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Decitas Injection


Overview

Introduction

Decitas Injection is used in the treatment of blood cancer called acute myeloid leukaemia (AML). It is also used to treat patients with myelodysplastic syndrome (MDS). It may be used to treat other conditions, as determined by the doctor.

Decitas Injection is also used with certain other medicines as part of combination chemotherapy. It is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, headache, fever and lung infection. This medicine may reduce the number of blood cells (decrease red blood and white blood cells) in your blood, thereby, increasing the susceptibility to infections. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Before taking it, tell your doctor if have heart disease, liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. Use of effective contraception by both males and females during treatment is important to avoid pregnancy.

Uses of Decitas Injection

Side effects of Decitas Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Decitas

  • Nausea
  • Vomiting
  • Headache
  • Fever
  • Lung infection
  • Decreased white blood cell count (neutrophils)
  • Nosebleeds
  • Anemia (low number of red blood cells)
  • Low blood platelets
  • Diarrhea
  • Pneumonia

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with Nausea
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop from feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Vomiting
    You can help yourself by eating small, frequent meals rather than large ones and drinking plenty of fluids. Eat slowly. Avoid fatty, fried, spicy and very sweet foods. Eat cold or slightly warm food if the smell of cooked or cooking food makes you feel sick. Get plenty of fresh air. You could also try chewing ginger or drinking ginger tea. Eat bananas to replace potassium in your blood which can drop if you are sick (vomit). Use oral rehydration salts to replace vitamins and minerals lost through being sick. There are some medicines that can help you stop feeling sick. Speak to your doctor if your condition does not improve.
  • Coping with Headache
    Make sure you rest and drink plenty of fluids. Rest in a quiet, dimly lit room. Do not sleep more than you normally would. Do not strain your eyes (for example by looking at a screen). Do not drink alcohol. Headaches are usually temporary and usually go away with time. But, if they last longer or get worse, ask your doctor to recommend a painkiller.
  • Coping with Decreased white blood cell count (neutrophils)
    If you have a low level of white blood cells, you are more likely to get infections. There are several ways to reduce your chances of catching or spreading an infection. Avoid unnecessary exposure to germs when you can. Wash your hands frequently and thoroughly with soap or use a sanitiser. Avoid crowds and avoid contact with people who are ill or have infections. Use disposable tissues for coughs and sneezes. Consider using an appropriate face mask. Do not share personal items like cutlery, glasses, towels or toothbrushes with others. Get enough rest and eat a well balanced healthy diet.
  • Coping with Nosebleeds
    To stop a nosebleed, sit or stand upright (do not lie down). Pinch your nose just above the nostrils for a few minutes. Lean forward and breathe through your mouth. Place an icepack at the top of your nose. Get medical help if your nosebleed lasts more than 10 to 15 minutes. After a nosebleed, try not to blow your nose for 24 hours. Try to avoid hot drinks or alcohol.
  • Coping with Anemia (low number of red blood cells)
    Making some simple lifestyle changes can raise your red blood cell count. Reduce the amount of alcohol you drink, eat a well-balanced healthy diet and take regular exercise. Physical activities make your body need more oxygen and this stimulates the production of red blood cells. There are some vitamins which are important such as vitamin B-12, vitamin B-9, vitamin C and Vitamin A. Also, some minerals such as iron (especially) and copper. Aim for foods which contain higher quantities of these vitamins and minerals or ask your doctor for supplements. Make sure to consult your doctor for complete evaluation and treatment of anemia.
  • Coping with Low blood platelets
    You will need a blood test to find out if your blood platelet level is low. If this medicine is causing your platelet levels to drop, your doctor may suggest an alternative medicine. There are also medicines that can boost your blood platelet level. Consider asking your doctor about this. A low platelet count can put you at risk for bleeding. Try to be careful when doing activities that might cause an injury or a cut as it may take longer to stop bleeding.
  • Coping with Diarrhea
    Keep up your intake of fluids and electrolytes (sugars and salts) to avoid getting dehydrated. Eat less fiber (avoid raw fruits, fruit juice and vegetables). Talk to your doctor about possible medication to manage diarrhea. Ask about reducing the dosage of your drug or other suitable treatments.
  • Coping with Pneumonia
    Speak to your doctor if you feel unwell. Your doctor may be able to prescribe you certain medicines to treat your symptoms or prescribe you alternative medicines. Make sure you get plenty of rest. Stay away from school or work until you are better. Drink plenty of fluids to help loosen the mucus in your lungs and make you more comfortable. Avoid smoking as it will aggravate your condition.

