Product introduction
Cosmegen 0.5mg Injection is used for the treatment of several kinds of cancer such as some kinds of cancer that affect the testicles (testicular cancer), uterus or womb (gestational trophoblastic neoplasia), kidneys (Wilms' tumor), bones and muscles (Ewing's sarcoma).
Cosmegen 0.5mg Injection works by interfering with the growth of cancer cells, which are eventually destroyed. It is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.
The most common side effects of this medicine include nausea, vomiting, mouth ulcers and loss of appetite. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.
Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine.
Uses of Cosmegen Injection
Benefits of Cosmegen Injection
In Testicular cancer
Testicular cancer is the cancer in the male organs called testicles, that make male hormones and sperm. The testicles are located inside a loose bag of skin (scrotum) underneath the penis. Cosmegen 0.5mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.
In Gestational trophoblastic neoplasia
Gestational trophoblastic disease (GTD), is a rare tumor that develops inside the uterus from the tissue that forms after the female conceives (successful fusion of sperm and egg). Cosmegen 0.5mg Injection is given to kill such kinds of tumor cells and prevent their further growth. This medicine is given only under medical guidance. Consult your doctor if you have any doubts.
Side effects of Cosmegen Injection
Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them
Common side effects of Cosmegen
- Inflammation of the rectum
- Low blood platelets
- Nausea
- Vomiting
- Loss of appetite
- Glossitis (tongue inflammation)
- Lip inflammation
- Diarrhea
How to use Cosmegen Injection
Your doctor or nurse will give you this medicine. Kindly do not self administer.
How Cosmegen Injection works
Cosmegen 0.5mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.
Safety advice
Alcohol
CONSULT YOUR DOCTOR
It is not known whether it is safe to consume alcohol with Cosmegen 0.5mg Injection. Please consult your doctor.
Pregnancy
UNSAFE
Cosmegen 0.5mg Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.
Breast feeding
CONSULT YOUR DOCTOR
Cosmegen 0.5mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.
Driving
UNSAFE
Cosmegen 0.5mg Injection may cause side effects that could affect your ability to drive.
Kidney
CONSULT YOUR DOCTOR
There is limited data available on the use of Cosmegen 0.5mg Injection in patients with kidney disease. Please consult your doctor.
Liver
CAUTION
Cosmegen 0.5mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.
What if you forget to take Cosmegen Injection?
If you miss a dose of Cosmegen 0.5mg Injection, please consult your doctor.
All substitutes
For informational purposes only. Consult a doctor before taking any medicines.
Cosmegen 0.5mg Injection
₹89.8/Injection
Dacilon 0.5mg Injection
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₹353.5/injection
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Tinowel 0.5mg Injection
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₹345/injection
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Quick tips
- Cosmegen 0.5mg Injection is given as an injection into vein under the supervision of a doctor only.
- Do not skip any dose and complete the course as suggested by your doctor.
- Use an effective method of birth control to avoid pregnancy while taking this medication.
- You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
- Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and dark urine.
Fact Box
Chemical Class
Cyclic depsipeptides
Habit Forming
No
Therapeutic Class
ANTI NEOPLASTICS
Action Class
Cytotoxic Alkaloids
Interaction with drugs
Taking Cosmegen with any of the following medicines can modify the effect of either of them and cause some undesirable side effects
Do not use Dactinomycin with Purified Vi Polysaccharide Typhoid Vaccine. If Purified Vi Polysaccharide Typhoid Vaccine is essential, ensure a gap of At least 6 months after discont
Do not consume Filgrastim from 24 hours before or 24 hours after taking Dactinomycin. Dactinomycin may reduce the efficacy of Filgrastim.
Do not use Dactinomycin with Cholera Vaccine (Inactivated). If Cholera Vaccine (Inactivated) is essential, ensure a gap of At least 6 months after discontinuing Dactinomycin. Pleas
Do not use Dactinomycin with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) is essential, ensure a gap of
Do not consume Pegfilgrastim from 24 hours before or 24 hours after taking Dactinomycin. Dactinomycin may reduce the efficacy of Pegfilgrastim.
