Dalimune 50mg Tablet

Dolutegravir (50mg)

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Dalimune 50mg Tablet belongs to a group of medicines called antiretrovirals. It is used to treat HIV (human immunodeficiency virus), the virus that can cause AIDS (acquired immunodeficiency syndrome). It prevents the multiplication of viruses in human cells and clears up your infection.

Written By Dr. Sakshi Jain, MS, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 14 Apr 2026 | 04:21 PM (IST)

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Dalimune 50mg Tablet

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Instgra Tablet

bottle of 30 tablets

Dolutegravir (50mg)

by Emcure Pharmaceuticals Ltd

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General Information

Contains

Dolutegravir (50mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dalimune 50mg Tablet is not a cure for HIV or AIDS and only helps to decrease the amount of HIV in your body. This helps to lower your risk of getting HIV-related complications and improves your lifespan. It is prescribed in combination with other HIV medicines. Your doctor will recommend the best medicines for you and will decide the doses that you need. Follow the instructions carefully, for all the medicines that you are given. It may be taken with or without food, preferably at a fixed time. Taking all these medicines regularly at the right times greatly increases their effectiveness and reduces the chances of HIV becoming resistant to them. It is important not to miss doses and to keep taking them until your doctor tells you it is safe to stop.

Some common side effects include headache, insomnia (difficulty sleeping), dizziness, diarrhea, nausea, and fatigue. These are usually not serious but tell your doctor if they bother you or persist for a longer duration. Rarely, some people may experience a skin reaction or liver damage. Your doctor will closely monitor you for these in the initial period of treatment.

Before taking it, tell your doctor if you have any skin problems or liver or kidney disease. While using it, you may need regular blood tests to check your blood counts and liver function. Avoid drinking alcohol as it may increase your risk of liver damage. Pregnant or breastfeeding mothers should consult their doctor before using this medicine. Do not have unprotected sex or share personal items like razors or toothbrushes, if you are HIV positive. Talk to your doctor about safe ways like condoms to prevent HIV transmission during sex.

Uses of Dalimune Tablet

HIV infection

Benefits of Dalimune Tablet

HIV infection
Dalimune 50mg Tablet prevents HIV from multiplying in the body. It helps control the infection and make the immune system work better. This lowers the chances of getting complications, such as new infections, and improves the quality of life. This medicine is always taken in combination with other antiretroviral medicines.

It is not a cure of HIV or AIDS and should not be used to prevent HIV after accidental exposure to a risk. It is important to take this medicine as prescribed by the doctor. Taking all doses in the right amount at the right times greatly increases the effectiveness of this combination of medicines and reduces the chances of HIV infection becoming resistant to antiretroviral medicines. Although taking this medicine does not prevent the passing of HIV to other people.

Side effects of Dalimune Tablet

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dalimune

Insomnia (difficulty in sleeping)
Dizziness
Diarrhea
Nausea
Fatigue
Muscle pain
Increased liver enzymes
Stomach pain
Itching
Abnormal dreams
Anxiety
Headache

How to use Dalimune Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Dalimune 50mg Tablet may be taken with or without food.

How Dalimune Tablet works

Dalimune 50mg Tablet is an anti-HIV medication. It prevents the multiplication of virus in human cells. This stops the virus from producing new viruses and clears up your infection.

All substitutes for Dalimune 50mg Tablet

For information purposes only. Consult a doctor before taking any medicine.

Instgra Tablet

by Emcure Pharmaceuticals Ltd

₹104.47/tablet

45% costlier

Quick tips

Take Dalimune 50mg Tablet with or without food, preferably at the same time everyday.
Do not skip any doses and finish the full course of treatment even if you feel better.
Do not take antacids or calcium supplements an hour before or two hours after taking Dalimune 50mg Tablet.
Your doctor may monitor your liver function regularly during treatment. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CAUTION

Alcohol should be used with caution while taking Dalimune 50mg Tablet.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Dalimune 50mg Tablet during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Dalimune 50mg Tablet may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Dalimune 50mg Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.

Kidney

SAFE IF PRESCRIBED

Dalimune 50mg Tablet is safe to use in patients with kidney disease. No dose adjustment is recommended.

