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Doriglen Injection

Doripenem (500mg)

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Doriglen Injection is an antibiotic medicine that is used to treat severe infections of the skin, lungs, stomach, urinary tract, blood, and brain (e.g., meningitis). It works by killing the bacteria that cause these infections.

Written By Dr. Swati Mishra, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 30 Jan 2026 | 03:40 PM (IST)

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General Information

Contains

Doripenem (500mg)

Marketer

Glenmark Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Doriglen Injection is commonly used to treat seriously ill patients admitted to the hospital. This medicine is given by drip or by direct injection into a vein, under the supervision of a healthcare professional. The dose will depend on what type of infection you have, where it is in the body, and how serious it is. You should keep on taking the injection for as long as you have been prescribed, even if your symptoms quickly improve. If you stop taking it too early the infection may return or worsen.

Some people may develop side effects like headache, nausea, diarrhea, and rash. These side effects are usually temporary and go away as your body adjusts to the medicine. Consult your doctor if these side effects bother you or persist.

Before starting treatment with this medicine, you should tell your doctor if you have epilepsy, liver, or kidney problems or if you are allergic to any antibiotic. While using it, you may be advised blood tests to monitor your blood cell counts and kidney function. This medicine is generally regarded as safe to use in pregnancy and breastfeeding if prescribed by your doctor.

Uses of Doriglen Injection

Severe bacterial infections

Benefits of Doriglen Injection

Severe bacterial infections
Doriglen Injection works by killing bacteria which can cause serious infections. It is a versatile medicine used to treat many different types of bacterial infections such as infections of the brain (meningitis), lungs (pneumonia), abdomen, urinary tract, skin, blood, and heart. This medicine is usually given as an injection by a doctor or nurse.

Doriglen Injection usually makes you feel better very quickly but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

Side effects of Doriglen Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Doriglen

Headache
Nausea
Rash
Diarrhea
Inflammation of vein

How to use Doriglen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Doriglen Injection works

Doriglen Injection is an antibiotic. It kills bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive.

All substitutes for Doriglen Injection

For information purposes only. Consult a doctor before taking any medicine.

Doriray 500mg Injection

by Mylan Pharmaceuticals Pvt Ltd - A Viatris Company

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Dorilon 500mg Injection

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₹4405.31/injection

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Quick tips

Doriglen Injection is an antibiotic that's usually only given in the hospital for serious infections.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes. In severe cases, it may be given slowly for 3 to 4 hours by intravenous infusion.
Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.
Doriglen Injection is an antibiotic that's usually only given in the hospital for serious infections.
It is given by a drip into a vein (intravenous infusion) over 20 to 60 minutes.
Inform your doctor if you are allergic to penicillin or if you are taking any seizure medication before starting treatment with this medication.
Diarrhea may occur as a side effect. Inform your doctor if you develop severe stomach pain or if you find blood in your stools.
Your doctor may monitor your liver and kidney function while you are having treatment with this medication.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Doriglen Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Doriglen Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CAUTION

Doriglen Injection should be used with caution during breastfeeding. Breastfeeding should be held until the treatment of the mother is completed and the drug is eliminated from the body.

Driving

SAFE

Doriglen Injection does not usually affect your ability to drive.

Kidney

CAUTION

Doriglen Injection should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.

Liver

SAFE IF PRESCRIBED

Doriglen Injection is safe to use in patients with liver disease. No dose adjustment is recommended.

Interaction with drugs

Taking Doriglen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not consume Cholera Vaccine (Inactivated) two weeks before and at least 10 days after consuming Doripenem. Please consult your doctor. Doripenem may reduce the efficacy of Cholera Vaccine (Inactivated).

Moderate

Probenecid (Oral Route)

Do not consume Doripenem with Probenecid. Probenecid may raise blood levels of Doripenem.

Moderate

Phenindione (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Phenindione accordingly.

Moderate

Warfarin (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Warfarin accordingly.

Mild

Acenocoumarol (Oral Route)

Your doctor may monitor your blood coagulation status and adjust the dose of Acenocoumarol accordingly.

Frequently asked questions

What is Doriglen Injection used for?

Doriglen Injection is used to fight bacterial infections and prevent bacteria from growing. It acts by interfering with the bacterial protein synthesis which helps to treat the infection. Doriglen Injection is also helpful in the treatment of bacterial infections of the bladder, kidney and other parts of the urinary tract.

Is Doriglen Injection available over-the-counter?

No, Doriglen Injection, just like other antibiotics, requires a valid prescription by a doctor to buy it. Therefore, it is advisable to take Doriglen Injection only if prescribed by a doctor.

How is Doriglen Injection administered?

Doriglen Injection should be administered under the supervision of a trained healthcare professional or a doctor only and should not be self-administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Doriglen Injection.

Does Doriglen Injection cure flu?

No, antibiotics such as Doriglen Injection will not work for flu or other viral infections. Using antibiotics when they are not needed may increase your risk of getting infection later, that resists antibiotic treatment. Consult your doctor if you have any doubts.

What happens if I take too much of Doriglen Injection?

If you have mistakenly taken too much of Doriglen Injection, you may experience symptoms such as stomach ache, nausea and vomiting. You should consult your doctor immediately or rush to the emergency room in any nearby hospital if you have taken an overdose of Doriglen Injection.

Should I avoid some medicines while taking Doriglen Injection?

Yes. There are some medicines that may reduce the effect of Doriglen Injection, interact with Doriglen Injection or cause serious side-effects when given at the same time. These medicines include Sodium Valproate, Ethinyl Estradiol and Live cholera vaccine. So, always inform and check with your doctor before taking Doriglen Injection with other medications.

How to store Doriglen Injection?

Doriglen Injection should be stored at around the room temperature (not more than 25°C) away from heat and sunlight. Do not freeze it and always keep it out of the reach and sight of the children.

Fact Box

Chemical Class

Thienamycins

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Carbapenems

Related lab tests

Complete Blood Count

References

Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 427.
Doripenem. Japan: Shionogi & Co. Ltd.; 2007. [Accessed 29 Mar. 2019] (online) Available from:
Central Drugs Standard Control Organisation (CDSCO). [Accessed 28 Mar. 2019] (online) Available from:

User feedback

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Severe bacterial infections

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glenmark Pharmaceuticals Ltd
Address: Glenmark Pharmaceuticals Limited, B/2, Mahalaxmi Chambers, 22, Bhulabhai Desai Road, Mumbai – 400 026.

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Doriglen Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Doriglen Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Doriglen Injection

Benefits of Doriglen Injection

Side effects of Doriglen Injection

How to use Doriglen Injection

How Doriglen Injection works

All substitutes for Doriglen Injection

Doriray 500mg Injection

Dorilon 500mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Probenecid (Oral Route)

Phenindione (Oral Route)

Warfarin (Oral Route)

Acenocoumarol (Oral Route)

Frequently asked questions

What is Doriglen Injection used for?

Is Doriglen Injection available over-the-counter?

How is Doriglen Injection administered?

Does Doriglen Injection cure flu?

What happens if I take too much of Doriglen Injection?

Should I avoid some medicines while taking Doriglen Injection?

How to store Doriglen Injection?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Complete Blood Count

References

User feedback

What are you using Doriglen Injection for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests