients who are allergic to it or are intolerant to lactose (cannot process lactose). It should also be avoided in patients having galactosemia, a rare health problem where the body cannot process galactose.
Usually, one laxative is sufficient to relieve constipation. In case you need more, your doctor may advise you to take one more laxative along with Duphalac Oral Solution Lemon. The risk of side effects is more with two laxatives.

Fact Box

Chemical Class

O-glycosyl compounds

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Osmotic Laxatives / Purgatives

References

  1. Sharkey KA, Wallace JL. Treatment of Disorders of Bowel Motility and Water Flux; Anti-Emetics; Agents Used in Biliary and Pancreatic Disease. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1332.
  2. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1079.
  3. Lactulose. Maidenhead, Berkshire: Intrapharm Laboratories Limited; 2015 [revised 12 Jan. 2017]. [Accessed 27 Mar. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
  5. Lactulose. Greenville, SC: PAI Pharma; 2025 [Accessed 04 Feb. 2026] (online). Available from:
  6. Lactulose. Olst, The Netherlands: Abbott Biologicals B.V.; 2022 [Accessed 04 Feb. 2026] (online). Available from:
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User feedback

Once A Day
75%
Twice A Day
17%
Thrice A Day
8%
Constipation
95%
Others
5%
Average
38%
Poor
33%
Excellent
29%
No Side Effect
76%
Vomiting
6%
Stomach pain
6%
Flatulence
4%
Nausea
4%
With food
63%
With or without food
27%
Empty stomach
10%
Expensive
50%
Average
35%
Not Expensive
16%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Manufacturer details

Name: A)Abbott Ltd
Address: A)L-18/19, Verna Industrial Estate, Verna, Salcette, Goa - 403 7

Marketer details

Name: Abbott
Address: 16th Floor, Godrej BKC, Plot – C, “G” Block, Bandra-Kurla Complex, Bandra (East), Mumbai – 400 051, India

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Duphalac Oral Solution Lemon. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India
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