Dependal M Syrup

Reviewed By Dr. Sachin Gupta, MD Pharmacology, MBBS

Last updated on 10 Jan 2026 | 11:07 PM (IST)

Dependal M Syrup is a combination of two medicines that effectively treat diarrhea and dysentery. It prevents the growth of microorganisms to treat bacterial infections.

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General Information

Contains

Furazolidone (25mg)+ Metronidazole (75mg)

Marketer

Glaxo SmithKline Pharmaceuticals Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dependal M Syrup is a prescription medicine that is to be taken as per the prescription or as suggested by the doctor. It should be taken with food, but it must be taken at a fixed time to ensure better efficacy. Do not consume more than the recommended dose, as this may have harmful effects on your body. If you miss a dose, take it as soon as you remember. The treatment must be completed even if you feel better.

Dependal M Syrup may lead to some side effects such as nausea, headaches, dryness of mouth, etc. To overcome any such side effects, it is advised to eat a healthy balanced diet and drink plenty of fluid. Maintaining good oral hygiene can prevent or manage the dryness of the mouth. If any of the side effects get aggravated, contact your doctor immediately. If you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.), you must consult your doctor immediately.

Before taking this medicine, you should tell your doctor if you have any problems with your liver or kidneys. Also, tell your doctor if you are on any medication for any health condition. Pregnant or breastfeeding women should also consult with the doctors before taking it. Avoid drinking alcohol as it can cause excessive dizziness with this medicine. It usually does not impair your ability to drive, but you should not drive if it makes you feel sleepy or dizzy. If you are a known allergic to the medicine, you must refrain from using this medicine and consult your doctor. It is advised to take proper rest during the course of treatment for the medicine to work effectively.

Uses of Dependal M Syrup

Benefits of Dependal M Syrup

Diarrhea
Diarrhea is an increase in the frequency of bowel movements or loose watery bowel movements. It can most commonly occur due to an infection of the digestive tract. Dependal M Syrup helps to treat diarrhea that is caused due to bacteria or parasitic worm infections. This medicine can relieve frequent loose motions and also help you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Dysentery
Dysentery or amoebic dysentery is a parasitic infection of the intestines that occurs mostly due to intake of contaminated food or water. The symptoms include loose stools (diarrhea), stomach cramps and stomach pain. Dependal M Syrup helps to treat this infection by killing the infection causing parasites. It relieves these symptoms and also helps you to stay well by preventing them from coming back. You need to take this medicine regularly to get the most out of it and you should drink plenty of fluids while taking it to make sure you stay hydrated.

Side effects of Dependal M Syrup

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dependal M

Nausea
Headache
Dryness in mouth
Metallic taste
Dark yellow to brown discoloration of urine

How to use Dependal M Syrup

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Dependal M Syrup should be taken with or after food.
Avoid Dependal M Syrup with tyramine-rich food such as cheese, smoked fish, meats and some types of beer.

How Dependal M Syrup works

Dependal M Syrup is a combination of two antibiotics: Furazolidone and Metronidazole, which treats stomach and intestine infections. Furazolidone works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria in the human body. Metronidazole kills bacteria and other infectious microorganisms by damaging the DNA. Together, they treat your infection effectively.

Quick tips

Dependal M Syrup should be taken with food at the same time every day.
Do not skip any doses and finish the full course of treatment even if you feel better.
It is advisable to stay hydrated and drink plenty of water to overcome medicine side effects.
It may cause dizziness. Don't drive or do anything that requires mental focus until you know how Dependal M Syrup affects you.
Avoid alcohol consumption as it may cause excessive drowsiness.
Inform your doctor if you experience itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking this medicine.

Safety advice

Alcohol

UNSAFE

Consumption of alcohol with Dependal M Syrup may cause a disulfiram-like reaction, leading to symptoms such as flushing, increased heart rate, low blood pressure, nausea, lightheadedness, and severe headache.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Dependal M Syrup during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Dependal M Syrup may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Dependal M Syrup may cause side effects that could affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Dependal M Syrup in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Dependal M Syrup should be used with caution in patients with liver disease. Dose adjustment may be needed.

Frequently asked questions

Can I stop taking Dependal M Syrup when my symptoms are relieved?

No, do not stop taking Dependal M Syrup and complete the full course of treatment even if you feel better. Your symptoms may improve before the infection is completely cured.

Can the use of Dependal M Syrup cause metallic taste?

Yes, Dependal M Syrup can cause a temporary metallic taste. This metallic taste can be lowered by chewing sugar-free gum, mints and by brushing teeth after the meals.

Can I drink alcohol while taking Dependal M Syrup?

Avoid drinking alcohol while taking Dependal M Syrup and for at least 3 days after stopping the medicine. Drinking alcohol while taking this medicine may cause an unpleasant reaction (Disulfiram-like reaction) with symptoms like stomach pain, nausea, vomiting, headache, flushing or redness of the face.

What are the instructions for the storage and disposal of Dependal M Syrup?

Keep this medicine in the packet or container it came in, tightly closed. Store it according to the instructions mentioned on the pack or label. Dispose of the unused medicine. Make sure it is not consumed by pets, children and other people.

Fact Box

Habit Forming

Therapeutic Class

GASTRO INTESTINAL

Related lab tests

Stool Examination R/M

References

Quiros-Buelna E. Furazolidone and metronidazole for treatment of giardiasis in children. Scand J Gastroenterol Suppl. 1989;169:65-9. [Accessed 10 Jan. 2026]. Available from:

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Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Glaxo SmithKline Pharmaceuticals Ltd
Address: Dr. Annie Besant Road, Mumbai - 400 030

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Dependal M Syrup

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General Information

Contains

Marketer

Storage

Product introduction

Uses of Dependal M Syrup

Benefits of Dependal M Syrup

Side effects of Dependal M Syrup

How to use Dependal M Syrup

How Dependal M Syrup works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Frequently asked questions

Can I stop taking Dependal M Syrup when my symptoms are relieved?

Can the use of Dependal M Syrup cause metallic taste?

Can I drink alcohol while taking Dependal M Syrup?

What are the instructions for the storage and disposal of Dependal M Syrup?

Fact Box

Habit Forming

Therapeutic Class

Related lab tests

Stool Examination R/M

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests