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Domsettler Suspension

Written By Dr. Anuj Saini, MMST, MBBS
Reviewed By Dr. Rajeev Sharma, MBA, MBBS
Last updated on 14 Apr 2026 | 04:20 PM (IST)
Domsettler Suspension helps treat indigestion, gastroesophageal reflux disease, nausea, and vomiting in children. It increases the movement of food through the stomach and intestines, thereby relieving bloating, fullness, and gastric discomfort.
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General Information

The content is shown in English
Domsettler Suspension image
Domsettler Suspension image

Your child’s medicine at a glance

Domsettler Suspension is best given half an hour before each meal. If given after meals, it will still work but the absorption of the medicine may get affected. For young babies, the doctor may prescribe giving it four times each day. Wait for at least 4 hours between doses and give each dose just before a milk feed. The doses usually vary depending upon your child’s condition, body weight, and age. Never exceed the prescribed duration without consulting the doctor. If your child vomits within 30 minutes of the intake, repeat the same dose once your child calms down, but do not double dose if it is time for the next dose.

This medicine may cause some minor and temporary side effects such as dry mouth, headache, drowsiness, stomach cramps, and diarrhea. Usually, these episodes subside once your child’s body adapts to the medicine. However, if these side effects persist or become bothersome for your child, report to the doctor without any delay.

Your child’s doctor should be aware if your child has had any previous episodes of allergy, heart problem, a blood disorder, birth defects, airway obstruction, lung anomaly, gastrointestinal problem, skin disorder, liver impairment, and kidney malfunction. Being aware of your child’s entire medical history will help the doctor make critical dose alterations and plan your child’s overall treatment.

Benefits of Domsettler Suspension for your child

Treatment of Indigestion
Indigestion means discomfort of mainly the upper part of your stomach which may also have other symptoms such as stomach pain, bloating, feeling full, etc. Domsettler Suspension improves the movement of food in your stomach and gut (intestine). This relieves these symptoms and helps in the proper digestion of food.

Take Domsettler Suspension as prescribed by the doctor. Think about what foods trigger indigestion and try to avoid them; eat smaller, more frequent meals; try to lose weight if you are overweight, and try to find ways to relax. Do not eat within 3-4 hours of going to bed.
Treatment of Gastroesophageal reflux disease (Acid reflux)
Gastroesophageal reflux disease (GERD) is a chronic (long-term) condition that is like having heartburn consistently rather than just occasionally. It happens because a muscle above the stomach relaxes too much and allows stomach contents to come back up into the esophagus and mouth. Domsettler Suspension helps treat this condition by increasing the tone of the lower end of the food pipe and preventing the entry of acid. You should give it to your child exactly as prescribed for it to be effective.

Side effects of Domsettler Suspension in children

Domsettler Suspension does not pose serious side effects and is well-tolerated by children. In case the side effects do occur, they’re likely to subside once the body adapts to the medicine. Consult your child’s doctor if these side effects persist or bother your child. The most common side effects include-
Common side effects of Domsettler
  • Dryness in mouth
  • Headache
  • Diarrhea
  • Drowsiness
  • Stomach cramp

How can I give Domsettler Suspension to my child?

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Domsettler Suspension is to be taken on an empty stomach.

How Domsettler Suspension works

Domsettler Suspension is a prokinetic. It works on the region in the brain that controls vomiting. It also acts on the upper digestive tract to increase the movement of the stomach and intestines, allowing food to move more easily through the stomach.

Quick tips

  • Domsettler Suspension should be taken before meals as per the dose and duration prescribed by the doctor.
  • Dry mouth may occur as a side effect. Frequent mouth rinses, good oral hygiene, increased water intake and sugarless candy may help.
  • If needed, Domsettler Suspension can be given along with fever medicines unless your child’s doctor has told you not to.
  • Do not mix Domsettler Suspension with any herbal or ayurvedic medicines as they can harm.
  • Give Domsettler Suspension for the current illness. Do not save medicines to treat future symptoms.
  • If you are not sure a medicine is working, do not stop the medicine abruptly by yourself. Call your child’s doctor for advice. Meanwhile, continue with the medicine.

Safety advice

Kidney

Kidney

CAUTION
Domsettler Suspension should be used with caution in patients with severe kidney disease. Dose adjustment may be needed.
Regular monitoring of renal function, particularly with long-term therapy, may be required.
Liver

Liver

UNSAFE
Domsettler Suspension is unsafe to use in patients with liver disease and should be avoided.
Use of Domsettler Suspension is not recommended in children with severe liver disease. Consult your child’s doctor before giving the medicine to your child.

Interaction with drugs

Taking Domsettler with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Chloroquine (Oral Route)

Do not consume Chloroquine with Domperidone. Concomitant use may affect heart rhythm.
Life-threatening

Loperamide (Oral Route)

Do not consume Loperamide with Domperidone.
Life-threatening

Levofloxacin (Oral Route)

Do not consume Levofloxacin with Domperidone.
Life-threatening

Levofloxacin (Injection Route)

Do not consume Levofloxacin with Domperidone.
Life-threatening

Ciprofloxacin (Oral Route)

Do not consume Ciprofloxacin with Domperidone.

Frequently asked questions

The maximum daily safe dose of Domsettler Suspension is 30mg/day. Giving more than this amount can cause heart-related problems in your child.
Domsettler Suspension is unlikely to cause harm if you give an extra dose by mistake. However, you must still speak to your child’s doctor immediately. Sometimes, excessive intake of Domsettler Suspension can cause some serious side effects like irregular heartbeats, heart block, agitation, and confusion. If any of these appear, consult the doctor without any delay.
Store Domsettler Suspension at room temperature, in a dry place, away from direct heat and light. Also, keep all the medicines out of the reach and sight of children to avoid any accidental intake.
Domsettler Suspension can sometimes interact with other medicines or substances. Tell your doctor about any other medicines your child is taking before starting Domsettler Suspension. Also, check with your child’s doctor before giving any medicine to your child.

Fact Box

Chemical Class

Benzimidazoles

Habit Forming

No

Therapeutic Class

GASTRO INTESTINAL

Action Class

Dopamine D2 Receptor Antagonists- Prokinetic Agents

References

  1. McQuaid KR. Drugs Used in the Treatment of Gastrointestinal Diseases. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 1078.
  2. National Health Service. Domperidone. [Accessed 29 Jan. 2021] (online) Available from:
  3. About Kids Health. Domperidone. [Updated 13 Aug. 2009]. [Accessed 29 Jan. 2021] (online) Available from:
  4. Patient. Domperidone for sickness. [Accessed 29 Jan. 2021] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Lifeon Paediatrics Ltd
Address: BSD Marg, Govandi, Mumbai 400088.

Vendor Details

Country of origin: India
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