Dacilon 0.5mg Injection

Reviewed By Dr. Mekhala Chandra, MD, MBBS

Last updated on 14 Apr 2026 | 04:20 PM (IST)

Dacilon 0.5mg Injection is used for the treatment of several kinds of cancer such as some kinds of cancer that affect the testicles (testicular cancer), uterus or womb (gestational trophoblastic neoplasia), kidneys (Wilms' tumor), bones and muscles (Ewing's sarcoma).

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General Information

Contains

Dactinomycin (0.5mg)

Marketer

Celon Laboratories Ltd

Storage

Store below 30°C

The content is shown in English

Product introduction

Dacilon 0.5mg Injection works by interfering with the growth of cancer cells, which are eventually destroyed. It is given under the supervision of a healthcare professional and should not be self-administered. It might be given as a single therapy or in combination with some other medication. Your doctor will decide what dose is necessary and how often you need to take it. This will depend on what you are being treated for and may change from time to time. You should take it exactly as your doctor has advised. Taking it in the wrong way or taking too much can cause very serious side effects. It may take several weeks or months for you to see or feel the benefits but do not stop taking it unless your doctor tells you to. You should avoid drinking alcohol as it may increase your risk of liver damage.

The most common side effects of this medicine include nausea, vomiting, mouth ulcers and loss of appetite. If they do not go away or get worse, tell your doctor. There may be ways of preventing or reducing these effects. It is very strong medicine and some people may develop serious side effects while taking it. This medicine may lower your ability to fight infections and lead to problems with your blood, liver or kidneys. Your doctor will advise you regular blood tests to check for these.

Before taking it, tell your doctor if you have liver, or kidney problems or are taking any medicines to treat infections. Many other medicines can affect, or be affected by, this medicine so let your doctor know all medications you are using. This medicine is not recommended during pregnancy or while breastfeeding. It may harm your baby. You and your partner should avoid becoming pregnant or fathering a child for several months after your treatment with it has stopped. Your doctor may perform several tests such as blood tests, and physical examinations both before and during treatment with this medicine.

Uses of Dacilon Injection

Benefits of Dacilon Injection

Testicular cancer
Testicular cancer is the cancer in the male organs called testicles, that make male hormones and sperm. The testicles are located inside a loose bag of skin (scrotum) underneath the penis. Dacilon 0.5mg Injection kills or stops the growth of cancer cells and also prevents the multiplication of cancer cells in men. It is given as an injection by a doctor or nurse and should not be self-administered.

Gestational trophoblastic neoplasia
Gestational trophoblastic disease (GTD), is a rare tumor that develops inside the uterus from the tissue that forms after the female conceives (successful fusion of sperm and egg). Dacilon 0.5mg Injection is given to kill such kinds of tumor cells and prevent their further growth. This medicine is given only under medical guidance. Consult your doctor if you have any doubts.

Side effects of Dacilon Injection

Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Common side effects of Dacilon

Inflammation of the rectum
Low blood platelets
Nausea
Vomiting
Loss of appetite
Glossitis (tongue inflammation)
Lip inflammation
Diarrhea

How to use Dacilon Injection

Your doctor or nurse will give you this medicine. Kindly do not self administer.

How Dacilon Injection works

Dacilon 0.5mg Injection is an anti-cancer medication. It works by damaging the genetic material (DNA) of the cancer cells and stops their growth and multiplication.

All substitutes for Dacilon 0.5mg Injection

For information purposes only. Consult a doctor before taking any medicine.

Tinowel 0.5mg Injection

by Getwell Pharma (I) Pvt Ltd

₹345/injection

2% cheaper

Cosmegen 0.5mg Injection

by Wockhardt Ltd

₹90.58/injection

74% cheaper

Quick tips

Dacilon 0.5mg Injection is given as an injection into vein under the supervision of a doctor only.
Do not skip any dose and complete the course as suggested by your doctor.
Use an effective method of birth control to avoid pregnancy while taking this medication.
You may need to have blood tests to monitor your blood cells, platelets count, liver function and kidney function during treatment.
Inform your doctor immediately if you notice unusual bruising or bleeding or if you have dark, tarry, or bloody stools and dark urine.

Safety advice

Alcohol

CONSULT YOUR DOCTOR

It is not known whether it is safe to consume alcohol with Dacilon 0.5mg Injection. Please consult your doctor.

Pregnancy

UNSAFE

Dacilon 0.5mg Injection is highly unsafe during pregnancy. It can cause serious harm to the unborn baby, including birth defects and pregnancy loss. Do not use this medicine if you are pregnant or planning to become pregnant.

