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18 Feb 2020 | 05:25 PM (IST)
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Dargen 25 Injection

Prescription Required
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Overview

Introduction

Dargen 25 Injection is used in the treatment of anemia that may have occurred due to chronic kidney disease or chemotherapy. It works by stimulating the bone marrow to produce more red blood cells.

Dargen 25 Injection is a medicine that needs to be used with utmost care because it can lead to serious side effects. It is important that you seek treatment from a doctor who is experienced in providing this medicine therapy. You should follow all the directions of doctor strictly. It is given under the supervision of a healthcare professional. However, you should not take it, if you have any known allergy from this medication.

It may cause side effects like high blood pressure, and hypersensitivity. You should check your blood pressure regularly while taking this medication. Inform your doctor if there are symptoms of very high blood pressure such as severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).

Your doctor may get your blood tests done regularly to monitor the levels of salts (electrolytes such as potassium), haemoglobin and blood cells in your blood. You should stop taking it and consult with doctor if you develop shortness of breath or skin rash.

Side effects of Dargen Injection

Common
  • High blood pressure
  • Hypersensitivity

How to cope with side effects?

The occurrence of side effects varies from person to person. The following are a few ways of dealing with some of the common side effects. However, consult your doctor if these persist.

  • Coping with High blood pressure
    You can reduce your blood pressure by eating less salt, eating more fruit and vegetables, reducing the amount of alcohol you drink, being more active and losing weight. You could also reduce your caffeine intake (found in tea, coffee and cola drinks). Also, if you smoke, seek advice about quitting. High blood pressure can be treated with a range of different medicines. You should ask your doctor whether you need medication. Keep in touch with your doctor and get your blood pressure checked regularly.

How to use Dargen Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dargen Injection works

Dargen 25 Injection is an erythropoiesis-stimulating agent (ESA). It works by stimulating the bone marrow (soft tissue inside the bones which produces red blood cells) to produce more red blood cells.

Safety Advice

Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Dargen 25 Injection. Please consult your doctor.
Pregnancy
CONSULT YOUR DOCTOR
Dargen 25 Injection may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
Breastfeeding
SAFE IF PRESCRIBED
Dargen 25 Injection is probably safe to use during breastfeeding. Limited human data suggests that the drug does not represent any significant risk to the baby.
Driving
SAFE
Dargen 25 Injection does not usually affect your ability to drive.
Kidney
SAFE IF PRESCRIBED
Dargen 25 Injection is safe to use in patients with kidney disease. No dose adjustment of Dargen 25 Injection is recommended.
Liver
CAUTION
Dargen 25 Injection should be used with caution in patients with liver disease. Dose adjustment of Dargen 25 Injection may be needed. Please consult your doctor.

What if you forget to take Dargen Injection?

If you miss a dose of Dargen 25 Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
Dargen 25 Injection
₹1523.0/ml of Injection
Darbatitor 25mcg Injection
Torrent Pharmaceuticals Ltd
₹1585/ml of Injection
4% costlier
₹1650/ml of Injection
8% costlier
Cresp 25 Injection
Dr Reddy's Laboratories Ltd
₹1749/ml of Injection
15% costlier
Darcept 25 Injection
LG Lifesciences
₹1800/ml of Injection
18% costlier
₹1850/ml of Injection
21% costlier

Quick Tips

  • Dargen 25 Injection helps in the treatment of anemia that may have occurred due to chronic kidney disease or cancer chemotherapy.
  • It is given as a single injection under your skin.
  • Your doctor may get your blood tests done regularly to monitor the levels of hemoglobin, blood cells and electrolytes such as potassium in your blood.
  • Monitor your blood pressure regularly while taking this medication. Inform your doctor if you notice symptoms of very high blood pressure such as  severe headache, problems with your eyesight, nausea, vomiting or fits (seizures).
  • Stop taking Dargen 25 Injection and inform your doctor if you develop shortness of breath or skin rash.

Patient Concerns

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Blood Hb is found 5.9 so wat is it
Dr. Ila Jain Khandelwal
Pathology
Dear PATIENT from 1mg. The hemoglobin is very low, which can be due to anemia. I suggest you should consult a Hematologist /Physician for this.
how to resolve the problem of anemia?
Dr. Rekha Pohani
Dietetics/Nutrition
Intake of dates and jaggery will help
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Do you have any questions related to Dargen 25 Injection ?

User Feedback


FAQs

Q. How long does it take for Dargen to start working?

You will be able to notice an increase in the count of red blood cells (hemoglobin levels) in 2-6 weeks of starting Dargen.

Q. Is Dargen safe to use?

Dargen is a medicine that needs to be used with utmost care because it can lead to serious side effects and even death of the patient. It is important that you seek treatment from a doctor who is experienced in providing Dargen therapy. Follow all the directions strictly.

Q. I had started feeling better when my treatment with Dargen had just began, but now I feel tired and lack energy. What can be the reason and what should be done?

I had started feeling better when my treatment with Dargen had just begun, but now I feel tired and lack energy. What can be the reason and what should be done?

Q. Other than PRCA, can there be other reasons for not responding to Dargen?

You may not respond to Dargen if you have deficiencies of iron, folic acid or vitamin B12. It is important that you take measures to correct these deficiencies. Other reasons behind not responding to the treatment could be bleeding, infections, inflammation and bone marrow fibrosis.

Q. Can Dargen be used in children?

Yes, Dargen is used to treat anemia due to chronic kidney disease in children who are above 1 year of age. The effectiveness of Dargen and side effects seen in children are similar to adults.

Q. Can Dargen affect blood pressure?

Yes, Dargen can affect blood pressure. During initial therapy blood pressure should be monitored and those who have high blood pressure should take appropriate measures to control blood pressure. Your doctor may stop Dargen if the blood pressure remains uncontrolled.

Related Products

Disclaimer: 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover all possible side effects, drug interactions or warnings or alerts. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.
References
  1. Kaushansky K, Kipps TJ. Hematopoietic Agents: Growth Factors, Minerals, and Vitamins. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. pp. 1071-72.
  2. Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 358-59.
  3. ScienceDirect. Darbepoetin alfa. [Accessed 07 Apr. 2019] (online) Available from:External Link
  4. Darbepoetin alfa. Milton Road, Cambridge: Amgen Ltd.; 2001 [revised Sep. 2017]. [Accessed 23 Jan. 2019] (online) Available from:External Link
  5. Darbepoetin alfa. Thousand Oaks, CA: Amgen Inc.; 2001. [Accessed 07 Apr. 2019] (online) Available from:External Link
Manufacturer/Marketer Address
Lupin Ltd, 3rd floor Kalpataru Inspire, Off. W E Highway, Santacruz (East), Mumbai 400 055. India
Best Price
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0.42 ml in 1 prefilled syringe
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