Medicine Overview of Diclodyne Suppository
Diclodyne Anal 12.5 Suppository is used in pain relief
Side Effect of Diclodyne is Anal irritation.
Use this medicine in the dose and duration as advised by your doctor. Wash and dry the area. Lie down and gently insert the suppository into the area with or without the use of an applicator as mentioned in the label. You or your care giver may be taught on how to use this medicine at home.
Diclodyne Anal 12.5 Suppository is a non-steroidal anti-inflammatory drugs (NSAID) which is absorbed rapidly into the bloodstream from the rich blood supply of the rectal area. Once absorbed, it works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling).
In Depth Information on Diclodyne Suppository
- Inform your doctor if you have diabetes, angina, blood clots, and high blood pressure, raised cholesterol or raised triglycerides, liver disorder of the red blood pigment (porphyria).
- Tell your doctor if you had or need to have surgery.
- Avoid direct contact of gel/ lotion with your eyes. In case of direct contact, wash your eyes with water immediately and seek immediate medical attention.
- Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
- Do not use if you are allergic to diclofenac or any of its ingredients.
- Do not use if you previously had allergic reaction (asthma, hives or a cold) due to aspirin or other pain killers.
Diclodyne Suppository related warnings
No interaction found/established
WEIGH RISKS VS BENEFITS
Diclodyne Anal 12.5 Suppository may be unsafe to use during pregnancy.
Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
Diclodyne Anal 12.5 Suppository is probably safe to use during lactation.
Limited human data suggests that the drug does not represent a significant risk to the baby.
No interaction found/established
There is limited information available on the use of Diclodyne Anal 12.5 Suppository in patients with kidney disease. Please consult your doctor.
There is limited information available on the use of Diclodyne Anal 12.5 Suppository in patients with liver disease. Please consult your doctor.
Frequently asked questions about Diclodyne Suppository
Q. Is diclofenac topical a blood thinner / controlled substance?
Diclofenac is a pain relieving medication and it does not significantly affect the function of platelets in blood; hence it is not a blood thinner. It is not a controlled substance as it does not have the potential for abuse or addiction.
ER is a short name for 'Extended Release'. Diclodyne ER tablets deliver the drug Diclodyne for a prolonged period of time. This, in turn, decreases the number of tablets you swallow per day.
Q. Can I use Diclodyne along with vitamins?
Yes, Diclodyne can be taken with vitamins. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. Can Diclodyne be used for the treatment of hepatitis?
No, Diclodyne is not approved for the treatment of hepatitis. Hepatitis is a condition where the liver is inflamed. Diclodyne can, in fact, cause harm to the liver as a side effect.
Q. Can Diclodyne be used after C-section?
Yes, Diclodyne is a pain killer. C-section is the short name for Cesarean Section which is an operative procedure to deliver the baby through the mother's abdomen and uterus. Diclodyne can be used to treat the pain that may occur after the operation.
Q. What is the difference between Diclodyne and baclofen?
Diclodyne is a pain killer. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis. Baclofen is a depressant of the nervous system, used to relax the muscles and also used in to reduce pain. Baclofen is used for the treatment of spinal cord injury, cerebral palsy, and multiple sclerosis.
Q. What is the difference between Diclodyne and lidocaine?
Diclodyne is a pain killer. It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis. Lidocaine (also known as xylocaine and lignocaine) is a medication primarily used to numb tissue in a specific area before any surgical procedure and is also used to treat ventricular tachycardia (a condition where the beating rhythm of the heart gets disturbed.
Q. What is the Cmax of Diclodyne?
Cmax of Diclodyne (50 mg) is 3.9 µmol/l.
Q. Which is the best choice between Diclodyne and aceclofenac?
The researcher has proved that aceclofenac is a better alternative to Diclodyne with fewer side effects, especially in the treatment of osteoarthritis, ankylosing spondylitis. Both Aceclofenac and Diclodyne are NSAIDs (Non-Steroidal Anti-Inflammatory Drugs) and used as painkillers.
Diclodyne SR refers to the 'Sustained Release' preparation of Diclodyne. Sustained release preparations are designed to release Diclodyne at a known rate in order to maintain a constant drug concentration for a specific period of time with minimum side effects. This decreases the number of tablets you need to swallow with almost similar benefits.