Breast feeding

CONSULT YOUR DOCTOR

Dacilon 0.5mg Injection may be unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby. It should be used only if the expected benefit outweighs the potential risk. Please consult your doctor.

Driving

UNSAFE

Dacilon 0.5mg Injection may cause side effects that could affect your ability to drive.

Kidney

CONSULT YOUR DOCTOR

There is limited data available on the use of Dacilon 0.5mg Injection in patients with kidney disease. Please consult your doctor.

Liver

CAUTION

Dacilon 0.5mg Injection should be used with caution in patients with liver disease. Dose adjustment may be needed.

Interaction with drugs

Taking Dacilon with any of the following medicines can modify the effect of either of them and cause some undesirable side effects

Severe

Cholera Vaccine (Inactivated) (Oral Route)

Do not use Dactinomycin with Cholera Vaccine (Inactivated). If Cholera Vaccine (Inactivated) is essential, ensure a gap of At least 6 months after discontinuing Dactinomycin. Please consult your doctor. Dactinomycin may reduce efficacy of Cholera Vaccine (Inactivated).

Severe

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Do not use Dactinomycin with Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted). If Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) is essential, ensure a gap of At least 6 months after discontinuing Dactinomycin. Please consult your doctor. Dactinomycin may reduce efficacy of Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted).

Severe

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Do not use Dactinomycin with Purified Vi Polysaccharide Typhoid Vaccine. If Purified Vi Polysaccharide Typhoid Vaccine is essential, ensure a gap of At least 6 months after discontinuing Dactinomycin. Please consult your doctor. Dactinomycin may reduce efficacy of Purified Vi Polysaccharide Typhoid Vaccine.

Severe

Filgrastim (Injection Route)

Do not consume Filgrastim from 24 hours before or 24 hours after taking Dactinomycin. Dactinomycin may reduce the efficacy of Filgrastim.

Severe

Pegfilgrastim (Injection Route)

Do not consume Pegfilgrastim from 24 hours before or 24 hours after taking Dactinomycin. Dactinomycin may reduce the efficacy of Pegfilgrastim.

Frequently asked questions

What is Dacilon 0.5mg Injection used for?

Dacilon 0.5mg Injection is a cancer medicine used to treat several types of tumors, including Wilms tumor (kidney cancer in children), rhabdomyosarcoma (muscle cancer), Ewing sarcoma (cancer of bones and soft tissues around it), certain testicular cancers, gestational trophoblastic disease, and some locally recurrent solid tumors. Doctors use it as part of a planned chemotherapy program.

What serious risks should I know about before starting Dacilon 0.5mg Injection?

The important risks associated with Dacilon 0.5mg Injection use include severe liver problems (including a condition called veno-occlusive disease), very low blood counts (which can increase infection or bleeding risk), severe skin or mouth reactions, secondary cancers that may develop years later, and worsened side effects if combined with radiation therapy. Your doctor monitors you closely to catch these early.

Can Dacilon 0.5mg Injection cause secondary cancer later in life?

Yes. Dacilon 0.5mg Injection can increase the long-term risk of developing another cancer, such as leukemia, many years after treatment. This is rare, but important to understand.

What symptoms should I urgently report while on Dacilon 0.5mg Injection?

While on Dacilon 0.5mg Injection treatment, call your doctor immediately if you notice unusual bleeding or bruising, fever or signs of infection, severe fatigue, yellowing of the skin or eyes, pain or swelling at the injection site, and severe mouth sores or rashes. These can be signs of serious side effects.

Does Dacilon 0.5mg Injection affect my liver or kidneys?

Yes. Dacilon 0.5mg Injection can cause liver damage, and may also affect kidney function. Regular blood tests are done before and during treatment to check for changes.

What happens if Dacilon 0.5mg Injection leaks outside the vein during injection?

If Dacilon 0.5mg Injection leaks into the surrounding skin (called extravasation), it can cause tissue damage. Doctors and nurses are trained to stop the infusion immediately and apply ice to reduce injury.

Can I receive vaccines while I am taking Dacilon 0.5mg Injection?

You should avoid live vaccines during Dacilon 0.5mg Injection treatment because your immune system may be weakened. Always check with your doctor before getting any vaccine.

I am getting radiation therapy. Does Dacilon 0.5mg Injection affect it?

Yes. Dacilon 0.5mg Injection can intensify radiation side effects and may also cause a reaction in previously treated radiation areas (radiation recall). Your doctor may adjust the dose if you are receiving both treatments.

Who should not take Dacilon 0.5mg Injection?

There are no specific contraindications listed, but Dacilon 0.5mg Injection must be used with extreme caution in people with severe infections, very weak immune systems, or liver problems. Your doctor will evaluate your overall condition before treatment.

Can Dacilon 0.5mg Injection harm an unborn baby?

