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Dapsib Gel is a combination medicine that is used to treat acne. It minimizes excessive oil production, thus reducing inflammation. It also prevents the growth of the microorganisms that cause acne. This also helps to prevent pimples, blackheads, and whiteheads on the skin.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 11 Mar 2026 | 09:30 PM (IST)
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Dapsib Gel
Dapsib Gel
tube of 15 gm Gel
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Same composition
acnedap PLUS Gel
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tube of 15 gm Gel
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Dapsib Gel image
Dapsib Gel image

Product introduction

Dapsib Gel is only meant for external use and should be used as advised by your doctor. A thin layer of the medicine should be applied only to the affected areas of the skin with clean and dry hands. Wash your hands before and after applying the medicine. If it gets into your eyes, nose, mouth, or vagina, rinse with water. It may take several days to weeks for your symptoms to improve, but you should keep using this medicine regularly. The course of the treatment should be completed to ensure better efficacy of the medicine. If your condition does not improve or gets worse, you should talk to your doctor.


This is usually a safe medicine; however, it may cause dryness, peeling, redness, and a burning sensation at the application site. These side effects are usually mild and self-limiting. Most of these side effects can be prevented by using a skin moisturizer and drinking plenty of water. Serious side effects are rare. You must consult the doctor if you experience any allergic reaction (rashes, itching, swelling, shortness of breath, etc.).


Before using this medicine, it is important to tell your doctor if you are taking or have recently taken any other medicines for the same disease or other diseases. Pregnant and breastfeeding women should use this medicine with proper consultation and caution. If you are known to be allergic to the medicine, you must refrain from using this medicine and consult your doctor. During the course of the treatment, do not touch, prick or scratch the infected skin areas as this may worsen or spread the acne. Avoid unnecessary sun exposure and use sunscreen before stepping out in the sun. It is also advised not to receive any cosmetic procedures without asking your doctor.

Uses of Dapsib Gel

Benefits of Dapsib Gel

Treatment of Acne
Dapsib Gel helps treat acne by reducing the production of excessive oil in the skin. This helps keep your pores open and prevent further acne breakouts. It helps reduce redness and swelling around acne and promotes healing. It also helps reduce acne blemishes and gives you smoother-looking skin. Dapsib Gel usually takes a few weeks to have a noticeable effect so keep using it even if it appears not to be working. This medicine will help improve your mood and uplift your confidence as acne reduces.

Side effects of Dapsib Gel

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Dapsib
  • Dryness
  • Skin irritation
  • Itching
  • Burning sensation at the site of application
  • Erythema (skin redness)

How to use Dapsib Gel

This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and apply the gel. Wash your hands after applying, unless hands are the affected area.

How Dapsib Gel works

Dapsib Gel is a combination of two medicines: Dapsone and Adapalene which treat acne (pimples). Dapsone is an antibiotic which stops the bacteria from producing folic acid, a nutrient required for bacterial multiplication. $ame2 is a form of vitamin A which prevents the accumulation of sebum (skin’s natural oil), unblocks the pores, and allows natural exfoliation of the outer layers of skin.

All substitutes for Dapsib Gel

For information purposes only. Consult a doctor before taking any medicine.

Quick tips

  • Dapsib Gel must be applied as a thin layer on the affected area as prescribed by your doctor.
  • Do not use this medicine more often or for longer than advised by your doctor.
  • Before each application, wash the affected area with soap and water and dry well. 
  • Avoid getting it in the eyes, mouth or nose. Rinse with cold water if you accidentally get it in these areas.
  • It makes your skin sensitive towards sunlight. Use a sunscreen or wear protective clothing while going out.
  • It is advisable to avoid any kind of facial waxing or cosmetic procedure during acne treatment.

Safety advice

Alcohol

Alcohol

No interaction found/established
Pregnancy

Pregnancy

UNSAFE
Dapsib Gel is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding

Breast feeding

SAFE IF PRESCRIBED
Available human data suggest that the drug does not pass into breast milk in clinically significant amounts and is unlikely to harm the infant.
Driving

Driving

No interaction found/established
Kidney

Kidney

No interaction found/established
Liver

Liver

No interaction found/established

Frequently asked questions

Dapsib Gel is used for the treatment of moderate to severe acne vulgaris. The combination of a topical antibiotic and a retinoid addresses both the bacterial and comedonal aspects of acne. It reduces inflammation by minimizing excessive oil production and also prevents the growth of the microorganisms that cause acne.
You should not apply Dapsib Gel to open cuts, scrapes, sunburned, or irritated skin, as it can make your skin much more sensitive and increase the risk of burning, redness, or irritation.<br>
Though they are rare, severe side effects of Dapsib Gel may include allergic reactions such as rash, hives, swelling of the face, lips, tongue, difficulty breathing, or severe dizziness. If you notice these signs, stop using Dapsib Gel and seek emergency medical help.
Dapsib Gel is generally not recommended for children under twelve years of age, as safety and effectiveness have not been well established in this age group.
Some patients may notice temporary skin discoloration or dark marks at the Dapsib Gel application site, particularly if used with other skin products like benzoyl peroxide. This effect is usually reversible once treatment is stopped.
Stop using Dapsib Gel if you have persistent or worsening irritation, burning, swelling, skin discoloration, or if you experience any serious side effects. Always contact your doctor for advice if you are concerned about a reaction or lack of improvement.
Yes, you can use non-comedogenic makeup or sunscreen, but allow the Dapsib Gel to fully absorb before applying anything else to your skin to reduce the chance of irritation or interference with your acne treatment.

Fact Box

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User feedback

Once A Day
92%
Twice A Day
8%
Acne
100%
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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Indiabulls pharmaceutical ltd
Address: Indiabulls Pharmaceuticals Limited is M – 62 & 63, First Floor, Connaught Place, New Delhi – 11000

Vendor Details

Country of origin: India
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