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Daunomac 20 Injection

Daunorubicin (20mg)
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Daunomac 20 Injection is used for the treatment of blood cancer (leukemia). It works by interfering with the growth of cancer cells, which are eventually destroyed.

Written By Dr. Subita Alagh, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Apr 2026 | 04:20 PM (IST)
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General Information

The content is shown in English
Daunomac 20 Injection image
Daunomac 20 Injection image
Daunomac 20 Injection image
Daunomac 20 Injection image

Product introduction

Daunomac 20 Injection is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include nausea, vomiting, low platelet count, ulcer, loss of appetite and difficulty while breathing. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, ECG, and physical examinations both before and during treatment with this medicine.

Uses of Daunomac Injection

Benefits of Daunomac Injection

Blood cancer
Blood cancer, such as leukemia, is a condition where the bone marrow produces abnormal white blood cells that grow uncontrollably and crowd out healthy cells. This leads to problems like frequent infections, fatigue, anemia, and bleeding issues. Daunomac 20 Injection works by targeting and destroying these rapidly growing cancer cells, slowing their spread and helping restore the balance of healthy blood cells. Overall, it plays an important role in controlling the disease, reducing symptoms, and improving treatment outcomes in patients with blood cancer.

Side effects of Daunomac Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Daunomac
  • Nausea
  • Vomiting
  • Low blood platelets
  • Ulcer
  • Abdominal pain
  • Loss of appetite
  • Decreased white blood cell count
  • Hair loss
  • Fever
  • Decreased blood cells (red cells, white cells, and platelets)
  • Fatigue
  • Anemia (low number of red blood cells)
  • Chills
  • Diarrhea
  • Mucosal inflammation
  • Febrile neutropenia
  • Stomatitis (Inflammation of the mouth)
  • Breathing problems

How to use Daunomac Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Daunomac Injection works

Daunomac 20 Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

Quick tips

  • Daunomac 20 Injection is given as an injection into the vein under the supervision of a doctor.
  • Do not skip any dose and complete the course as suggested by your doctor.
  • Use an effective method of birth control to avoid pregnancy while taking this medication.
  • Your doctor may get regular blood tests done to monitor your electrolyte levels, liver function, blood cell count in your blood.
  • You may be monitored with ECG before and after starting the treatment.
  • Let your doctor know if you experience fever, chills and some kind of infection during the treatment.

Safety advice

Alcohol

Alcohol

CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Daunomac 20 Injection. Please consult your doctor.
Pregnancy

Pregnancy

CONSULT YOUR DOCTOR
Daunomac 20 Injection is not recommended during pregnancy as there is positive evidence of fetal risk based on animal studies. However, it may still be prescribed by a doctor in situations where the benefits outweigh the risks.
Breast feeding

Breast feeding

UNSAFE
Daunomac 20 Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.
Driving

Driving

CONSULT YOUR DOCTOR
It is not known whether Daunomac 20 Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
Kidney

Kidney

CAUTION
Daunomac 20 Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Use of Daunomac 20 Injection is not recommended in patients with severe kidney disease.
Liver

Liver

CAUTION
Daunomac 20 Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
Use of Daunomac 20 Injection is not recommended in patients with severe liver disease.

Interaction with drugs

Taking Daunomac with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Life-threatening

Sargramostim (Injection Route)

Do not consume Daunorubicin from 1 day before until 1 day after taking Sargramostim. Please consult your doctor. Daunorubicin may reduce the efficacy of Sargramostim.
Severe

Amiodarone (Oral Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Amiodarone (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Arsenic Trioxide (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.
Severe

Artemether (Injection Route)

Factors such as old age, chronic heart issues, or low potassium levels may more frequently cause disturbance in heart rhythm, and your doctor may consider ECG monitoring in their presence.

Frequently asked questions

Yes. Daunomac 20 Injection is a vesicant (irritant) and can cause severe tissue damage upon extravasation (leaking of injected Daunomac 20 Injection into the surrounding tissues from the site of administration) when injected.
Daunomac 20 Injection is used in combination with other cancer medications to subside the progression of different types of blood cancers such as cancer of the white blood cells (acute myeloid and acute lymphocytic leukemia).
Daunomac 20 Injection comes as a solution or powder to be added to fluid and injected into a vein (intravenous) along with other chemotherapy medications. It is given as an injection by a cancer specialized doctor (oncologist) who is experienced in giving chemotherapy medications for cancer in a hospital or a clinic.
The frequency and duration of Daunomac 20 Injection treatment depends on the other chemotherapy medications you are taking, how well your body responds to them, and the type of cancer you have. Your doctor will decide the dose and frequency for you based on different parameters. For any doubts, consult your doctor.
Daunomac 20 Injection is an anti-cancer drug which belongs to the class of medicines called anthracycline cytotoxic antibiotics. The exact mechanism for its clinical effects is not clear; however multiple mechanisms directly interfering with important DNA processes and cell division are thought to be responsible for slowing or stopping the growth of cancer cells.

Fact Box

Chemical Class

Anthracyclines

Habit Forming

No

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Cytotoxic Alkaloids

References

  1. Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 952.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 362-63.
  3. Daunorubicin hydrochloride. Surrey, UK: Zentiva; 1994 [revised 31 Jul. 2018]. [Accessed 24 Jun. 2019] (online) Available from:
  4. Central Drugs Standard Control Organisation (CDSCO). [Accessed 27 Mar. 2019] (online) Available from:
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Admac Pharma Ltd
Address: SCO 84, Sector 5, Panchkula (Haryana), 134112 INDIA.

Vendor Details

Country of origin: India
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