Liver

CAUTION

Dalimune 50mg Tablet should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Dalimune with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Moderate

Apalutamide (Oral Route)

Talk to your doctor if you notice any unusual symptoms. Apalutamide may increase the metabolism of Dolutegravir.

Moderate

Bosentan (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Bosentan may reduce blood levels of Dolutegravir.

Moderate

Calcium (Oral Route)

To take Dolutegravir, ensure a gap of at least 2 hours before or 6 hours after taking Calcium. If Calcium is taken with food, Dolutegravir can be taken at the same time as well. Dolutegravir may increase the metabolism of Calcium.

Moderate

Carbamazepine (Oral Route)

When consuming Dolutegravir and Carbamazepine together, it's important to consult your doctor. They can provide guidance on whether it's safe to consume them together and adjust the treatment plan accordingly. Dolutegravir may increase the rate of release of Carbamazepine in the blood.

Moderate

Dabrafenib (Oral Route)

If concurrent use is essential, your doctor may monitor your treatment and adjust the doses as per the observations. Dabrafenib may reduce blood levels of Dolutegravir.

Frequently asked questions

What is Dalimune 50mg Tablet used for?

Dalimune 50mg Tablet is a medicine that helps treat HIV infection by lowering the amount of virus in your body. It is used along with other HIV medicines to keep your immune system strong.

Who should not take Dalimune 50mg Tablet?

Individuals should not take Dalimune 50mg Tablet if they are allergic to it or any ingredients in the medicine. Also, it should not be used with certain medicines like dofetilide and fampridine because of dangerous interactions.

Are there any serious warnings with Dalimune 50mg Tablet?

Yes, if you develop a severe skin rash, swelling, fever, tiredness, or liver problems, stop taking Dalimune 50mg Tablet and contact your doctor immediately. These could be signs of a serious allergic reaction.

Can Dalimune 50mg Tablet affect my mood or mental health?

Some people may feel depressed, anxious, or have trouble sleeping while taking Dalimune 50mg Tablet. If these feelings become severe or you have thoughts of harming yourself, tell your doctor right away.

What should I know about liver health while taking Dalimune 50mg Tablet?

Dalimune 50mg Tablet can affect your liver, especially if you have hepatitis B or C. Your doctor will likely monitor your liver tests during treatment to catch any problems early.

Does Dalimune 50mg Tablet cause weight changes or affect metabolism?

Some people may gain weight or see changes in blood fats and sugar levels while on Dalimune 50mg Tablet treatment. Your doctor will check these regularly to ensure your health remains stable.

Can Dalimune 50mg Tablet be used in children and older adults?

Yes, Dalimune 50mg Tablet is approved for children weighing at least 20 kilograms and adults, including some elderly patients. Dose may vary, so always follow your doctor’s instructions.

How long does it take for Dalimune 50mg Tablet to work?

Dalimune 50mg Tablet works over several weeks to lower the HIV level. It is important to keep taking your medicine exactly as prescribed, even if you feel well.

Fact Box

Chemical Class

Pyridinecarboxylic acid derivative

Habit Forming

Therapeutic Class

ANTI INFECTIVES

Action Class

Integrase Strand Transfer Inhibitors (INSTIs)

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Dalimune 50mg Tablet

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dalimune Tablet

Benefits of Dalimune Tablet

Side effects of Dalimune Tablet

How to use Dalimune Tablet

How Dalimune Tablet works

All substitutes for Dalimune 50mg Tablet

Instgra Tablet

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Apalutamide (Oral Route)

Bosentan (Oral Route)

Calcium (Oral Route)

Carbamazepine (Oral Route)

Dabrafenib (Oral Route)

Frequently asked questions

What is Dalimune 50mg Tablet used for?

Who should not take Dalimune 50mg Tablet?

Are there any serious warnings with Dalimune 50mg Tablet?

Can Dalimune 50mg Tablet affect my mood or mental health?

What should I know about liver health while taking Dalimune 50mg Tablet?

Does Dalimune 50mg Tablet cause weight changes or affect metabolism?

Can Dalimune 50mg Tablet be used in children and older adults?

How long does it take for Dalimune 50mg Tablet to work?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

HIV 1 & 2, Ab Western Blot

HIV 1 And 2 Antibody - Chromatography

HIV 1 And 2 Antibody - ELISA

References

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

Related/Popular tests