Cytoblastin 10mg Injection is an anti-cancer medication used in the treatment of breast cancer, kidney cancer, Hodgkin’s disease, and Non-Hodgkin's lymphoma.

Cytoblastin 10mg Injection is given as an injection into the vein under the supervision of a doctor. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to.

The most common side effects of this medicine include nausea, vomiting, diarrhea, and decreased appetite. This medicine may reduce the number of blood cells (white blood cells) in your blood, thereby, increasing the susceptibility to infections and fever. In some cases, it may also cause kidney disease related to uric acid level. Regular blood tests are required to check your blood cells along with heart, liver, and blood uric acid levels.

Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. The use of effective contraception by both males and females during treatment is important to avoid pregnancy. You should take precautions while taking this medication as it may cause inflammation of mouth and lips and neurological toxicity.

Uses of Cytoblastin Injection

Side effects of Cytoblastin Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Cytoblastin

Decreased white blood cell count (lymphocytes)
High blood pressure
General discomfort
Bone pain
Tumor pain
Jaw pain
Hair loss
Constipation

How to use Cytoblastin Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Cytoblastin Injection works

Cytoblastin 10mg Injection blocks replication of genetic material (DNA) in the cancer cells. Thus it stops the growth and multiplication of cancer cells.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Cytoblastin 10mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

Cytoblastin 10mg Injection is unsafe to use during pregnancy as there is definite evidence of risk to the developing baby. However, the doctor may rarely prescribe it in some life-threatening situations if the benefits are more than the potential risks. Please consult your doctor.

Breast feeding

UNSAFE

Cytoblastin 10mg Injection is unsafe to use during breastfeeding. Data suggests that the drug may cause toxicity to the baby.

Driving

UNSAFE

Cytoblastin 10mg Injection may cause side effects which could affect your ability to drive.

Kidney

SAFE IF PRESCRIBED

Cytoblastin 10mg Injection is safe to use in patients with kidney disease. No dose adjustment of Cytoblastin 10mg Injection is recommended.
However, talk to your doctor if you have any underlying kidney disease.

Liver

CAUTION

Cytoblastin 10mg Injection should be used with caution in patients with liver disease. Dose adjustment of Cytoblastin 10mg Injection may be needed. Please consult your doctor.
Use of Cytoblastin 10mg Injection may not be advised in patients with severe liver disease.

What if you forget to take Cytoblastin Injection?

If you miss a dose of Cytoblastin 10mg Injection, please consult your doctor.

All substitutes

For informational purposes only. Consult a doctor before taking any medicines.

Cytoblastin 10mg Injection

₹236/Injection

Uniblastin 10mg Injection

United Biotech Pvt Ltd

₹267/injection

same price

Quick tips

Cytoblastin 10mg Injection is given as an IV infusion or injection into a vein under the supervision of a doctor.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
Your doctor may get regular blood tests done to monitor your blood cell count, platelet count, uric acid level and liver function.
Inform your doctor if you experience a skin rash, swelling of face or lips and trouble breathing.

Fact Box

Chemical Class

Vinca alkaloids

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Microtubule Dynamics Inhibitors- Vinka Alkaloids

Interaction with drugs

Taking Cytoblastin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Amiodarone (Injection Route) Severe

Concomitant use is not recommended. Please consult with your doctor. Amiodarone may raise blood levels of Vinblastine. Concurrent use may cause hairloss, drop in blood cell counts,... More

Azithromycin (Oral Route) Severe

Concomitant use is not recommended. Please consult with your doctor. Azithromycin may raise blood levels of Vinblastine. Concurrent use may cause hairloss, drop in blood cell count... More

Filgrastim (Injection Route) Severe

Do not consume Filgrastim from 24 hours before or 24 hours after taking Vinblastine. Vinblastine may reduce the efficacy of Filgrastim.

Amiodarone (Oral Route) Severe

Concomitant use is not recommended. Please consult with your doctor. Amiodarone may raise blood levels of Vinblastine. Concurrent use may cause hairloss, drop in blood cell counts,... More

Azithromycin (Injection Route) Severe

Concomitant use is not recommended. Please consult with your doctor. Azithromycin may raise blood levels of Vinblastine. Concurrent use may cause hairloss, drop in blood cell count... More

View all drug interactions

Patient concerns

Non Hodgkin lymphoma of defuss large b cells

Dr. Vijay Sharnangat

Medical Oncology and Hematology

I am very much experienced in treating DLBCL

I have non hodgking's lymphoma. What type of treament i need? And it this cancer curable?

Dr. Sanjay Singh Rai

Medical Oncology and Hematology

If CD 20+ TAKE R-CHOP TREATMENT

User feedback

What are you using Cytoblastin Injection for?

Others

71%

Hodgkin’s dis*

29%

*Hodgkin’s disease

How much was the improvement?

Excellent

100%

What were the side-effects while using Cytoblastin 10mg Injection?

Decreased whi*

100%

*Decreased white blood cell count

How do you take Cytoblastin Injection?

With food

100%

FAQs

Is Cytoblastin 10mg Injection a vesicant?

Cytoblastin 10mg Injection is a vesicant (irritant) and can cause damage to the blood vessels if it is not administered properly.

How is Cytoblastin 10mg Injection administered?

Cytoblastin 10mg Injection is administered by intravenous route only.

Does Cytoblastin 10mg Injection cause hair loss/infertility?

Yes, Cytoblastin 10mg Injection may cause hair loss/infertility.

How does Cytoblastin 10mg Injection prevent mitosis?

Cytoblastin 10mg Injection prevents mitosis by inhibition of microtubule formation.

Related lab tests

Breast Cancer (CA 15.3/ ER/ PR)

Complete Blood Count

Related ayurvedic ingredients

Olive oil

Soybean

Want to share the information?

Disclaimer:

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1706.
Chu E, Sartorelli AC. Cancer Chemotherapy. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 949.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1476-77.
Drugs and Lactation Database (LactMed) [Internet]. Bethesda (MD): National Library of Medicine (US); 2006. Vinblastine. [Updated 2018 Dec 3]. [Accessed 19 Feb. 2020] (online) Available from: