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MD (Pharmacology), MBBS
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MD (Pharmacology), MBBS
Last updated on:
02 Apr 2019 | 10:00 AM (IST)
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Cotaspirin 500 mg Tablet

Prescription Required


Uses of Cotaspirin Tablet

Cotaspirin Tablet side effects

  • Gastrointestinal irritation
  • Nausea
  • Vomiting
  • Dyspepsia
  • Gastritis
  • Bleeding disorder
  • Low blood platelets
  • Gastric erosion
  • Gastric ulcer

How to use Cotaspirin Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Cotaspirin 500 mg Tablet is to be taken with food.

How Cotaspirin Tablet works

Aspirin is a non-steroidal anti-inflammatory drug (NSAID). It works by blocking the release of certain chemical messengers that cause fever, pain, and inflammation (redness and swelling).

Cotaspirin Tablet related warnings

It is unsafe to consume alcohol with Cotaspirin 500 mg Tablet. Taking Cotaspirin 500 mg Tablet with alcohol increases the associated risk of stomach bleeding.
Cotaspirin 500 mg Tablet is unsafe to use during pregnancy.
There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
Cotaspirin 500 mg Tablet is probably unsafe to use during lactation. Limited human data suggest that the drug could represent a significant risk to the baby.
Cotaspirin 500 mg Tablet may make you feel dizzy, drowsy or affect your vision. Do not drive until your vision is clear.
Cotaspirin 500 mg Tablet should be used with caution in patients with kidney disease. Dose adjustment of Cotaspirin 500 mg Tablet may be needed. Please consult your doctor.
Use of Cotaspirin 500 mg Tablet is not recommended in patients with severe kidney disease.
Cotaspirin 500 mg Tablet should be used with caution in patients with liver disease. Dose adjustment of Cotaspirin 500 mg Tablet may be needed. Please consult your doctor.
Use of Cotaspirin 500 mg Tablet is not recommended in patients with severe liver disease.

Alternate Brands

For informational purposes only. Consult a doctor before taking any medicines.
No alternate brands found for this medicine

Expert Advice

  • Cotaspirin 500 mg Tablet is an everyday painkiller for aches and pains such as headache, toothache and period pain. 
  • It may also be used to treat colds and flu-like symptoms, and to bring down a fever.
  • Stop taking Cotaspirin 500 mg Tablet and tell your doctor if you have ringing in your ears, unusual bleeding, or nausea or vomiting that does not go away.

Interaction with Drugs

Taking Cotaspirin with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Brand(s): Nimsun, Abinim, Nimulis
Brand(s): Defmark, Zacdef, Ecodef
Brand(s): Ranisol, Vepred, Catapred
Brand(s): Zencort-M, Welone
Brand(s): Methosis
Brand(s): Budojet
Brand(s): Losin, Tosar

Patient Concerns

Questions Related to Cotaspirin

What are the 3 Loading tablets to prevent heart attackDisprin atorvastatin and another tablet starts with the letter c
Dr. Nabajit Talukdar
Heart Specialist
Clopidogrel but is better to take under medical supervision
I was on glimison m 1/500 . Half tablet per day Diabetes was in control but i heard somewhere that metfprmin is npt good for kidney my creatinine level stays between 1.0 to 1.7 can i use only glimipiride? Is it safe my suger level is around 100_110 in morning. And what would be the require dose? 1_2_3 mg?? I had heart attack and 3 arteries are block pumping is 20%
Dr. Jagruti Shah
Diabetes Specialist
You can get you E-GFR. when you do s.creatinine eIf it is more than 60 then you can safely continue the same drugs if post lunch sugars are acceptable that is less than 140 mg %. Some times it is safer better to change more kidney friendly drugs and small dose of insulin.
Do you have any questions related to Cotaspirin 500 mg Tablet?


Q. Is there any interaction between Cotaspirin and vitamin D?

No, drug-drug interactions or additional harmful effects have been reported when Cotaspirin and vitamin D are used together.

Q. Does Cotaspirin really work for acne?

Cotaspirin contains acetyl salicylic acid. And salicylic acid is a common component of most of the topical (local application) creams of acne. However, Cotaspirin as such is not used in the management of acne.

Q. Can I take Cotaspirin with Tamsulosin?

Cotaspirin and Tamsulosin can be taken together. There are no known drug-drug interactions when they are used together.

Q. How does Cotaspirin act as an antiplatelet drug?

Cotaspirin blocks the enzyme cyclooxygenase which is necessary for the production of thromboxane. Thromboxane normally acts as a pro-aggregatory agent causing the platelets to clump and form a clot. Hence, Cotaspirin by blocking the action of thromboxane functions as an antiplatelet drug.

Q. Can I take fexofenadine with Cotaspirin?

Yes, you can take fexofenadine with Cotaspirin. Fexofenadine is an anti-histaminic drug used for the treatment of allergic diseases and Cotaspirin is a NSAID (non-steroidal inflammatory drug) and has antiplatelet action and helps to relieve pain, fever, and swelling. There are no reported drug interactions or harmful effects when they are used together.