Q. What is the half-life of Diclodyne?
The half-life of Diclodyne is 1-2 hours. This is the time required for the concentration or amount of drug in the body to be reduced by one-half.
Q. Which is the best choice between Diclodyne and ibuprofen for back pain?
Both Diclodyne and Ibuprofen can be used for back pain. Currently, there are not many studies which can identify the best treatment between the these two agents.
Q. Which is the best choice between Diclodyne and ibuprofen for a toothache?
Both Diclodyne and Ibuprofen can be used for toothache. Currently, there are not many studies which can identify the best treatment between the these two agents. However according to one study, a combination of Diclodyne with paracetamol has been found to be better then a combination of Ibuprofen and paracetamol.
Q. What is the difference between Diclodyne and meloxicam?
Meloxicam has been found to have fewer gastrointestinal side effects than Diclodyne and its use is associated with an increased risk of cardiovascular events such as heart attack and stroke.
Q. Can I use Diclodyne for the treatment of arthritis?
Yes, Diclodyne is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis, and spondylitis.It belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). .
Q. What is the difference between Diclodyne and naproxen?
In research studies, naproxen has been found to have lesser cardiovascular events like stroke and heart attack than Diclodyne. Another key variations naproxen may be more likely to be recommended for the treatment of inflammatory conditions in young patients as compared to Diclodyne.
Q. Can I take Diclodyne along with misoprostol?
Yes. It can be taken together. Misoprostol protects the stomach from irritating gastric effects of Diclodyne. The combination of medication is used to treat arthritis in patients at high risk of getting stomach/intestinal ulcers and complications from the ulcers (such as bleeding).
Q. Can I use Diclodyne for nerve pain?
Yes. Studies have shown Diclodyne (topical preparations) to be of use in nerve pain like Post-Herpetic pain.
Q. Can I use Diclodyne for eye management?
Yes. Diclodyne eye drops can be used to treat non-bacterial inflammation,e.g. post-operative state. Diclodyne eye drops have also been used to manage pain for traumatic corneal abrasion.
Q. Can I take Diclodyne while I am on thyroxine?
Yes, Diclodyne can be taken with thyroxine. No drug-drug interactions or any harmful effects have been reported when they are used together.
Q. What is the difference between Diclodyne potassium and Diclodyne sodium?
Diclodyne exists in two forms - the sodium salt (Diclodyne sodium) and the potassium salt (Diclodyne potassium). Each has the same amount of Diclodyne base - the main difference is that Diclodyne potassium is slightly more soluble in water than Diclodyne sodium.
Q. Can Diclodyne be used in the treatment of chikungunya?
Usually, the platelet count does not dip in cases of chikungunya and painkillers like Diclodyne can lead to a risk of increased bleeding tendency. So refrain from taking piroxicam or any pain killer in the case of any fever with joint pain. Consult your doctor before starting Diclodyne.
Q. Where is Diclodyne metabolised?
Diclodyne is metabolised in the liver.
Q. Can I use Diclodyne with diuretics?
No, Diclodyne should not be used with diuretics. Diclodyne reduces the natriuretic effect of furosemide and thiazides diuretics in some patients. This response has been attributed to inhibition of renal prostaglandin synthesis.
Q. Is Diclodyne a narcotic?
No, Diclodyne is not a narcotic. Narcotics are drugs with sleep inducing properties, usual derivatives of Opium like Heroin and Morphine.
Q. Why Diclodyne should be stopped before surgery?
Since Diclodyne has been shown to have blood thinning effects, it can increase the risk of bleeding. Therefore, it is stopped before surgery to prevent excessive loss of blood.
Q. Can Diclodyne be used along with warfarin?
No. Using Diclodyne together with warfarin can increase the risk of serious bleeding from the stomach (Higher than users of either drug alone). Inform your doctor before starting these medications.
Q. What are the contraindications for Diclodyne?
Diclodyne should not be used if there is an allergic reaction (hypersensitivity) to it, or other pain killers, active ulcer in the stomach, bleeding from the stomach, history of severe heart failure, liver failure, kidney failure and or heart attack.
