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MRP: Rs. 125 for 1 tube(s) (15 GM gel each)
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food interaction for DAPLE-C

alcohol interaction for DAPLE-C

pregnancy interaction for DAPLE-C

lactation interaction for DAPLE-C

There is no data available. Please consult doctor before consuming the drug.
Interaction with alcohol is unknown. Please consult your doctor.
Daple-c gel may be unsafe to use during pregnancy.
Either animal studies have shown adverse effect on fetus and there are no human studies or studies in human and animals are not available. It should be given only if potential benefits justifies risk to the fetus. Please consult your doctor.
Daple-c gel is probably safe to use during breastfeeding. Please consult your doctor.


Adapalene Topical(0.1% w/w)


Adapalene is used topically for the treatment of severe acne on the face, chest, back, spots and pimples.

How it works

Adapalene belongs to the class of medications called as retinoid-like compounds. It exhibits an anti-inflammatory effect and reduces soreness and irritation. It works by stopping pimple formation under the surface of the skin and helps the skin to renew.

Common side effects

Application site itching, Burning sensation, Tingling sensation, Scaling of skin, Skin redness
Clindamycin Topical(1% w/w)


Clindamycin topical is used to treat severe acne (acne vulgaris) and vaginal infections caused by certain bacteria.

How it works

Clindamycin belongs to a class of medications called as lincomycin antibiotics. It inhibits the synthesis of essential bacterial proteins thereby stopping bacterial growth. In case of acne, in addition to killing of bacteria, clindamycin prevents spread of infection by reducing the free fatty acids on the skin surface that clog the pores of skin and promote overgrowth of bacteria.

Common side effects

Burning sensation, Application site irritation, Dry skin, Itching, Application site redness of skin


7 Substitutes
Sorted By
    (15 GM gel in tube)
    Glenmark Pharmaceuticals Ltd
    Rs. 17/GM of gel
    Rs. 255
    pay 104% more per GM of gel
  • ACNOVATE 0.1% W/W/1% W/W GEL
    (15 GM gel in tube)
    Apex Laboratories Pvt Ltd
    Rs. 12.07/GM of gel
    Rs. 181
    pay 45% more per GM of gel
  • ACNICIN 0.1% W/W/1% W/W GEL
    (15 GM gel in tube)
    Alembic Pharmaceuticals Ltd
    Rs. 8.21/GM of gel
    Rs. 123.15
    save 1% more per GM of gel
    (20 GM gel in tube)
    Micro Labs Ltd
    Rs. 8.20/GM of gel
    Rs. 164
    save 2% more per GM of gel
  • ADACIN 0.1% W/W/1% W/W GEL
    (15 GM gel in tube)
    Ajanta Pharma Ltd
    Rs. 11.93/GM of gel
    Rs. 179
    pay 43% more per GM of gel

Expert advice for DAPLE-C

  • Avoid contact of cream/ gel with the eyes, lips, mouth or angles of the nose, and other sensitive areas of the body. 
  • Avoid excessive sun exposure and wear protective clothing while using adapalene topical. Use of sunscreen products and protective clothing over the treated area.
  • Tell your doctor if you are pregnant, planning to become pregnant or are breastfeeding.
  • Do not use if you are allergic to adapalene or any of its ingredients.

Frequently asked questions for DAPLE-C

Adapalene Topical

Q. Is adapalene/Differin/Adaferin a steroid or statin?
No, adapalene, Differin (brand name for adapalene, Adaferin (brand name for adapalene) belong to class of medications called retinoid-like compounds.
Q. Is adapalene topical good for wrinkles?
In some clinical studies, anti-wrinkle effect of adapalene has been observed. However, consult your doctor regarding its use.
Q. Is adapalene the same as Retin-A?
No, Adapalene is a medication that works in the same way as Retin-A, but it is more effective than Retin-A.
Q. Does adapalene topical reduces acne scars?
Yes, adapalene topical reduces acne scars.
Q. Does adapalene topical cause skin exfoliation?
Yes, it may sometime cause skin exfoliation.

Clindamycin Topical

 Q. Can I use clindamycin with a penicillin allergy?
Clindamycin is considered safe for use in patients with a penicillin allergy.
Q. Does clindamycin treat acne scars?
Clindamycin can prevent the formation of new scars by preventing formation of new acne, but will not be useful for the scars already formed.
Q. Can clindamycin cream cause thrush?
Yes. Use of clindamycin cream may cause thrush (a type of fungal or yeast infection) in rare cases.


Content on this page was last updated on 09 July, 2015, by Dr. Varun Gupta (MD Pharmacology)