Patient concerns
FAQs
What is Cosmegen 0.5mg Injection used for?
Cosmegen 0.5mg Injection is a cancer medicine used to treat several types of tumors, including Wilms tumor (kidney cancer in children), rhabdomyosarcoma (muscle cancer), Ewing sarcoma (cancer of bones and soft tissues around it), certain testicular cancers, gestational trophoblastic disease, and some locally recurrent solid tumors. Doctors use it as part of a planned chemotherapy program.<br>
What serious risks should I know about before starting Cosmegen 0.5mg Injection?
The important risks associated with Cosmegen 0.5mg Injection use include severe liver problems (including a condition called veno-occlusive disease), very low blood counts (which can increase infection or bleeding risk), severe skin or mouth reactions, secondary cancers that may develop years later, and worsened side effects if combined with radiation therapy. Your doctor monitors you closely to catch these early.<br>
Can Cosmegen 0.5mg Injection cause secondary cancer later in life?
Yes. Cosmegen 0.5mg Injection can increase the long-term risk of developing another cancer, such as leukemia, many years after treatment. This is rare, but important to understand.<br>
What symptoms should I urgently report while on Cosmegen 0.5mg Injection?
While on Cosmegen 0.5mg Injection treatment, call your doctor immediately if you notice unusual bleeding or bruising, fever or signs of infection, severe fatigue, yellowing of the skin or eyes, pain or swelling at the injection site, and severe mouth sores or rashes. These can be signs of serious side effects.<br>
Does Cosmegen 0.5mg Injection affect my liver or kidneys?
Yes. Cosmegen 0.5mg Injection can cause liver damage, and may also affect kidney function. Regular blood tests are done before and during treatment to check for changes.<br>
What happens if Cosmegen 0.5mg Injection leaks outside the vein during injection?
If Cosmegen 0.5mg Injection leaks into the surrounding skin (called extravasation), it can cause tissue damage. Doctors and nurses are trained to stop the infusion immediately and apply ice to reduce injury.<br>
Can I receive vaccines while I am taking Cosmegen 0.5mg Injection?
You should avoid live vaccines during Cosmegen 0.5mg Injection treatment because your immune system may be weakened. Always check with your doctor before getting any vaccine.<br>
I am getting radiation therapy. Does Cosmegen 0.5mg Injection affect it?
Yes. Cosmegen 0.5mg Injection can intensify radiation side effects and may also cause a reaction in previously treated radiation areas (radiation recall). Your doctor may adjust the dose if you are receiving both treatments.<br>
Who should not take Cosmegen 0.5mg Injection?
There are no specific contraindications listed, but Cosmegen 0.5mg Injection must be used with extreme caution in people with severe infections, very weak immune systems, or liver problems. Your doctor will evaluate your overall condition before treatment.<br>
Can Cosmegen 0.5mg Injection harm an unborn baby?
Yes. Cosmegen 0.5mg Injection can cause severe harm to an unborn baby. People who can become pregnant must use effective birth control during treatment, and for a period after. You should not breastfeed while receiving this medicine.<br>
Will I need frequent blood tests during Cosmegen 0.5mg Injection treatment?
Yes. During Cosmegen 0.5mg Injection treatment, regular blood tests are essential to monitor your blood counts, liver function, kidney function, and overall response. This helps ensure the medicine remains safe for you throughout treatment.<br>
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Disclaimer:
Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.References
- Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1712-13.
- Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 348-49.
- Dactinomycin. Immeuble Le Wilson: Orphan Europe SARL; 2006 [revised Jun. 2013]. [Accessed 26 Mar. 2019] (online) Available from:
Marketer details
Name: Wockhardt Ltd
Address: Wockhardt Towers, Bandra Kurla Complex, Bandra (East), Mumbai 400051, Maharashtra, India
Country of origin: India
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₹89.8
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