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Degatide 80 Injection

Degarelix (80mg)

Genuine

Authenticity Assured

Prescription

required

Cold stored

Stored between 2-8°C

Product Summary :

Degatide 80 Injection contains degarelix, used to treat hormone-dependent prostate cancer in adult men. It works by lowering testosterone levels, which helps control cancer activity. It is also used before or in combination with radiotherapy for high-risk localized or locally advanced prostate cancer. Common side effects include hot flushes and injection-site reactions. Regular monitoring of prostate-specific antigen (PSA) and testosterone levels is important during treatment.

Written By Dr. Nikita Saini, MBA, MDS,
Reviewed By Dr. Dheeraj Kumar Sharma, PhD, M.Pharm,
Last updated on 15 Oct 2026 | 11:45 AM (IST)

₹12206 MRP ₹131257% off

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Degatide 80 Injection

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Same composition

Degrelax 80mg Injection

vial of 1 Injection

Degarelix (80mg)

by Zydus Lifesciences Ltd

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General Information

Contains

Degarelix (80mg)

Marketer

Cipla Ltd

Storage

Store in a refrigerator (2 - 8°C). Do not freeze.

The content is shown in English

Product introduction

Degatide 80 Injection is used in the treatment of advanced prostate cancer. It works by lowering the amount of testosterone produced in the body and restricts the growth of a cancer cell.

The dose and how often you take it depend on what you are taking it for. Your doctor will decide how much you need to improve your symptoms. You should take this medicine for as long as it is prescribed for you.

The most common side effects of this medicine include injection site reaction and hot flashes. If these bother you or appear serious, let your doctor know. There may be ways of reducing or preventing them.

Before taking this medicine, tell your doctor if you have ever had heart disease, diabetes, or liver disease. Your doctor should also know about all other medicines you are taking, as many of these may make this medicine less effective or change the way it works. Tell your doctor if you are pregnant or breastfeeding. Your doctor may check your blood for prostate-specific antigen (PSA) levels to see if the treatment is working.

Uses of Degatide Injection

Prostate cancer : Used to treat advanced prostate cancer that depends on male hormones to grow. It is also used before or along with radiotherapy for high-risk prostate cancer.

Benefits of Degatide Injection

Prostate cancer
Prostate cancer is a condition in which abnormal cells grow uncontrollably in the prostate gland, a small gland in men that produces seminal fluid. Degatide 80 Injection helps by lowering the levels of testosterone, a hormone that can promote the growth of prostate cancer cells. This slows down or stops cancer progression, reduces related symptoms, and helps improve quality of life.

Side effects of Degatide Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Degatide

Flushing (sense of warmth in the face, ears, neck and trunk)
Injection site reactions (pain, swelling, redness)

How to use Degatide Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Degatide Injection works

Degatide 80 Injection lowers the amount of testosterone (a male hormone) produced by the body. This may slow or stop the spread and growth of prostate cancer cells that need testosterone to grow.

Dosage

Degatide 80 Injection is administered as a subcutaneous injection into the abdominal region by a healthcare professional. Your doctor will determine the duration of treatment based on your prostate cancer condition, PSA levels, testosterone levels, and response to therapy. Do not change or discontinue treatment without consulting your doctor.

All substitutes for Degatide 80 Injection

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

Degatide 80 Injection helps in the treatment of advanced hormone-dependent prostate cancer.
It is given by injection under the skin (subcutaneously), usually in the stomach area.
It may cause hot flashes. Try wearing loose clothing and avoid alcohol, caffeine, and spicy foods.
Inform your doctor if you are diabetic or have problems with your heart, kidney or liver.
Your doctor may check the level of prostate specific antigen (PSA) in your blood. This is done to monitor how well Degatide 80 Injection is working for you. A decrease in PSA levels is usually a sign that your treatment is working.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Degatide 80 Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Information regarding the use of Degatide 80 Injection during pregnancy is not available. Please consult your doctor.

Breast feeding

CONSULT YOUR DOCTOR

Information regarding the use of Degatide 80 Injection during breastfeeding is not available. Please consult your doctor.

Driving

SAFE

Degatide 80 Injection does not usually affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Degatide 80 Injection in patients with kidney disease. Please consult your doctor.