Q. Is Diclodyne a painkiller?
Yes. Diclodyne is a pain killer. In fact, it belongs to the class of drugs called non-steroidal anti-inflammatory drugs (NSAIDs). It is commonly used for the treatment of pain in osteoarthritis, rheumatoid arthritis and spondylitis.
Q. Can Diclodyne affect the chance of conceiving?
Yes. Diclodyne can sometime cause reversible infertility. Diclodyne by its mechanism of action, may delay or prevent rupture of ovarian follicles, which has been associated with reversible infertility in some women. Consult your doctor before starting this medication.
Q. Why does Diclodyne cause an ulcer?
Diclodyne can cause damage to the lining cells of the stomach by several mechanisms, including the irritant effect on the cells, breaking of the protective barrier properties of lining cells, suppression of prostaglandin production of the stomach, reduction of stomach mucosal blood flow and interference with the repair of superficial injury of the stomach lining.
Q. Is Diclodyne good for back pain?
Yes, Diclodyne has been found to be effective to reduce back pain. Diclodyne is a pain killer that belongs to the NSAIDs (Non-Steroidal Anti-Inflammatory) class. Other NSAIDs have also been found to be useful in back pain eg. Ibuprofen and Naproxen.
Q. Why is Diclodyne contraindicated in asthma?
Some patients with asthma are hypersensitive to non-steroidal anti-inflammatory drugs (NSAID) like aspirin which can lead to acute attacks of asthma. Consult your doctor before starting this medication.
Q. Can I use Diclodyne during my fever treatment?
Yes, Diclodyne can reduce fever. However, commonly used to reduce the pain, particularly that which is seen with Osteoarthritis, Rheumatoid Arthritis and Ankylosing spondylitis.
Q. Can I use Diclodyne to treat a sore throat?
Sore throat is mostly caused by bacteria so antibiotics are given to treat a sore throat whereas Diclodyne is a pain killer so it can be given in cases of throat pain associated with it but only under the prescription of a doctor.
Q. Can I use Diclodyne with mifepristone?
These drugs should not be used together as the effect of mifepristone may be lowered by Diclodyne. Mifepristone is used for medical abortion.
Q. Can I use Diclodyne to treat urinary tract infections (UTI)?
Diclodyne can be used to treat the pain associated with urinary tract infection (UTI) but for complete treatment, a course of antibiotics will be required.
Q. Can Diclodyne cause sedation?
Diclodyne is not known to cause sedation. There have been rare, an isolated case report of sedation with the drug.
Q. Can I take Diclodyne for kidney stones?
Yes,Diclodyne can be used to relieve the pain due to kidney stones. However, there is also a risk of kidney damage with Diclodyne as its side effect. It is advised not to take Diclodyne for a prolonged time for this condition without adequate monitoring.
Q. Can I use Diclodyne with lithium?
No.These drugs should not be used together as Diclodyne increases the blood levels of lithium which may further increase the side effects.
Q. What is the difference between Diclodyne and ketoprofen?
Although both these agents are non-steroidal anti-inflammatory drugs (NSAIDs), there is a subtle difference in the way they act. Ketoprofen blocks the Cyclo-oxygenase (COX) enzyme without any preference for blocking of any one of this enzyme subtypes. Diclodyne has the preference to block COX-2 subtype of Cyclooxygenase enzyme. Blocking of COX reduces prostaglandins (chemicals naturally produced by the body that is responsible for pain and inflammation).
Q. Are Diclodyne and ibuprofen same?
No. Diclodyne and Ibuprofen are different medicines but they both belong to the same class of drugs i.e. Non-Steroidal Anti-inflammatory Drugs (NSAIDs). Both are commonly used as painkillers.
Q. Can smoking be harmful while i am
Yes. Smoking is a known risk factor causing an ulcer in the stomach. Diclodyne too can cause ulceration of stomach as a side effect. Both together may increase the chance of forming ulcer in the stomach and bleeding. Therefore it is advised to quit smoking while on Diclodyne therapy.
Q. How much of Diclodyne is absorbed?
Diclodyne is rapidly and completely absorbed from tablets. Food intake does not affect absorption.
Severely interacts with other drugs like
Taking Diclodyne with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
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