How to use Decitas Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Decitas Injection works

Decitas Injection interferes with the growth of DNA and RNA of the cancer cells by substituting their building blocks. It prevents the cancer cells from growing and multiplying.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Decitas Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Decitas Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.
Breastfeeding
UNSAFE
Decitas Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving
UNSAFE
Decitas Injection may cause side effects which could affect your ability to drive.
You may feel tired or weak after using Decitas Injection this could affect your ability to drive.
Kidney
CAUTION
Decitas Injection should be used with caution in patients with kidney disease. Dose adjustment of Decitas Injection may be needed. Please consult your doctor.
Liver
CONSULT YOUR DOCTOR
There is limited information available on the use of Decitas Injection in patients with liver disease. Please consult your doctor.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Decitas Injection
₹4250.5/Injection
Deczuba 50mg Injection
Glenmark Pharmaceuticals Ltd
₹3401/Injection
save 20%
Natdecita Injection
Natco Pharma Ltd
₹5097.71/Injection
20% costlier
Xalibo 50mg Injection
Dr Reddy's Laboratories Ltd
₹5187/ml of Injection
22% costlier
Decitex 50mg Injection
Sun Pharmaceutical Industries Ltd
₹6229.39/Injection
47% costlier
Dacogen Injection
Johnson & Johnson Ltd
₹61430/ml of Injection
1345% costlier

Quick Tips

  • Use a reliable contraceptive method to prevent pregnancy while you are taking this medicine.
  • Inform your doctor immediately if you notice any signs of infection such as fever, sore throat, rash or severe diarrhea.

Patient Concerns

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Can blood cancer patients 1st stage do sex with normal girl Sir a blood cancer patients do sex with normal girl can any problem or cause doing with girl or side effect give suggestions Thanks
Dr. Vijay Sharnangat
Medical Oncology and Hematology
Wait till blood cancer gets cured.
Blood Cancer. Is there any medicine to cure blood cancer.
Dr. Aanchal Maheshwari
Ayurveda
Case has to be seen in person
arrow
Do you have any questions related to Decitas Injection ?

User Feedback


FAQs

Q. Is Decitas a vesicant?

Decitas is not a vesicant and is not known to cause severe local tissue damage upon extravasation (leaking of injected Decitas into the surrounding tissues from the site of administration) when injected

Q. How effective is Decitas?

The effectiveness of Decitas depends upon several factors including the patient's clinical condition, number of treatment cycles etc. and may vary depending upon the individual response

Q. Does Decitas cause hair loss?

Yes. Hair loss (alopecia) is among the known side effects of Decitas

Q. How is Decitas administered?

Decitas comes as a powder to be to be added to fluid and injected slowly over 3 hours into a vein (slow i.v infusion) by a doctor who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.

Related Products

Disclaimer:

1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

  1. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. p. 364.
  2. Decitabine. High Wycombe, Bucks: Janssen-Cilag Ltd.; 2012 [revised 07 Feb. 2019]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  3. Decitabine. Netherlands: Pharmachemie B.V.; 2006 [revised date]. [Accessed 26 Mar. 2019] (online) Available from:External Link
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:External Link

Manufacturer/Marketer Address

Chinubhai Centre, Off. Nehru Bridge, Ashram Road, Ahmedabad - 380009. Gujarat. India.
A licensed vendor partner from your nearest location will deliver Decitas Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.
MRP4250.5  Get 15% OFF
Best Price
₹3612.93
1 Injection in 1 vial
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