Liver

CONSULT YOUR DOCTOR

There is limited data available on the use of Degatide 80 Injection in patients with liver disease.

Interaction with drugs

Taking Degatide with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Mizolastine (Oral Route)

Do not consume Mizolastine with Degarelix.

Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Severe

Artemether (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

What is Degatide 80 Injection used for?

Degatide 80 Injection is used in adult men to manage advanced hormone-dependent prostate cancer. It may also be given with radiotherapy in men with high-risk localized or locally advanced prostate cancer, either before treatment (neoadjuvant) or during treatment (adjuvant).

Who should not receive Degatide 80 Injection?

People should not receive Degatide 80 Injection if they are allergic to degarelix or any of its ingredients. It is not for use in women, children, or teenagers.

Can Degatide 80 Injection affect my heart rhythm?

Yes. Long-term therapy with Degatide 80 Injection may prolong the QT interval on ECG, which can increase the risk of abnormal heart rhythms. If you already have heart problems or take medicines that affect heart rhythm, your doctor will monitor your heart carefully before and during Degatide 80 Injection treatment.

Does Degatide 80 Injection affect the liver or kidneys?

Yes. If you have liver or kidney disease, Degatide 80 Injection should be used with caution. Mild changes in liver function tests can occur during treatment. Patients with severe liver or kidney impairment have not been well studied, so your doctor may monitor you more closely.

Can Degatide 80 Injection affect blood sugar levels?

Yes. Some men receiving Degatide 80 Injection may develop reduced glucose tolerance or worsening of diabetes. If you have diabetes, your doctor may check your blood sugar more often while you are on Degatide 80 Injection.

Does Degatide 80 Injection affect bone health?

Yes. Long-term testosterone suppression by Degatide 80 Injection may reduce bone density, increasing the risk of osteoporosis and fractures. Your doctor may recommend bone health monitoring during Degatide 80 Injection treatment.

What are the serious side effects of Degatide 80 Injection?

erious side effects of Degatide 80 Injection may include severe allergic reactions, chest pain, fainting, irregular heartbeat, difficulty breathing, yellowing of the skin or eyes, or persistent swelling at the injection site. Seek medical help immediately if you notice any of these symptoms.

Can Degatide 80 Injection cause cardiovascular problems?

Yes. Androgen deprivation therapy, including Degatide 80 Injection, has been linked to stroke, heart attack, and other cardiovascular diseases. If you have risk factors such as high blood pressure, diabetes, or smoking, your doctor will monitor your heart closely.

Can Degatide 80 Injection cause fertility problems?

Yes. Degatide 80 Injection lowers testosterone, which may reduce male fertility for as long as hormone levels remain suppressed. Fertility usually does not recover during treatment.

Fact Box

Chemical Class

Polypeptides

Habit Forming

Therapeutic Class

HORMONES

Action Class

Gonadotropin-releasing hormone (GnRH) Antagonists

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

User feedback

What are you using Degatide Injection for?

Prostate cancer

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Home

Hormones

Antigonadotrphin Releasing Hormones

Degatide 80 Injection

Degatide 80 Injection

Product Summary :

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Degatide Injection

Benefits of Degatide Injection

Side effects of Degatide Injection

How to use Degatide Injection

How Degatide Injection works

Dosage

All substitutes for Degatide 80 Injection

Firmagon 80mg Injection

Degrinta 80mg Injection

Degrelax 80mg Injection

Degarel 80mg Injection

Segarelix 80mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Mizolastine (Oral Route)

Amiodarone (Oral Route)

Amiodarone (Injection Route)

Artemether (Injection Route)

Artemether (Oral Route)

Frequently asked questions

What is Degatide 80 Injection used for?

Who should not receive Degatide 80 Injection?

Can Degatide 80 Injection affect my heart rhythm?

Does Degatide 80 Injection affect the liver or kidneys?

Can Degatide 80 Injection affect blood sugar levels?

Does Degatide 80 Injection affect bone health?

What are the serious side effects of Degatide 80 Injection?

Can Degatide 80 Injection cause cardiovascular problems?

Can Degatide 80 Injection cause fertility problems?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Prostate Specific Antigen (Free) PSA

Prostate Specific Antigen (Total) PSA

References

User feedback

What are you using Degatide Injection for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests