Critposa 18mg Injection

Posaconazole (18mg)

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Critposa 18mg Injection is an antifungal medicine used to prevent and treat severe fungal infections, particularly in people with weakened immune systems. It is commonly prescribed to prevent invasive infections caused by Aspergillus and Candida species and to treat fungal infections of the mouth and throat.

Written By Dr. Syeda Aafia, MBA, BDS,
Reviewed By Dr. Rajeev Sharma, MBA, MBBS,
Last updated on 25 May 2026 | 05:59 PM (IST)

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General Information

Contains

Posaconazole (18mg)

Marketer

Cipla Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Do not self-administer this medicine. Your doctor or nurse will teach you the correct way of injecting it. To get the most benefit, take this medicine at evenly spaced times and continue using it until your prescription is finished, even if your symptoms disappear after a few days. If you stop treatment too early, the infection may return and if you miss doses you can increase your risk of infections that are resistant to further treatment.

The most common side effects of this medicine include diarrhea, nausea, fever, vomiting, headache, coughing, and hypokalemia. These are not usually serious, but you should call your doctor if you think you might have a severe allergic reaction and signs of liver problems such as yellowing of eyes, dark urine, and stomach problems. Get emergency help if this happens.

Do not take it if you are pregnant or could become pregnant unless your doctor has told you to. Talk to your doctor before taking it if you have ever had heart failure, kidney problems, or liver problems such as yellow skin (jaundice). This medicine may not be suitable for you. If your course of treatment is for more than a month, your doctor may want to check your liver, and potassium level by testing your blood. This medicine may make you dizzy or have blurred vision so do not drive or operate machines until it is safe.

Uses of Critposa Injection

Treatment of Severe fungal infections

Benefits of Critposa Injection

Treatment of Severe fungal infections
Critposa 18mg Injection is an antifungal medicine used to treat serious fungal infections. It is especially beneficial for patients who are severely immunocompromised, such as those with cancer or those undergoing chemotherapy or blood transfusions. This medicine is administered by a doctor or a nurse and should not be self-administered. The dose and duration of treatment will be determined by your doctor based on your condition. It is important to complete the full course of treatment, even if you start feeling better, to ensure the infection is fully cleared and does not return.

Side effects of Critposa Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Critposa

Fever
Decreased potassium level in blood
Diarrhea
Vomiting
Headache
Nausea
Cough
Increased calcium level in blood

How to use Critposa Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Critposa Injection works

Critposa 18mg Injection is an antifungal that works by inhibiting the enzyme essential for the synthesis of ergosterol, a key component of fungal cell membranes. It disrupts the production of ergosterol, damaging the fungal cell membrane, leading to cell death. This action makes it effective in preventing and treating invasive Aspergillus and Candida infections in immunocompromised patients, as well as treating oropharyngeal candidiasis, including cases resistant to other azoles like itraconazole or fluconazole.

Quick tips

Do not skip any doses and finish the full course of treatment even if you feel better.
It is given as an injection under the supervision of a healthcare professional.
Your doctor may check your liver function before starting treatment and regularly thereafter. Inform your doctor if you notice yellowing of eyes or skin, dark urine, or stomach pain.
Inform your doctor if you are pregnant, planning pregnancy or breastfeeding.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Critposa 18mg Injection. Please consult your doctor.

Pregnancy

CONSULT YOUR DOCTOR

The safety of Critposa 18mg Injection during pregnancy has not been established. There are no adequate and well-controlled studies in pregnant women, and animal data on reproductive toxicity are insufficient. Your doctor will weigh the benefits and any potential risks before prescribing.

Breast feeding

CONSULT YOUR DOCTOR

Critposa 18mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

CONSULT YOUR DOCTOR

It is not known whether Critposa 18mg Injection alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Please consult your doctor.
As you may feel dizzy, sleepy, or have blurred vision while taking Critposa 18mg Injection, which may affect your ability to drive.

Kidney

CAUTION

Critposa 18mg Injection should be used with caution in patients with kidney disease. Dose adjustment may be needed.
Regular monitoring of kidney function tests is advised while taking this medicine. Use of Critposa 18mg Injection is not recommended in patients with moderate to severe kidney disease.

Liver

CAUTION

Critposa 18mg Injection should be used with caution in patients with severe liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Critposa with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Life-threatening

Simvastatin (Oral Route)

Do not consume Simvastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Simvastatin. Posaconazole may raise blood levels of Simvastatin.

Life-threatening

Lovastatin (Oral Route)

Do not consume Lovastatin with Posaconazole. If Posaconazole is essential, your doctor may temporarily stop Lovastatin. Posaconazole may raise blood levels of Lovastatin.

Severe

Atorvastatin (Oral Route)

Do not consume Atorvastatin with Posaconazole. If concurrent use is essential, watch out for symptoms such as muscle pains or weakness and consult your doctor if you experience them. They may adjust the doses as per the observations.

Severe

Ranolazine (Oral Route)

Do not consume Ranolazine with Posaconazole. If concurrent use is essential, watch out for symptoms of Ranolazine side effects such as nausea, vomiting, headache, dizziness, constipation or weakness and consult your doctor if you experience them. They may adjust the dose of Ranolazine accordingly. Posaconazole may raise blood levels of Ranolazine.

Severe

Pimozide (Oral Route)

Do not consume Pimozide with Posaconazole.

Frequently asked questions

How is Critposa 18mg Injection administered?

Critposa 18mg Injection is administered under the supervision of a trained healthcare professional or a doctor and should not be self administered. The dose will depend on the condition you are being treated for and will be decided by your doctor. Follow your doctor’s instructions carefully to get maximum benefit from Critposa 18mg Injection.

What is Critposa 18mg Injection, and what is it used for?

Critposa 18mg Injection belongs to a class of medicines known as antifungal agents. It is used to treat serious fungal infections caused by organisms such as Aspergillus and Candida, particularly in patients who are at high risk of developing these infections. Critposa 18mg Injection is mainly prescribed to severely immunocompromised individuals, such as those with cancer or those undergoing chemotherapy or blood transfusions.

How is Critposa 18mg Injection administered?

Critposa 18mg Injection is administered under the supervision of a doctor or nurse and should not be self-administered. The dose depends on the condition being treated and will be determined by your doctor. It is important to follow your doctor’s instructions carefully to gain the maximum benefit from Critposa 18mg Injection.

Is Critposa 18mg Injection effective?

Critposa 18mg Injection is effective when used in the dose and duration prescribed by your doctor. Do not stop taking it even if your symptoms improve. Stopping the medication too early may cause the infection to return or worsen.

What are the side effects of Critposa 18mg Injection?

Some common side effects of Critposa 18mg Injection include cough, headache, nausea, and vomiting. These side effects are generally mild and tend to resolve on their own. However, consult your doctor if any of these symptoms persist or cause concern.

Fact Box

Chemical Class

Phenylpiperazines

Habit Forming

Action Class

Fungal Ergosterol Synthesis Inhibitor

References

Bennett JE. Antifungal Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. New York, New York: McGraw-Hill Medical; 2011. pp. 1581-82.
Sheppard D, Lampiris HW. Antifungal Agents. In: Katzung BG, Masters SB, Trevor AJ, editors. Basic and Clinical Pharmacology. 11th ed. New Delhi, India: Tata McGraw Hill Education Private Limited; 2009. p. 841.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 1135-36.
Posaconazole. White House Station, New Jersey: Merck & Co.; 2015. [Accessed 29 Mar. 2019] (online) Available from:
Posaconazole. Hoddesdon, Hertfordshire: Merck Sharp & Dohme Limited; 2005 [revised 6 Jul. 2018]. [Accessed 29 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Cipla Ltd
Address: Cipla House, Peninsula Business Park, Ganpatrao Kadam Marg, Lower Parel, Mumbai-400013

Vendor Details

Country of origin: India

Lab tests offered by us

Why we need a prescription?

Critposa 18mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Critposa Injection

Benefits of Critposa Injection

Side effects of Critposa Injection

How to use Critposa Injection

How Critposa Injection works

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Simvastatin (Oral Route)

Lovastatin (Oral Route)

Atorvastatin (Oral Route)

Ranolazine (Oral Route)

Pimozide (Oral Route)

Frequently asked questions

How is Critposa 18mg Injection administered?

What is Critposa 18mg Injection, and what is it used for?

How is Critposa 18mg Injection administered?

Is Critposa 18mg Injection effective?

What are the side effects of Critposa 18mg Injection?

Fact Box

Chemical Class

Habit Forming

Action Class

References

User feedback

What are you using Critposa Injection for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

Lab tests offered by us

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