Q. Can I take ibuprofen after Cotaspirin?

It is advisable to not take ibuprofen with Cotaspirin. Your doctor can suggest an alternative. Ibuprofen can decrease the antiplatelet effect of Cotaspirin. When taken together, they can cause increased anticoagulation and potassium levels. Also, Cotaspirin can increase the level of ibuprofen. If needed, take ibuprofen 8 hours before Cotaspirin or 2 to 4 hours after.

Q. Does Cotaspirin cause H. pylori infection?

Cotaspirin is not known to cause Helicobacter Pylori infection. However, its use in patients already having H. pylori infection can cause an increased risk of stomach ulcers and bleeding due to these ulcers.

Q. How is Cotaspirin helpful to prevent stroke?

Cotaspirin helps in stopping the processes of platelet adhesion and aggregation (clumping of platelets). Thereby, the risk of formation of blood clots in the vessels supplying the brain is reduced leading to lesser chances of occurrences of stroke.

Q. Are Cotaspirin and ASA (acetylsalicylic acid) the same?

Yes, Cotaspirin and ASA (acetylsalicylic acid) are the names for the same medicine. Aspirin is called acetylsalicylic acid, as it is an acetyl derivative of the salicylic acid and is commonly abbreviated as ASA.

Q. Is Cotaspirin an NSAID (non-steroidal anti-inflammatory drug)?

Yes, Cotaspirin is a NSAID (non-steroidal anti-inflammatory drug). In low doses, it protects the heart and prevents heart attacks and stroke. In higher doses, it relieves mild to moderate pain, fever, and inflammation and is useful in arthritis, minor body aches, and pains and headache.

Q. Why is Cotaspirin contraindicated in patients with asthma?

Yes, use of Cotaspirin is contraindicated in patients with asthma, rhinitis and nasal polyps. Cotaspirin can cause allergic reactions like urticaria (raised, itchy, skin rashes), angioedema (swelling of skin and tissue under the skin), or bronchospasm (narrowing of the airway).

Q. Is Cotaspirin bad for your liver?

No, as such Cotaspirin does not harm your liver. However, if you already have some liver disorder or haven taken Cotaspirin at high doses, there can be occurrence Cotaspirin-related toxicity. Hence, it is necessary to disclose your liver condition to the treating physician.

Q. How and where is Cotaspirin metabolized?

After oral intake, Cotaspirin rapidly gets converted to salicylic acid, its major active circulating form. Both are primarily metabolized (broken down) in the liver to salicyluric acid and products like phenolic and acyl glucuronides and others. All metabolites are excreted through the kidneys.

Q. What are the allergic reactions to Cotaspirin?

Allergic reactions to Cotaspirin can predominantly affect the respiratory airway tract causing nasal congestion, running nose and difficulty in breathing or the allergic reactions can be limited resulting in urticaria (raised, itchy, skin rashes) and angioedema (swelling of the lower layer of skin and tissue just under the skin).

Q. Can I take Cotaspirin and clopidogrel together?

Yes, you can take Cotaspirin and clopidogrel together. Fixed-dose combinations of clopidogrel and Cotaspirin are available and effectively lowers the risk of heart attack and is used in patients after a coronary artery stent but it can increase the risk of bleeding.

Q. Is Cotaspirin a blood thinner?

Yes, Cotaspirin acts as a blood thinner. In low doses, it has antiplatelet action and it prevents the platelets from sticking together. This helps to decrease the risk of blood clot formation in blood vessels and provides protection from heart attack and stroke.

Q. Is Cotaspirin beneficial in certain diseases of heart?

Yes, at low dose, Cotaspirin is beneficial for patients who are at an increased risk of heart attack and stroke. It is also advised after stent placement or coronary artery bypass. In low doses, it does not allow the platelets to stick together and decreases the risk of blood clot formation.

Q. Is Cotaspirin good for hair growth?

No, Cotaspirin is not known to play any role in hair growth. It is a NSAID (non-steroidal anti-inflammatory drug). In low doses, it protects the heart and prevents heart attacks and stroke. In higher doses, it relieves mild to moderate pain, fever, and inflammation

Q. Is Cotaspirin safe?

Cotaspirin is safe to use in the doses as advised by the doctor, however, there are some common side effects associated with its use like nausea, vomiting, dyspepsia, gastritis, bleeding disorder, decreased blood platelets, gastric erosion, and gastric ulcer.

Q. Is Cotaspirin good for a hangover headache?

No, Cotaspirin should not be used for alcohol hangover/ hangover headache. Alcohol use cause damage to the stomach lining and use of aspirin along with can increase the risk of stomach bleeding.

Q. Can I take Cotaspirin empty stomach?

Yes, Cotaspirin can be taken in an empty stomach particularly to increase its rate and extent of absorption, as the presence of food interferes with Cotaspirin absorption. Having said so, aspirin taken in an empty stomach can irritate the stomach surface and cause erosions.

Q. Can I take Cotaspirin with famotidine?

Cotaspirin can be taken with famotidine. Cotaspirin is a pain killer and belongs to the group of NSAIDs (non-steroidal anti-inflammatory agents) which can increase the gastric acid secretion and worsen stomach acidity, heartburn, and stomach ulcers and drugs like Famotidine are used to prevent and treat gastric problems caused by painkillers.

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