Yes. Dacilon 0.5mg Injection can cause severe harm to an unborn baby. People who can become pregnant must use effective birth control during treatment, and for a period after. You should not breastfeed while receiving this medicine.

Will I need frequent blood tests during Dacilon 0.5mg Injection treatment?

Yes. During Dacilon 0.5mg Injection treatment, regular blood tests are essential to monitor your blood counts, liver function, kidney function, and overall response. This helps ensure the medicine remains safe for you throughout treatment.

Fact Box

Chemical Class

Cyclic depsipeptides

Habit Forming

Therapeutic Class

ANTI NEOPLASTICS

Action Class

Cytotoxic Alkaloids

Related lab tests

Beta Human Chorionic Gonodotropin, Free

Beta Human Chorionic Gonodotropin,Tumor marker

References

Chabner BA, Bertino J, Cleary J, et al. Cytotoxic Agents. In: Brunton LL, Chabner BA, Knollmann BC, editors. Goodman & Gilman’s: The Pharmacological Basis of Therapeutics. 12th ed. New York, New York: McGraw-Hill Medical; 2011. p. 1712-13.
Briggs GG, Freeman RK, editors. A Reference Guide to Fetal and Neonatal Risk: Drugs in Pregnancy and Lactation. 10th ed. Philadelphia, PA: Wolters Kluwer Health; 2015. pp. 348-49.
Dactinomycin. Immeuble Le Wilson: Orphan Europe SARL; 2006 [revised Jun. 2013]. [Accessed 26 Mar. 2019] (online) Available from:

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Disclaimer

Tata 1mg's sole intention is to ensure that its consumers get information that is expert-reviewed, accurate and trustworthy. However, the information contained herein should NOT be used as a substitute for the advice of a qualified physician. The information provided here is for informational purposes only. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your doctor and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Marketer details

Name: Celon Laboratories Ltd
Address: Plot No 264, Patrika Nagar Madhapur, Hitech City Hyderabad, Telangana India - 500081

Vendor Details

Country of origin: India
A licensed vendor partner from your nearest location will deliver Dacilon 0.5mg Injection. Once the pharmacy accepts your order, the details of the pharmacy will be shared with you. Acceptance of your order is based on the validity of your doctor's ℞ and the availability of this medicine.

In case of any issues, contact us

Email ID: [email protected]
Phone Number: 0124-4166666
Address: 5th Floor Tower - B of the Presidency Building, 46/4 Mehrauli Gurgaon Road, Sector 14, Gurugram, Haryana-122001, India

Lab tests offered by us

Why we need a prescription?

Dacilon 0.5mg Injection

Save more with additional offers

General Information

Contains

Marketer

Storage

Product introduction

Uses of Dacilon Injection

Benefits of Dacilon Injection

Side effects of Dacilon Injection

How to use Dacilon Injection

How Dacilon Injection works

All substitutes for Dacilon 0.5mg Injection

Tinowel 0.5mg Injection

Cosmegen 0.5mg Injection

Quick tips

Safety advice

Alcohol

Pregnancy

Breast feeding

Driving

Kidney

Liver

Interaction with drugs

Cholera Vaccine (Inactivated) (Oral Route)

Herpes Zoster / Shingles Vaccine (Recombinant, Adjuvanted) (Injection Route)

Purified Vi Polysaccharide Typhoid Vaccine (Injection Route)

Filgrastim (Injection Route)

Pegfilgrastim (Injection Route)

Frequently asked questions

What is Dacilon 0.5mg Injection used for?

What serious risks should I know about before starting Dacilon 0.5mg Injection?

Can Dacilon 0.5mg Injection cause secondary cancer later in life?

What symptoms should I urgently report while on Dacilon 0.5mg Injection?

Does Dacilon 0.5mg Injection affect my liver or kidneys?

What happens if Dacilon 0.5mg Injection leaks outside the vein during injection?

Can I receive vaccines while I am taking Dacilon 0.5mg Injection?

I am getting radiation therapy. Does Dacilon 0.5mg Injection affect it?

Who should not take Dacilon 0.5mg Injection?

Can Dacilon 0.5mg Injection harm an unborn baby?

Will I need frequent blood tests during Dacilon 0.5mg Injection treatment?

Fact Box

Chemical Class

Habit Forming

Therapeutic Class

Action Class

Related lab tests

Beta Human Chorionic Gonodotropin, Free

Beta Human Chorionic Gonodotropin,Tumor marker

References

User feedback

What are you using Dacilon Injection for?

Want to know more

Have issue with the content

Disclaimer

Marketer details

Vendor Details

In case of any issues, contact us

Lab tests offered by us

Related/Popular tests